Compounds > 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone

Page last updated: 2024-09-03

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and thapsigargin

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with thapsigargin in 10 studies

Compound Research Comparison

Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Studies (thapsigargin)	Trials (thapsigargin)	Recent Studies (post-2010) (thapsigargin)
7,666	0	1,658	5,234	3	918

Protein Interaction Comparison

Protein	Taxonomy	1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50)	thapsigargin (IC50)
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	Oryctolagus cuniculus (rabbit)		0.002

Research

Studies (10)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	5 (50.00)	18.2507
2000's	4 (40.00)	29.6817
2010's	1 (10.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Kubohara, Y; Okamoto, K	1
Fisher, PR; Nebl, T; Schaap, P	1
Hosaka, K; Kubohara, Y	1
Arai, A; Gokan, N; Hosaka, K; Kubohara, Y	1
Giusti, C; Golstein, P; Harms, B; Kikuchi, H; Kubohara, Y; Luciani, MF; Oshima, Y	1
Gross, JD; Rooney, EK; Satre, M	1
Amagai, A; Itakura, R; Maeda, Y; Tanaka, Y	1
Malchow, D; Schaloske, R; Schlatterer, C	1
De Lozanne, A; Lusche, DF; Malchow, D; Schlatterer, C	1
Golstein, P; Kosta, A; Lam, D; Luciani, MF	1

Other Studies

10 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and thapsigargin

Article	Year
Cytoplasmic Ca2+ and H+ concentrations determine cell fate in Dictyostelium discoideum. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1994, Volume: 8, Issue:11 Topics: Animals; Calcium; Calcium-Transporting ATPases; Cell Differentiation; Cytoplasm; Dictyostelium; Dimethadione; Dose-Response Relationship, Drug; Hexanones; Hydrogen-Ion Concentration; Kinetics; Models, Biological; Signal Transduction; Terpenes; Thapsigargin	1994
A slow sustained increase in cytosolic Ca2+ levels mediates stalk gene induction by differentiation inducing factor in Dictyostelium. The EMBO journal, 1996, Oct-01, Volume: 15, Issue:19 Topics: Animals; Calcium; Calcium-Transporting ATPases; Chelating Agents; Cytosol; Dictyostelium; Egtazic Acid; Enzyme Inhibitors; Extracellular Matrix Proteins; Fungal Proteins; Gene Expression Regulation, Developmental; Hexanones; Hydroquinones; Protozoan Proteins; Recombinant Fusion Proteins; Thapsigargin; Transcriptional Activation	1996
The putative morphogen, DIF-1, of Dictyostelium discoideum activates Akt/PKB in human leukemia K562 cells. Biochemical and biophysical research communications, 1999, Oct-05, Volume: 263, Issue:3 Topics: Androstadienes; Animals; Calcimycin; Calcium Channel Blockers; Cell Differentiation; Dictyostelium; Enzyme Activation; Enzyme Inhibitors; Erythrocytes; Gallic Acid; Hexanones; Humans; K562 Cells; Phosphorylation; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-akt; Structure-Activity Relationship; Thapsigargin; Wortmannin	1999
Pharmacological evidence that stalk cell differentiation involves increases in the intracellular Ca(2+) and H(+) concentrations in Dictyostelium discoideum. Development, growth & differentiation, 2007, Volume: 49, Issue:3 Topics: Animals; Calcium; Cell Differentiation; Dictyostelium; Dimethadione; Enzyme Inhibitors; Hexanones; Hydrogen; Hydroquinones; Spores, Protozoan; Thapsigargin	2007
Atg1 allows second-signaled autophagic cell death in Dictyostelium. Autophagy, 2011, Volume: 7, Issue:5 Topics: Animals; Autophagy; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Dictyostelium; Enzyme Inhibitors; Hexanones; Ionophores; Models, Biological; Organisms, Genetically Modified; Protein Kinases; Signal Transduction; Thapsigargin	2011
Characterisation of an intracellular Ca2+ pump in Dictyostelium. Cell calcium, 1994, Volume: 16, Issue:6 Topics: Animals; Calcium; Calcium-Transporting ATPases; Cell Compartmentation; Centrifugation, Density Gradient; Dictyostelium; Fungal Proteins; Intracellular Membranes; Microsomes; Nigericin; Oxalates; Proton-Translocating ATPases; Protons; Protozoan Proteins; Terpenes; Thapsigargin; Vacuoles; Vanadates	1994
The signals for starvation response are transduced through elevated [Ca2+]i in Dictyostelium cells. Experimental cell research, 1998, May-01, Volume: 240, Issue:2 Topics: Animals; Calcium; Dictyostelium; Enzyme Inhibitors; Ionophores; Nigericin; Phosphorylation; Phosphotyrosine; Signal Transduction; Thapsigargin	1998
A Xestospongin C-sensitive Ca(2+) store is required for cAMP-induced Ca(2+) influx and cAMP oscillations in Dictyostelium. The Journal of biological chemistry, 2000, Mar-24, Volume: 275, Issue:12 Topics: Animals; Biological Transport; Calcium; Calcium Channel Blockers; Calcium Channels; Chemotaxis; Cyclic AMP; Dictyostelium; Inositol 1,4,5-Trisphosphate; Inositol 1,4,5-Trisphosphate Receptors; Macrocyclic Compounds; Oxazoles; Periodicity; Receptors, Cytoplasmic and Nuclear; Thapsigargin	2000
A fast Ca2+-induced Ca2+-release mechanism in Dictyostelium discoideum. Cell calcium, 2008, Volume: 43, Issue:6 Topics: Animals; Biological Clocks; Calcium; Calcium Channels; Calcium Signaling; Calmodulin; Cytosol; Dictyostelium; Endoplasmic Reticulum; Enzyme Inhibitors; Inositol 1,4,5-Trisphosphate Receptors; Light; Mutation; Photic Stimulation; Ryanodine Receptor Calcium Release Channel; Thapsigargin; Time Factors; Vacuoles	2008
The inositol 1,4,5-trisphosphate receptor is required to signal autophagic cell death. Molecular biology of the cell, 2008, Volume: 19, Issue:2 Topics: Animals; Apoptosis; Autophagy; Cyclosporine; Dictyostelium; Egtazic Acid; Genes, Protozoan; Inositol 1,4,5-Trisphosphate Receptors; Models, Biological; Mutagenesis, Insertional; Mutation; Necrosis; Protozoan Proteins; Signal Transduction; Thapsigargin	2008