1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine has been researched along with 1-(3-trifluoromethylphenyl)piperazine in 7 studies
| Studies (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Trials (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Recent Studies (post-2010) (1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine) | Studies (1-(3-trifluoromethylphenyl)piperazine) | Trials (1-(3-trifluoromethylphenyl)piperazine) | Recent Studies (post-2010) (1-(3-trifluoromethylphenyl)piperazine) |
|---|---|---|---|---|---|
| 53 | 0 | 15 | 281 | 7 | 23 |
| Protein | Taxonomy | 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine (IC50) | 1-(3-trifluoromethylphenyl)piperazine (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.57 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.57 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.29 | |
| 5-hydroxytryptamine receptor 1D | Homo sapiens (human) | 0.61 | |
| 5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 0.15 | |
| 5-hydroxytryptamine receptor 1B | Rattus norvegicus (Norway rat) | 0.039 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.57 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP | 1 |
| Fuller, RW; Molloy, BB; Snoddy, HD | 1 |
| Harris, LT; McCall, RB; Patel, BN | 1 |
| Schechter, LE; Simansky, KJ | 1 |
| Aghajanian, GK; Sprouse, JS | 1 |
| Cohen, ML; Wittenauer, LA | 1 |
| Asarch, KB; Ransom, RW; Shih, JC | 1 |
7 other study(ies) available for 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and 1-(3-trifluoromethylphenyl)piperazine
| Article | Year |
|---|---|
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection | 1993 |
Central serotonin agonist actions of LY 165163, 1-(m-trifluoromethylphenyl)-4-(p-aminophenylethyl) piperazine, in rats.
Topics: 3,4-Dihydroxyphenylacetic Acid; Amides; Animals; Brain Chemistry; Corticosterone; Dose-Response Relationship, Drug; Homovanillic Acid; Hydroxyindoleacetic Acid; Male; Metergoline; Piperazines; Probenecid; Prolactin; Rats; Rats, Inbred Strains; Structure-Activity Relationship | 1986 |
Effects of serotonin1 and serotonin2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blood Pressure; Cats; Heart Rate; Piperazines; Pyrazines; Receptors, Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes | 1987 |
Properties of some 1-arylpiperazines as antagonists of stereotyped behaviors mediated by central serotonergic receptors in rodents.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Male; Metergoline; Mice; Motor Activity; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Syndrome; Thiazolidines; Thyrotropin-Releasing Hormone | 1988 |
Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists.
Topics: Animals; Lysergic Acid Diethylamide; Male; Neurons; Piperazines; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists | 1987 |
Further evidence that the serotonin receptor in the rat stomach fundus is not 5HT1A or 5HT1B.
Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Gastric Fundus; Male; Mathematics; Muscle Contraction; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists | 1986 |
5-HT-1a and 5-HT-1b selectivity of two phenylpiperazine derivatives: evidence for 5-HT-1b heterogeneity.
Topics: Animals; Binding Sites; Binding, Competitive; Brain; Cerebral Cortex; Corpus Striatum; Male; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Spiperone | 1985 |