1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine has been researched along with cocaine in 17 studies
| Studies (1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine) | Trials (1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine) | Recent Studies (post-2010) (1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine) | Studies (cocaine) | Trials (cocaine) | Recent Studies (post-2010) (cocaine) |
|---|---|---|---|---|---|
| 62 | 0 | 14 | 32,461 | 1,096 | 9,400 |
| Protein | Taxonomy | 1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine (IC50) | cocaine (IC50) |
|---|---|---|---|
| Amyloid-beta precursor protein | Homo sapiens (human) | 0.338 | |
| Fatty acid-binding protein, heart | Homo sapiens (human) | 0.367 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0855 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0855 | |
| D | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2B adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2C adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Alpha-2A adrenergic receptor | Rattus norvegicus (Norway rat) | 5.7544 | |
| Sodium-dependent noradrenaline transporter | Homo sapiens (human) | 1.2861 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.4321 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.0855 | |
| Sodium-dependent serotonin transporter | Homo sapiens (human) | 0.5442 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.8885 | |
| Sodium-dependent dopamine transporter | Homo sapiens (human) | 0.3796 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 5.541 | |
| Sodium-dependent dopamine transporter | Mus musculus (house mouse) | 0.2 | |
| Sigma non-opioid intracellular receptor 1 | Homo sapiens (human) | 1.05 | |
| Transporter | Rattus norvegicus (Norway rat) | 3.2277 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (64.71) | 18.2507 |
| 2000's | 6 (35.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Boja, JW; Carroll, FI; Kuhar, MJ; Lewin, AH | 1 |
| de Costa, BR; Eldefrawi, ME; He, XS; Mattson, MV; Raymon, LP | 1 |
| de Costa, BR; Eldefrawi, ME; He, X; Mattson, MV; Raymon, LP | 1 |
| de Costa, B; Jacobson, AE; Reith, ME; Rice, KC | 1 |
| Carroll, FI; De Costa, BR; Grieg, N; Kim, A; Pert, A; Rice, KC; Rothman, RB | 1 |
| Akunne, H; deCosta, BR; Jacobson, AE; Rice, KC; Rothman, RR | 1 |
| Barbanel, G; Kamenka, JM; Maurice, T; Vignon, J | 1 |
| Alburges, ME; Narang, N; Wamsley, JK | 1 |
| Barbanel, G; Maurice, T; Vignon, J | 1 |
| Kamenka, JM; Kleven, MS; Koek, W; Prinssen, EP; Vignon, J | 1 |
| Kamenka, JM; Kleven, MS; Koek, W; Vignon, J | 1 |
| Ben-Shahar, O; Martin-Fardon, R; Weiss, F | 1 |
| Martin-Fardon, R; Weiss, F | 1 |
| Deleuze-Masquefa, C; Kamenka, JM; Kerr, TM; Martin-Fardon, R; Weiss, F | 1 |
| Kamenka, JM; Lorentz, CU; Martin-Fardon, R; Weiss, F | 1 |
| Lorentz, CU; Martin-Fardon, R; Stuempfig, ND; Weiss, F | 1 |
| Bresee, CJ; Pechnick, RN; Poland, RE | 1 |
1 review(s) available for 1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine and cocaine
| Article | Year |
|---|---|
Cocaine receptor: biochemical characterization and structure-activity relationships of cocaine analogues at the dopamine transporter.
Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Receptors, Drug; Stereoisomerism; Structure-Activity Relationship | 1992 |
16 other study(ies) available for 1-(1-(2-benzo(b)thienyl)cyclohexyl)piperidine and cocaine
| Article | Year |
|---|---|
Synthesis and biological evaluation of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine homologues at dopamine-uptake and phencyclidine- and sigma-binding sites.
Topics: Animals; Cocaine; Dopamine; Dopamine Agents; Dopamine Antagonists; Guinea Pigs; Male; Molecular Structure; Phencyclidine; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Phencyclidine; Receptors, sigma | 1993 |
Further studies of the structure-activity relationships of 1-[1-(2-benzo[b]thienyl)cyclohexyl]piperidine. Synthesis and evaluation of 1-(2-benzo[b]thienyl)-N,N-dialkylcyclohexylamines at dopamine uptake and phencyclidine binding sites.
Topics: Animals; Binding Sites; Cocaine; Cyclohexylamines; Dopamine; Dopamine Antagonists; Phencyclidine; Piperidines; Rats; Structure-Activity Relationship | 1993 |
Evidence for mutually exclusive binding of cocaine, BTCP, GBR 12935, and dopamine to the dopamine transporter.
