Page last updated: 2024-09-05

1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine has been researched along with n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide in 2 studies

Compound Research Comparison

Studies
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)
Trials
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)
Recent Studies (post-2010)
(1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)
Studies
(n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
Trials
(n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
Recent Studies (post-2010) (n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide)
15061,2203229

Protein Interaction Comparison

ProteinTaxonomy1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine (IC50)n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide (IC50)
Prostaglandin E synthaseHomo sapiens (human)10
Prostaglandin G/H synthase 1Ovis aries (sheep)2.1
AromataseHomo sapiens (human)0.68
Prostaglandin G/H synthase 1Mus musculus (house mouse)1.67
Prostaglandin G/H synthase 1Homo sapiens (human)3
Prostaglandin G/H synthase 2Homo sapiens (human)0.9037
Prostaglandin G/H synthase 2Ovis aries (sheep)2.4333
Prostaglandin G/H synthase 2Mus musculus (house mouse)0.1522
Carboxypeptidase B2Homo sapiens (human)1.8
Prostaglandin E synthaseMus musculus (house mouse)0.007

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goto, T; Motoyama, Y; Ochi, T1
Edwards, RM; Evans, C; Hieble, JP; McCafferty, GP; Wibberley, A1

Other Studies

2 other study(ies) available for 1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and n-(2-cyclohexyloxy-4-nitrophenyl)methanesulfonamide

ArticleYear
The analgesic effect profile of FR122047, a selective cyclooxygenase-1 inhibitor, in chemical nociceptive models.
    European journal of pharmacology, 2000, Mar-10, Volume: 391, Issue:1-2

    Topics: Acetic Acid; Analgesics; Animals; Behavior, Animal; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Formaldehyde; Humans; Indomethacin; Isoenzymes; Male; Membrane Proteins; Mice; Nitrobenzenes; Pain Measurement; Piperazines; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Rats; Rats, Sprague-Dawley; Sulfonamides; Thiazoles

2000
Dual, but not selective, COX-1 and COX-2 inhibitors, attenuate acetic acid-evoked bladder irritation in the anaesthetised female cat.
    British journal of pharmacology, 2006, Volume: 148, Issue:2

    Topics: Acetic Acid; Anesthesia; Animals; Cats; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Female; Indomethacin; Ketoprofen; Male; Nitrobenzenes; Piperazines; Reflex, Abnormal; Sodium Chloride; Sulfonamides; Thiazoles; Urinary Bladder Diseases

2006