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1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine and gbr 12935

1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine has been researched along with gbr 12935 in 3 studies

Compound Research Comparison

Studies
(1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine)
Trials
(1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine)
Recent Studies (post-2010)
(1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine)
Studies
(gbr 12935)
Trials
(gbr 12935)
Recent Studies (post-2010) (gbr 12935)
62014203115

Protein Interaction Comparison

ProteinTaxonomy1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine (IC50)gbr 12935 (IC50)
Sodium-dependent noradrenaline transporter Homo sapiens (human)0.713
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.0038
Sodium-dependent serotonin transporterHomo sapiens (human)1.9995
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.4033
Small conductance calcium-activated potassium channel protein 2Rattus norvegicus (Norway rat)0.298
Small conductance calcium-activated potassium channel protein 3Rattus norvegicus (Norway rat)0.298
Small conductance calcium-activated potassium channel protein 1Rattus norvegicus (Norway rat)0.298
Sodium-dependent dopamine transporter Homo sapiens (human)0.018
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.017

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hoffman, BT; Katz, JL; Kopajtic, T; Newman, AH1
de Costa, B; Jacobson, AE; Reith, ME; Rice, KC1
Akunne, HC; Baumann, MH; Cadet, JL; Carroll, FI; Char, GU; de Costa, BR; Dersch, CM; Partilla, JS; Rice, KC; Rothman, RB1

Other Studies

3 other study(ies) available for 1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine and gbr 12935

ArticleYear
2D QSAR modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors.
    Journal of medicinal chemistry, 2000, Nov-02, Volume: 43, Issue:22

    Topics: Algorithms; Binding, Competitive; Carrier Proteins; Databases, Factual; Dopamine; Dopamine Plasma Membrane Transport Proteins; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Nerve Tissue Proteins; Quantitative Structure-Activity Relationship; Radioligand Assay; Reproducibility of Results; Software

2000
Evidence for mutually exclusive binding of cocaine, BTCP, GBR 12935, and dopamine to the dopamine transporter.
    European journal of pharmacology, 1992, Dec-01, Volume: 227, Issue:4

    Topics: Animals; Binding Sites; Binding, Competitive; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; Phencyclidine; Piperazines; Rats; Rats, Sprague-Dawley

1992
Studies of the biogenic amine transporters. III. Demonstration of two binding sites for [3H]GBR12935 and [3H]BTCP in rat caudate membranes.
    The Journal of pharmacology and experimental therapeutics, 1994, Volume: 268, Issue:3

    Topics: Animals; Binding Sites; Biogenic Amines; Carrier Proteins; Caudate Nucleus; Dopamine Agents; Ligands; Male; Membranes; Oxidopamine; Phencyclidine; Piperazines; Rats; Rats, Sprague-Dawley; Tritium

1994