Topics: Animals; Binding Sites; Binding, Competitive; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Female; Phencyclidine; Piperazines; Rats; Rats, Sprague-Dawley | 1992 |
Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter.
Topics: Animals; Brain; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Membrane Glycoproteins; Membrane Transport Proteins; Motor Activity; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Nomifensine; Phencyclidine; Piperazines; Rats; Rats, Sprague-Dawley; Stereotyped Behavior | 1992 |
Synthesis and evaluation of novel BTCP based affinity ligands for the dopamine reuptake complex.
Topics: Animals; Binding, Competitive; Cocaine; Dopamine; Dopamine Agents; Guinea Pigs; In Vitro Techniques; Ligands; Phencyclidine; Receptors, Dopamine | 1990 |
Modulation by dopamine of [3H]N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine ([3H]BTCP, a phencyclidine derivative) binding to the dopamine uptake complex.
Topics: alpha-Methyltyrosine; Animals; Benserazide; Cocaine; Corpus Striatum; Dopamine; Dopamine Agents; Dopamine Plasma Membrane Transport Proteins; Haloperidol; In Vitro Techniques; Levodopa; Male; Membrane Proteins; Methyltyrosines; Mice; Nerve Tissue Proteins; Phencyclidine; Piperazines; Rats; Reserpine | 1991 |
Alterations in the dopaminergic receptor system after chronic administration of cocaine.
Topics: Animals; Benzazepines; Brain Chemistry; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Male; Phencyclidine; Raclopride; Rats; Receptors, Dopamine; Receptors, Dopamine D1; Receptors, Dopamine D2; Salicylamides; Up-Regulation | 1993 |
Endogenous dopamine differently affects N-[1-(2-benzo(b)thiophenyl)cyclohexyl]piperidine and cocaine binding to the dopamine uptake complex.
Topics: 4-Butyrolactone; Animals; Cocaine; Corpus Striatum; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Male; Membrane Proteins; Mice; Nerve Tissue Proteins; Phencyclidine; Piperazines | 1993 |
Does crossing over repeated treatment with the dopamine reuptake inhibitors cocaine and BTCP modify their effects on cocaine-induced locomotion?
Topics: Animals; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Interactions; Injections, Intraperitoneal; Male; Mice; Mice, Inbred C57BL; Motor Activity; Phencyclidine | 1999 |
Pharmacological characterization of the discriminative stimulus properties of the phencyclidine analog, N-[1-(2-benzo(b)thiophenyl)-cyclohexyl]piperidine.
Topics: Animals; Cocaine; Discrimination Learning; Dopamine Uptake Inhibitors; Male; Norepinephrine; Phencyclidine; Prazosin; Rats; Rats, Sprague-Dawley; Selective Serotonin Reuptake Inhibitors | 1999 |
Non reciprocal cross-sensitization between cocaine and BTCP on locomotor activity in the rat.
Topics: Animals; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Drug Interactions; Male; Motor Activity; Phencyclidine; Rats; Rats, Wistar | 2000 |
N-[1-(2-benzo[b]thiophenyl)Cyclohexyl]- piperidine (BTCP) exerts cocaine-like actions on drug-maintained responding in rats.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drinking Behavior; Injections, Intraperitoneal; Male; Phencyclidine; Rats; Rats, Wistar; Reinforcement, Psychology; Self Administration; Substance-Related Disorders | 2000 |
Behavioral and neurochemical effects of 3-OH-pip-BTCP, an active metabolite of BTCP in rats.
Topics: Animals; Behavior, Animal; Cocaine; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Microdialysis; Motor Activity; Phencyclidine; Rats; Rats, Wistar | 2001 |
3-OH-pip-BTCP, a metabolite of the potent DA uptake blocker BTCP, exerts cocaine-like action in rats.
Topics: Animals; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Male; Phencyclidine; Rats; Rats, Wistar; Self Administration | 2003 |
Priming with BTCP, a dopamine reuptake blocker, reinstates cocaine-seeking and enhances cocaine cue-induced reinstatement.
Topics: Animals; Cocaine; Conditioning, Operant; Dopamine Uptake Inhibitors; Male; Motivation; Phencyclidine; Rats | 2005 |
The role of antagonism of NMDA receptor-mediated neurotransmission and inhibition of the dopamine reuptake in the neuroendocrine effects of phencyclidine.
Topics: Adrenocorticotropic Hormone; Animals; Binding Sites; Binding, Competitive; Cocaine; Corticosterone; Dopamine Agonists; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Excitatory Amino Acid Antagonists; Male; Neuroprotective Agents; Phencyclidine; Prolactin; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate | 2006 |