Compounds > 1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine
Page last updated: 2024-09-05

1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and rofecoxib

1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine has been researched along with rofecoxib in 1 studies

Compound Research Comparison

Studies
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)		Trials
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)		Recent Studies (post-2010)
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)		Studies
(rofecoxib)		Trials
(rofecoxib)		Recent Studies (post-2010) (rofecoxib)
15061,914307163

Protein Interaction Comparison

ProteinTaxonomy1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine (IC50)rofecoxib (IC50)
Prostaglandin G/H synthase 2 Bos taurus (cattle)0.43
Cytochrome c oxidase subunit 2Homo sapiens (human)1.51
Prostaglandin G/H synthase 1Ovis aries (sheep)0.5
Seed linoleate 13S-lipoxygenase-1Glycine max (soybean)0.5
Calpain-2 catalytic subunitHomo sapiens (human)0.02
Prostaglandin G/H synthase 1Homo sapiens (human)1.8
Prostaglandin G/H synthase 2Homo sapiens (human)0.3602
Prostaglandin G/H synthase 2 Rattus norvegicus (Norway rat)0.76
Prostaglandin G/H synthase 2Ovis aries (sheep)0.486
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.036
Sodium-dependent serotonin transporterMacaca mulatta (Rhesus monkey)0.5

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jansson, L; Sandberg, M1

Other Studies

1 other study(ies) available for 1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and rofecoxib

ArticleYear
Effects of cyclooxygenase inhibition on insulin release and pancreatic islet blood flow in rats.
    Upsala journal of medical sciences, 2014, Volume: 119, Issue:4

    Topics: Animals; Blood Flow Velocity; Blood Glucose; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Duodenum; Glucose; Indomethacin; Insulin; Islets of Langerhans; Lactones; Male; Membrane Proteins; Piperazines; Pyrazoles; Rats; Rats, Wistar; Regional Blood Flow; Sulfones; Thiazoles

2014