1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with zidovudine in 4 studies
| Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Studies (zidovudine) | Trials (zidovudine) | Recent Studies (post-2010) (zidovudine) |
|---|---|---|---|---|---|
| 7,666 | 0 | 1,658 | 10,180 | 1,399 | 1,188 |
| Protein | Taxonomy | 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50) | zidovudine (IC50) |
|---|---|---|---|
| Thymidine kinase, cytosolic | Homo sapiens (human) | 3 | |
| Reverse transcriptase/RNaseH | Human immunodeficiency virus 1 | 0.6633 | |
| Protease | Human immunodeficiency virus 1 | 0.015 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Biondi, R; Bourdais, J; Guerreiro, C; Janin, J; Lascu, I; Sarfati, S; Véron, M | 1 |
| Biondi, R; Janin, J; Moréra, S; Sarfati, S; Sellam, O; Véron, M; Xu, Y | 1 |
| Deville-Bonne, D; Janin, J; Sarfati, R; Schneider, B; Sellam, O; Veron, M; Xu, YW | 1 |
| Dabernat, S; Gonin, P; Janin, J; Kumar, R; Lacombe, ML; Lascu, I; Milon, L; Morr, M; Xu, Y | 1 |
4 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and zidovudine
| Article | Year |
|---|---|
Cellular phosphorylation of anti-HIV nucleosides. Role of nucleoside diphosphate kinase.
Topics: Animals; Antiviral Agents; Binding Sites; Dictyostelium; Dideoxyadenosine; Dideoxynucleosides; Humans; Kinetics; Nucleoside-Diphosphate Kinase; Recombinant Proteins; Structure-Activity Relationship; Substrate Specificity; Zidovudine | 1996 |
X-ray analysis of azido-thymidine diphosphate binding to nucleoside diphosphate kinase.
Topics: Animals; Binding Sites; Crystallography, X-Ray; Dictyostelium; Diphosphates; Molecular Sequence Data; Nucleoside-Diphosphate Kinase; Zidovudine | 1997 |
Pre-steady state of reaction of nucleoside diphosphate kinase with anti-HIV nucleotides.
Topics: Animals; Anti-HIV Agents; Binding Sites; Deoxyribonucleotides; Dictyostelium; Dideoxynucleosides; Dideoxynucleotides; Kinetics; Models, Molecular; Mutagenesis, Site-Directed; Nucleoside-Diphosphate Kinase; Phosphorylation; Structure-Activity Relationship; Thymine Nucleotides; Zidovudine | 1998 |
Catalytic mechanism of nucleoside diphosphate kinase investigated using nucleotide analogues, viscosity effects, and X-ray crystallography.
Topics: Animals; Catalysis; Crystallography, X-Ray; Deoxyribonucleotides; Dictyostelium; Dideoxynucleosides; Kinetics; Models, Chemical; Nucleoside-Diphosphate Kinase; Structure-Activity Relationship; Thymine Nucleotides; Viscosity; Zidovudine | 1999 |