Page last updated: 2024-09-03

1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and cyproheptadine

1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine has been researched along with cyproheptadine in 1 studies

Compound Research Comparison

Studies
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Trials
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Recent Studies (post-2010)
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)
Studies
(cyproheptadine)
Trials
(cyproheptadine)
Recent Studies (post-2010) (cyproheptadine)
530152,297262201

Protein Interaction Comparison

ProteinTaxonomy1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine (IC50)cyproheptadine (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.0024
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)0.564
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.035
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.016
5-hydroxytryptamine receptor 2CRattus norvegicus (Norway rat)0.0031
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0038
Alpha-2A adrenergic receptorHomo sapiens (human)0.283
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.016
D(2) dopamine receptorHomo sapiens (human)0.164
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)0.0031
Alpha-2B adrenergic receptorHomo sapiens (human)0.038
Alpha-2C adrenergic receptorHomo sapiens (human)1.275
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)0.122
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.046
D(1A) dopamine receptorHomo sapiens (human)0.158
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.564
Histamine H2 receptorHomo sapiens (human)0.198
Alpha-1D adrenergic receptorHomo sapiens (human)0.107
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.001
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.0024
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)0.122
5-hydroxytryptamine receptor 2BRattus norvegicus (Norway rat)0.0031
Histamine H1 receptorHomo sapiens (human)0.0037
D(3) dopamine receptorHomo sapiens (human)0.048
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.0094
5-hydroxytryptamine receptor 6Homo sapiens (human)0.281
D(2) dopamine receptorRattus norvegicus (Norway rat)0.14
Histone-lysine N-methyltransferase SETD7Homo sapiens (human)2.2

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1

Other Studies

1 other study(ies) available for 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and cyproheptadine

ArticleYear
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993