1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine has been researched along with 8-hydroxy-2-(di-n-propylamino)tetralin in 11 studies
| Studies (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Trials (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Recent Studies (post-2010) (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Studies (8-hydroxy-2-(di-n-propylamino)tetralin) | Trials (8-hydroxy-2-(di-n-propylamino)tetralin) | Recent Studies (post-2010) (8-hydroxy-2-(di-n-propylamino)tetralin) |
|---|---|---|---|---|---|
| 53 | 0 | 15 | 3,530 | 7 | 389 |
| Protein | Taxonomy | 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine (IC50) | 8-hydroxy-2-(di-n-propylamino)tetralin (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 1A | Homo sapiens (human) | 0.0012 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0032 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Bos taurus (cattle) | 0.8 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 0.81 | |
| D(2) dopamine receptor | Rattus norvegicus (Norway rat) | 2.8959 | |
| Lysosomal alpha-glucosidase | Bos taurus (cattle) | 0.0021 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (72.73) | 18.7374 |
| 1990's | 3 (27.27) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Audinot, V; Chaput, C; Conte, C; Gavaudan, S; Millan, MJ; Newman-Tancredi, A; Touzard, M; Verrièle, L | 1 |
| Jackson, HC; Kitchen, I | 1 |
| Azmitia, EC; Segal, M; Whitaker-Azmitia, PM | 1 |
| Aghajanian, GK; Sprouse, JS | 1 |
| Asarch, KB; Ransom, RW; Shih, JC | 1 |
| Gole, D; Kreiman, MA; Ram, JL | 1 |
| Harris, LT; McCall, RB; Patel, BN | 1 |
| Curzon, G; Donohoe, TP; Hutson, PH | 1 |
| Anderson, EG; Marszalec, W | 1 |
| Bervoets, K; Canton, H; Gobert, A; Millan, MJ; Rivet, JM; Veiga, S | 1 |
| Bobirnac, I; Schoeffter, P | 1 |
11 other study(ies) available for 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and 8-hydroxy-2-(di-n-propylamino)tetralin
| Article | Year |
|---|---|
Agonist and antagonist actions of antipsychotic agents at 5-HT1A receptors: a [35S]GTPgammaS binding study.
Topics: Animals; Antipsychotic Agents; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Receptors, Serotonin; Receptors, Serotonin, 5-HT1; Serotonin Agents; Sulfur Radioisotopes | 1998 |
Behavioural profiles of putative 5-hydroxytryptamine receptor agonists and antagonists in developing rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Behavior, Animal; Grooming; Indoles; Male; Methoxydimethyltryptamines; Motor Activity; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Tetrahydronaphthalenes | 1989 |
Physiological effects of selective 5-HT1a and 5-HT1b ligands in rat hippocampus: comparison to 5-HT.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Hippocampus; In Vitro Techniques; Male; Neural Inhibition; Piperazines; Pyrimidines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Tetrahydronaphthalenes | 1989 |
Responses of hippocampal pyramidal cells to putative serotonin 5-HT1A and 5-HT1B agonists: a comparative study with dorsal raphe neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Anti-Anxiety Agents; Hippocampus; Male; Piperazines; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Receptors, Serotonin; Tetrahydronaphthalenes | 1988 |
[3H]1-[2-(4-aminophenyl)ethyl]-4-(3-trifluoromethylphenyl)piperazine: a selective radioligand for 5-HT1A receptors in rat brain.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Brain; Cerebellum; Cerebral Cortex; Chemical Phenomena; Chemistry; Corpus Striatum; Hippocampus; Kinetics; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Spiperone; Tetrahydronaphthalenes | 1986 |
LY165163 and 8-OH-DPAT have agonist effects on a serotonin responsive muscle of Aplysia.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Acetylcholine; Animals; Aplysia; In Vitro Techniques; Ketanserin; Muscle Contraction; Muscle, Smooth; Naphthalenes; Piperazines; Serotonin; Tetrahydronaphthalenes | 1987 |
Effects of serotonin1 and serotonin2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blood Pressure; Cats; Heart Rate; Piperazines; Pyrazines; Receptors, Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes | 1987 |
Hypothermia induced by the putative 5-HT1A agonists LY165163 and 8-OH-DPAT is not prevented by 5-HT depletion.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Body Temperature; Brain; Desipramine; Fenclonine; Male; Naphthalenes; Nomifensine; Piperazines; Rats; Rats, Inbred Strains; Serotonin; Tetrahydronaphthalenes | 1987 |
Three putative 5-HT1A agonists act as 5-HT antagonists in frog sensory neurons.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Action Potentials; Animals; Buspirone; Ganglia, Spinal; In Vitro Techniques; Naphthalenes; Neurons; Piperazines; Rana catesbeiana; Serotonin Antagonists; Tetrahydronaphthalenes | 1988 |
5-HT1A receptors and the tail-flick response. VI. Intrinsic alpha 1A-adrenoceptor antagonist properties can mask the actions of 5-HT1A receptor agonists in the spontaneous tail-flick paradigm.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-1 Receptor Antagonists; Adrenergic alpha-Antagonists; Animals; Antidepressive Agents; Corticosterone; Drug Interactions; Eyelids; Hypothermia; Male; Models, Biological; Pain Measurement; Piperazines; Pyrimidines; Rats; Rats, Wistar; Receptors, Serotonin; Serotonin Receptor Agonists; Tail | 1994 |
5-Hydroxytryptamine 5-HT1D receptors mediating inhibition of cyclic AMP accumulation in Madin-Darby canine kidney (MDCK) cells.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alprostadil; Animals; Cells, Cultured; Cyclic AMP; Dogs; Dose-Response Relationship, Drug; Drug Interactions; Epithelial Cells; Epithelium; Ketanserin; Kidney Cortex; Methiothepin; Oxadiazoles; Pertussis Toxin; Piperazines; Propranolol; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Structure-Activity Relationship; Sumatriptan; Virulence Factors, Bordetella; Yohimbine | 1995 |