1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine has been researched along with thiazoles in 14 studies
| Studies (1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine) | Trials (1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine) | Recent Studies (post-2010) (1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine) | Studies (thiazoles) | Trials (thiazoles) | Recent Studies (post-2010) (thiazoles) |
|---|---|---|---|---|---|
| 15 | 0 | 6 | 33,179 | 2,100 | 12,330 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 4 (28.57) | 29.6817 |
| 2010's | 7 (50.00) | 24.3611 |
| 2020's | 1 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Ishikawa, T; Motoyama, Y; Sakai, H; Takasugi, H; Tanaka, A | 1 |
| Dohi, M; Fujisaki, J; Motoyama, Y; Namikawa, Y; Sakata, Y; Seki, J; Takasugi, H; Tanaka, A; Yoshida, K | 1 |
| Goto, T; Motoyama, Y; Ochi, T | 1 |
| Goto, T; Ochi, T | 1 |
| Edwards, RM; Evans, C; Hieble, JP; McCafferty, GP; Wibberley, A | 1 |
| Dahlén, SE; Kumlin, M; Låstbom, L; Ryrfeldt, A; Selg, E | 1 |
| Borda, E; Busch, L; Miozza, V; S-Borda, L | 1 |
| Cho, SG; Choi, HY; Jeong, HS; Kim, JH; Lee, ER | 1 |
| Kim, KA; Kim, SH; Lee, YA; Min, A; Nam, YH; Shin, MH; Song, KJ | 1 |
| Gao, W; Li, J; Lu, J; Morales, A; Xing, J | 1 |
| García, M; López, C; Martín, ML; Morán, A; Restrepo, B; San Román, L | 1 |
| Jansson, L; Sandberg, M | 1 |
| Adams, C; Bazzigaluppi, P; Carlen, P; Janik, R; Koletar, M; Lake, EMR; McLaurin, J; Mester, J; Stanisz, GJ; Stefanovic, B; Thomason, LA | 1 |
| Aalkjaer, C; Chen, H; Simonsen, U | 1 |
14 other study(ies) available for 1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and thiazoles
| Article | Year |
|---|---|
Antiplatelet agents based on cyclooxygenase inhibition without ulcerogenesis. Evaluation and synthesis of 4,5-bis(4-methoxyphenyl)-2-substituted-thiazoles.
Topics: Animals; Blood Platelets; Cyclooxygenase Inhibitors; Guinea Pigs; Male; Malondialdehyde; Molecular Structure; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Rabbits; Rats; Rats, Sprague-Dawley; Stomach Ulcer; Structure-Activity Relationship; Thiazoles; Vasodilation | 1994 |
The anti-platelet actions of FR122047, a novel cyclooxygenase inhibitor.
Topics: Animals; Aspirin; Blood Platelets; Cyclooxygenase Inhibitors; Guinea Pigs; Humans; In Vitro Techniques; Irritants; Male; Malondialdehyde; Microsomes; Piperazines; Platelet Aggregation; Platelet Aggregation Inhibitors; Prostaglandins; Rabbits; Rats; Rats, Sprague-Dawley; Seminal Vesicles; Sheep; Stomach Ulcer; Thiazoles | 1993 |
The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models.
Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Formaldehyde; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Mice; Nitrobenzenes; Pain Measurement; Piperazines; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazoles | 2000 |
Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis.
Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; Chronic Disease; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Edema; Female; Hindlimb; Isoenzymes; Membrane Proteins; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Thiazoles; Thromboxane B2 | 2002 |
Dual, but not selective, COX-1 and COX-2 inhibitors, attenuate acetic acid-evoked bladder irritation in the anaesthetised female cat.
Topics: Acetic Acid; Anesthesia; Animals; Cats; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Indomethacin; Ketoprofen; Male; Nitrobenzenes; Piperazines; Reflex, Abnormal; Sodium Chloride; Sulfonamides; Thiazoles; Urinary Bladder Diseases | 2006 |
Effects of selective and non-selective COX inhibitors on antigen-induced release of prostanoid mediators and bronchoconstriction in the isolated perfused and ventilated guinea pig lung.
