1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine has been researched along with amitriptyline in 1 studies
| Studies (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Trials (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Recent Studies (post-2010) (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Studies (amitriptyline) | Trials (amitriptyline) | Recent Studies (post-2010) (amitriptyline) |
|---|---|---|---|---|---|
| 53 | 0 | 15 | 6,935 | 1,381 | 1,060 |
| Protein | Taxonomy | 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine (IC50) | amitriptyline (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 0.006 | |
| Aldo-keto reductase family 1 member B1 | Rattus norvegicus (Norway rat) | 0.023 | |
| Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.081 | |
| Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0053 | |
| Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.3 | |
| Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.3 | |
| Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.3 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.044 | |
| Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.3 | |
| Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.008 | |
| Alpha-2A adrenergic receptor | Homo sapiens (human) | 0.1755 | |
| Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.3 | |
| Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.011 | |
| D(2) dopamine receptor | Homo sapiens (human) | 1.009 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.044 | |
| Alpha-2B adrenergic receptor | Homo sapiens (human) | 0.004 | |
| Alpha-2C adrenergic receptor | Homo sapiens (human) | 0.0295 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 1.02 | |
| Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.026 | |
| D(1A) dopamine receptor | Homo sapiens (human) | 0.355 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.0324 | |
| Histamine H2 receptor | Homo sapiens (human) | 0.73 | |
| Alpha-1D adrenergic receptor | Homo sapiens (human) | 0.105 | |
| 5-hydroxytryptamine receptor 2A | Homo sapiens (human) | 0.015 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.006 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 1.02 | |
| 5-hydroxytryptamine receptor 1D | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 1F | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 6 | Rattus norvegicus (Norway rat) | 0.044 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.2756 | |
| 5-hydroxytryptamine receptor 7 | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 5A | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 5B | Rattus norvegicus (Norway rat) | 0.044 | |
| Histamine H1 receptor | Homo sapiens (human) | 0.0048 | |
| D(3) dopamine receptor | Homo sapiens (human) | 0.182 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.044 | |
| 5-hydroxytryptamine receptor 2B | Homo sapiens (human) | 0.07 | |
| Histamine H2 receptor | Cavia porcellus (domestic guinea pig) | 0.66 | |
| 5-hydroxytryptamine receptor 6 | Homo sapiens (human) | 0.14 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 7.2446 | |
| Sodium channel protein type 5 subunit alpha | Homo sapiens (human) | 1.6 | |
| Sodium channel protein type 9 subunit alpha | Homo sapiens (human) | 4 | |
| 5-hydroxytryptamine receptor 4 | Rattus norvegicus (Norway rat) | 0.044 | |
| Sodium channel protein type 2 subunit alpha | Homo sapiens (human) | 3.1 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.031 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.044 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP | 1 |
1 other study(ies) available for 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and amitriptyline
| Article | Year |
|---|---|
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 1993 |