Compounds > 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone
Page last updated: 2024-09-03

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and wortmannin

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with wortmannin in 3 studies

Compound Research Comparison

Studies
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)		Trials
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)		Recent Studies (post-2010)
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)		Studies
(wortmannin)		Trials
(wortmannin)		Recent Studies (post-2010) (wortmannin)
7,66601,6584,0662726

Protein Interaction Comparison

ProteinTaxonomy1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50)wortmannin (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0465
Myosin light chain kinase, smooth muscleGallus gallus (chicken)0.26
Metabotropic glutamate receptor 1Rattus norvegicus (Norway rat)0.0085
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.2368
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.1309
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.0493
Serine/threonine-protein kinase mTORHomo sapiens (human)0.04
Phosphatidylinositol 4-kinase alphaHomo sapiens (human)0.28
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.0492
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4433
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.3567
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)0.019
Serine/threonine-protein kinase PLK3Homo sapiens (human)0.1057
Phosphatidylinositol 4-kinase betaHomo sapiens (human)0.44

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (66.67)18.2507
2000's1 (33.33)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hosaka, K; Kubohara, Y1
Bush, J; Cardelli, J; Knecht, D; Lee, E; Seastone, DJ1
Cardelli, JA; Grove, BD; Rodriguez-Paris, JM; Rupper, AC1

Other Studies

3 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and wortmannin

ArticleYear
The putative morphogen, DIF-1, of Dictyostelium discoideum activates Akt/PKB in human leukemia K562 cells.
    Biochemical and biophysical research communications, 1999, Oct-05, Volume: 263, Issue:3

    Topics: Androstadienes; Animals; Calcimycin; Calcium Channel Blockers; Cell Differentiation; Dictyostelium; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Gallic Acid; Hexanones; Humans; K562 Cells; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Structure-Activity Relationship; Thapsigargin; Wortmannin

1999
Overexpression of a novel rho family GTPase, RacC, induces unusual actin-based structures and positively affects phagocytosis in Dictyostelium discoideum.
    Molecular biology of the cell, 1998, Volume: 9, Issue:10

    Topics: Androstadienes; Animals; Cell Membrane; Dictyostelium; Enzyme Inhibitors; Exocytosis; GTP Phosphohydrolases; Hydrolases; Kinetics; Lysosomes; Microscopy, Confocal; Microscopy, Electron, Scanning; Phagocytosis; Phosphoinositide-3 Kinase Inhibitors; Pinocytosis; Wortmannin

1998
p110-related PI 3-kinases regulate phagosome-phagosome fusion and phagosomal pH through a PKB/Akt dependent pathway in Dictyostelium.
    Journal of cell science, 2001, Volume: 114, Issue:Pt 7

    Topics: Androstadienes; Animals; Chromones; Dictyostelium; Endosomes; Enzyme Inhibitors; Hydrogen-Ion Concentration; Lysosomes; Membrane Fusion; Morpholines; Phagosomes; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Signal Transduction; Wortmannin

2001