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1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and tretinoin

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with tretinoin in 5 studies

Compound Research Comparison

Studies
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Trials
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Recent Studies (post-2010)
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Studies
(tretinoin)
Trials
(tretinoin)
Recent Studies (post-2010) (tretinoin)
7,66601,65823,6541,0836,085

Protein Interaction Comparison

ProteinTaxonomy1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50)tretinoin (IC50)
Bile salt export pumpHomo sapiens (human)10
Amyloid-beta precursor proteinHomo sapiens (human)0.18
Adenosine receptor A3Homo sapiens (human)5.275
Retinoic acid receptor alphaHomo sapiens (human)2.2542
60 kDa heat shock protein, mitochondrialHomo sapiens (human)5.3
Retinoic acid receptor betaHomo sapiens (human)0.7537
Retinoic acid receptor alphaMus musculus (house mouse)0.0057
Retinoic acid receptor gamma Homo sapiens (human)0.0064
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.275
Retinoic acid receptor gammaMus musculus (house mouse)0.004
Retinoic acid receptor betaMus musculus (house mouse)0.005
Mitogen-activated protein kinase 1Homo sapiens (human)0.576
Nuclear receptor ROR-alphaHomo sapiens (human)0.1995
Alpha-synucleinHomo sapiens (human)3
Cellular retinoic acid-binding protein 1Gallus gallus (chicken)0.5233
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.358
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.275
Retinoic acid receptor RXR-gammaHomo sapiens (human)0.35
Nuclear receptor ROR-gammaHomo sapiens (human)0.1995
10 kDa heat shock protein, mitochondrialHomo sapiens (human)5.3
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1Homo sapiens (human)0.82
60 kDa chaperonin Escherichia coli6.7
10 kDa chaperonin Escherichia coli6.7
Nuclear receptor ROR-betaHomo sapiens (human)0.1259

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (60.00)18.2507
2000's2 (40.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kubohara, Y1
Drainas, D; Georgiou, S; Papadimou, E; Tsambaos, D1
Kerszberg, M1
Dannat, K; Dingermann, T; Eger, K; Tillner, J; Weiss, M; Winckler, T1
Drainas, D; Magoulas, G; Papadimou, E; Papaioannou, D1

Reviews

1 review(s) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and tretinoin

ArticleYear
Morphogen propagation and action: towards molecular models.
    Seminars in cell & developmental biology, 1999, Volume: 10, Issue:3

    Topics: Activins; Animals; Biological Transport; Cell Communication; Dictyostelium; Diffusion; Drosophila; Inhibins; Models, Biological; Morphogenesis; Receptors, Cell Surface; Receptors, Retinoic Acid; Retinoid X Receptors; Signal Transduction; Transcription Factors; Transcription, Genetic; Tretinoin; Xenopus

1999

Other Studies

4 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and tretinoin

ArticleYear
DIF-1, putative morphogen of D. discoideum, suppresses cell growth and promotes retinoic acid-induced cell differentiation in HL-60.
    Biochemical and biophysical research communications, 1997, Jul-18, Volume: 236, Issue:2

    Topics: Animals; Calcium; Cell Differentiation; Cell Division; Cyclic AMP; Dictyostelium; Hexanones; HL-60 Cells; Humans; Tretinoin

1997
Inhibition of ribonuclease P activity by retinoids.
    The Journal of biological chemistry, 1998, Sep-18, Volume: 273, Issue:38

    Topics: Acitretin; Animals; Dictyostelium; Endoribonucleases; Isotretinoin; Kinetics; Retinoids; Ribonuclease P; RNA, Catalytic; RNA, Transfer, Ser; Schizosaccharomyces; Structure-Activity Relationship; Tretinoin; Vitamin A

1998
Effects of medicinal compounds on the differentiation of the eukaryotic microorganism dictyostelium discoideum: can this model be used as a screening test for reproductive toxicity in humans?
    Die Pharmazie, 2003, Volume: 58, Issue:3

    Topics: Animals; Culture Media; Dictyostelium; Diethylstilbestrol; Drug Evaluation, Preclinical; Gene Expression Regulation; Genes, Reporter; Models, Biological; Phenytoin; Reproduction; Teratogens; Thalidomide; Tretinoin

2003
Preparation of spermine conjugates with acidic retinoids with potent ribonuclease P inhibitory activity.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:6

    Topics: Animals; Dictyostelium; Dose-Response Relationship, Drug; Drug Design; Enzyme Inhibitors; Molecular Structure; Ribonuclease P; Spermine; Stereoisomerism; Tretinoin

2009