Page last updated: 2024-09-05

1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and nimesulide

1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine has been researched along with nimesulide in 1 studies

Compound Research Comparison

Studies
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)
Trials
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)
Recent Studies (post-2010)
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)
Studies
(nimesulide)
Trials
(nimesulide)
Recent Studies (post-2010) (nimesulide)
15061,272200271

Protein Interaction Comparison

ProteinTaxonomy1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine (IC50)nimesulide (IC50)
MyeloperoxidaseHomo sapiens (human)2.1
Prostaglandin G/H synthase 1Ovis aries (sheep)6.2
Procathepsin LHomo sapiens (human)1.92
Leukotriene A-4 hydrolaseHomo sapiens (human)0.023
Prostaglandin G/H synthase 1Homo sapiens (human)2.493
Prostaglandin G/H synthase 2Homo sapiens (human)1.8947
Prostaglandin G/H synthase 2Ovis aries (sheep)1.16

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Edwards, RM; Evans, C; Hieble, JP; McCafferty, GP; Wibberley, A1

Other Studies

1 other study(ies) available for 1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and nimesulide

ArticleYear
Dual, but not selective, COX-1 and COX-2 inhibitors, attenuate acetic acid-evoked bladder irritation in the anaesthetised female cat.
    British journal of pharmacology, 2006, Volume: 148, Issue:2

    Topics: Acetic Acid; Anesthesia; Animals; Cats; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Indomethacin; Ketoprofen; Male; Nitrobenzenes; Piperazines; Reflex, Abnormal; Sodium Chloride; Sulfonamides; Thiazoles; Urinary Bladder Diseases

2006