Topics: Animals; Bronchoconstriction; Celecoxib; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Diclofenac; Flurbiprofen; Guinea Pigs; Humans; Leukotrienes; Lung; Male; Ovalbumin; Piperazines; Prostaglandins; Pyrazoles; Sulfonamides; Thiazoles; Thromboxane A2; Thromboxane B2 | 2008 |
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.
Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles | 2010 |
Induction of cell growth arrest and apoptotic cell death in human breast cancer MCF-7 cells by the COX-1 inhibitor FR122047.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Apoptosis; Breast Neoplasms; Carcinoma in Situ; Cell Death; Cell Line, Tumor; Cell Proliferation; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Drug Evaluation, Preclinical; Female; Humans; Isoxazoles; Piperazines; Sulfonamides; Thiazoles | 2010 |
Leukotriene B(4) receptors BLT1 and BLT2 are involved in interleukin-8 production in human neutrophils induced by Trichomonas vaginalis-derived secretory products.
Topics: Benzoquinones; Endopeptidase K; Fatty Alcohols; Glycols; Hot Temperature; Humans; Interleukin-8; Leukotriene Antagonists; Leukotriene B4; Lipase; Lipoxygenase Inhibitors; Neutrophil Activation; Neutrophils; Piperazines; Receptors, Leukotriene B4; Tetrazoles; Thiazoles; Trichomonas Infections; Trichomonas vaginalis | 2012 |
Muscle cyclo-oxygenase-2 pathway contributes to the exaggerated muscle mechanoreflex in rats with congestive heart failure.
Topics: Animals; Blood Pressure; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Heart Failure; Heart Rate; Kidney; Male; Membrane Proteins; Muscle Contraction; Muscle, Skeletal; Myocardial Infarction; Piperazines; Pyrazoles; Rats; Rats, Sprague-Dawley; Reflex, Stretch; Sulfonamides; Sympathetic Nervous System; Thiazoles | 2012 |
The cyclooxygenase and nitric oxide synthesis/pathways mediate the inhibitory serotonergic response to the pressor effect elicited by sympathetic stimulation in long-term diabetic pithed rats.
Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Alloxan; Animals; Blood Pressure; Diabetes Mellitus, Experimental; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Oxadiazoles; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Serotonin; Signal Transduction; Sympathetic Nervous System; Thiazoles | 2012 |
Effects of cyclooxygenase inhibition on insulin release and pancreatic islet blood flow in rats.
Topics: Animals; Blood Flow Velocity; Blood Glucose; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Duodenum; Glucose; Indomethacin; Insulin; Islets of Langerhans; Lactones; Male; Membrane Proteins; Piperazines; Pyrazoles; Rats; Rats, Wistar; Regional Blood Flow; Sulfones; Thiazoles | 2014 |
Modulation of the peri-infarct neurogliovascular function by delayed COX-1 inhibition.
Topics: Animals; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Disease Models, Animal; Endothelin-1; Ischemia; Macrophages; Magnetic Resonance Imaging; Male; Membrane Proteins; Microglia; Neuroglia; Neurons; Perfusion; Piperazines; Rats; Rats, Sprague-Dawley; Spin Labels; Stroke; Thiazoles | 2017 |
A sex-specific, COX-derived/thromboxane receptor activator causes depolarization and vasoconstriction in male mice mesenteric resistance arteries.
Topics: Animals; Bridged Bicyclo Compounds, Heterocyclic; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Diabetes Mellitus, Experimental; Endothelium, Vascular; Fatty Acids, Unsaturated; Female; Hydrazines; Indomethacin; Male; Membrane Potentials; Mesenteric Arteries; Mice; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Obesity; Piperazines; Receptors, Thromboxane; Sex Characteristics; Thiazoles; Vascular Resistance; Vasoconstriction; Vasodilation | 2020 |