Compounds > 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine
Page last updated: 2024-09-03

1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and 1-(3-chlorophenyl)piperazine

1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine has been researched along with 1-(3-chlorophenyl)piperazine in 5 studies

Compound Research Comparison

Studies
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)		Trials
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)		Recent Studies (post-2010)
(1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine)		Studies
(1-(3-chlorophenyl)piperazine)		Trials
(1-(3-chlorophenyl)piperazine)		Recent Studies (post-2010) (1-(3-chlorophenyl)piperazine)
5301583314287

Protein Interaction Comparison

ProteinTaxonomy1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine (IC50)1-(3-chlorophenyl)piperazine (IC50)
Beta-1 adrenergic receptorHomo sapiens (human)2

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hamblin, MW; Monsma, FJ; Shen, Y; Sibley, DR; Ward, RP1
Harris, LT; McCall, RB; Patel, BN1
Schechter, LE; Simansky, KJ1
Aghajanian, GK; Sprouse, JS1
Cohen, ML; Wittenauer, LA1

Other Studies

5 other study(ies) available for 1-(2-(4-aminophenyl)ethyl)-4-(3-trifluoromethylphenyl)piperazine and 1-(3-chlorophenyl)piperazine

ArticleYear
Cloning and expression of a novel serotonin receptor with high affinity for tricyclic psychotropic drugs.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Amino Acid Sequence; Animals; Base Sequence; Binding, Competitive; Blotting, Northern; Brain Chemistry; Cell Line; Cloning, Molecular; DNA; GTP-Binding Proteins; Lysergic Acid Diethylamide; Molecular Sequence Data; Polymerase Chain Reaction; Psychotropic Drugs; Rats; Receptors, Serotonin; RNA; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Transfection

1993
Effects of serotonin1 and serotonin2 receptor agonists and antagonists on blood pressure, heart rate and sympathetic nerve activity.
    The Journal of pharmacology and experimental therapeutics, 1987, Volume: 242, Issue:3

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Blood Pressure; Cats; Heart Rate; Piperazines; Pyrazines; Receptors, Serotonin; Serotonin Antagonists; Sympathetic Nervous System; Tetrahydronaphthalenes

1987
Properties of some 1-arylpiperazines as antagonists of stereotyped behaviors mediated by central serotonergic receptors in rodents.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 247, Issue:3

    Topics: Animals; Brain; Dose-Response Relationship, Drug; Male; Metergoline; Mice; Motor Activity; Piperazines; Rats; Receptors, Serotonin; Serotonin Antagonists; Stereotyped Behavior; Syndrome; Thiazolidines; Thyrotropin-Releasing Hormone

1988
Electrophysiological responses of serotoninergic dorsal raphe neurons to 5-HT1A and 5-HT1B agonists.
    Synapse (New York, N.Y.), 1987, Volume: 1, Issue:1

    Topics: Animals; Lysergic Acid Diethylamide; Male; Neurons; Piperazines; Pyrimidines; Raphe Nuclei; Rats; Rats, Inbred Strains; Serotonin; Serotonin Antagonists

1987
Further evidence that the serotonin receptor in the rat stomach fundus is not 5HT1A or 5HT1B.
    Life sciences, 1986, Jan-06, Volume: 38, Issue:1

    Topics: Animals; Brain Chemistry; Dose-Response Relationship, Drug; Gastric Fundus; Male; Mathematics; Muscle Contraction; Piperazines; Rats; Rats, Inbred Strains; Receptors, Serotonin; Serotonin; Serotonin Antagonists

1986