1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and dinoprostone

1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine has been researched along with dinoprostone in 2 studies

Compound Research Comparison

Studies (1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)	Trials (1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)	Recent Studies (post-2010) (1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine)	Studies (dinoprostone)	Trials (dinoprostone)	Recent Studies (post-2010) (dinoprostone)
15	0	6	29,105	1,346	6,357

Protein Interaction Comparison

Protein	Taxonomy	dinoprostone (IC50)
Prostaglandin E2 receptor EP1 subtype	Homo sapiens (human)	0.0155
Prostaglandin E2 receptor EP4 subtype	Homo sapiens (human)	0.0031
Prostaglandin E2 receptor EP4 subtype	Rattus norvegicus (Norway rat)	0.0021
Prostaglandin E2 receptor EP3 subtype	Homo sapiens (human)	0.002
Prostaglandin E2 receptor EP2 subtype	Homo sapiens (human)	0.0087
Prostacyclin receptor	Homo sapiens (human)	0.26
Prostaglandin E2 receptor EP2 subtype	Rattus norvegicus (Norway rat)	0.0052

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Goto, T; Ochi, T	1
Borda, E; Busch, L; Miozza, V; S-Borda, L	1

Other Studies

2 other study(ies) available for 1-((4,5-bis(4-methoxyphenyl)-2-thiazoyl)carbonyl)-4-methylpiperazine and dinoprostone

Article	Year
Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis. British journal of pharmacology, 2002, Volume: 135, Issue:3 Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; Chronic Disease; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Edema; Female; Hindlimb; Isoenzymes; Membrane Proteins; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Thiazoles; Thromboxane B2	2002
Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis. Oral diseases, 2010, Volume: 16, Issue:8 Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles	2010

Article

Year

Differential effect of FR122047, a selective cyclo-oxygenase-1 inhibitor, in rat chronic models of arthritis.

British journal of pharmacology, 2002, Volume: 135, Issue:3

Topics: Adjuvants, Immunologic; Animals; Arthritis, Experimental; Chronic Disease; Collagen; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Dinoprostone; Dose-Response Relationship, Drug; Edema; Female; Hindlimb; Isoenzymes; Membrane Proteins; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred Lew; Thiazoles; Thromboxane B2

2002

Increase nitric oxide synthase activity in parotid glands from rats with experimental periodontitis.

Oral diseases, 2010, Volume: 16, Issue:8

Topics: Adenine; Amylases; Animals; Calcium; Cyclic AMP-Dependent Protein Kinase Catalytic Subunits; Cyclooxygenase Inhibitors; Dinoprostone; Disease Models, Animal; Egtazic Acid; Enzyme Inhibitors; Guanidines; Indazoles; Indomethacin; Male; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; omega-N-Methylarginine; Organ Size; Ornithine; Parotid Gland; Periodontitis; Piperazines; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar; Salivary Proteins and Peptides; Thiazoles

2010