1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with sirolimus in 9 studies
| Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Studies (sirolimus) | Trials (sirolimus) | Recent Studies (post-2010) (sirolimus) |
|---|---|---|---|---|---|
| 7,666 | 0 | 1,658 | 20,711 | 2,368 | 11,516 |
| Protein | Taxonomy | 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50) | sirolimus (IC50) |
|---|---|---|---|
| Bile salt export pump | Homo sapiens (human) | 10 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 1.25 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 2 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 2 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Mus musculus (house mouse) | 0.001 | |
| Cytochrome P450 2C19 | Homo sapiens (human) | 4 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.0897 | |
| Peptidyl-prolyl cis-trans isomerase FKBP1A | Homo sapiens (human) | 0.0042 | |
| Regulatory-associated protein of mTOR | Homo sapiens (human) | 0.225 | |
| Target of rapamycin complex subunit LST8 | Homo sapiens (human) | 0.225 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.9 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 1.1 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 7 (77.78) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, X; Kimmel, AR; Liao, XH; Majithia, A | 1 |
| Anjard, C; Loomis, WF; Manjithaya, R; Subramani, S | 1 |
| Bhandari, R; Huang, X; Khurana, T; Kimmel, AR; Majithia, A; Rosel, D | 1 |
| Callahan, J; Gerdes, K; Pflaum, K; Snyder, ML; Yovo, K | 1 |
| Lohia, R; Saran, S; Swer, PB | 1 |
| Cai, H; Devreotes, PN; Freyre, M; Hoeller, O; Huang, CH; Sun, Y; Toettcher, JE; Weiner, OD; Zhao, M | 1 |
| Annesley, SJ; Fisher, PR; Sen, MG; Smith, PK | 1 |
| Jaiswal, P; Khurana, T; Kimmel, AR; Liao, XH; Majithia, AR; Rosel, D | 1 |
| Brown, IN; Charest, PG; Collins, SE; Mouneimne, G; Mundo, MI; Swango, DJ; Werner, AN; Wiegand, ME | 1 |
2 review(s) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and sirolimus
| Article | Year |
|---|---|
Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism.
Topics: Amino Acid Sequence; Amino Acids; Animals; Arabidopsis Proteins; Dictyostelium; Models, Biological; Molecular Sequence Data; Phosphatidylinositol 3-Kinases; Phosphorylation; Proline; Protein Serine-Threonine Kinases; Ribosomal Protein S6 Kinases; Sequence Homology, Amino Acid; Signal Transduction; Sirolimus; Tacrolimus Binding Protein 1A; Transcription Factors | 2008 |
Integrated actions of mTOR complexes 1 and 2 for growth and development of Dictyostelium.
Topics: Adenylyl Cyclases; Cell Proliferation; Dictyostelium; Down-Regulation; GTP Phosphohydrolases; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Signal Transduction; Sirolimus; Up-Regulation | 2019 |
7 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and sirolimus
| Article | Year |
|---|---|
Unconventional secretion of Pichia pastoris Acb1 is dependent on GRASP protein, peroxisomal functions, and autophagosome formation.
Topics: Acyl Coenzyme A; Animals; Autophagy; Biological Assay; Cell Membrane; Dictyostelium; Fungal Proteins; Genes, Fungal; Intercellular Signaling Peptides and Proteins; Intracellular Membranes; Kinetics; Membrane Fusion; Models, Biological; Mutation; Nitrogen; Oxidation-Reduction; Peptides; Peroxisomes; Phagosomes; Pichia; Protein Processing, Post-Translational; Protein Transport; Sirolimus | 2010 |
TOR complex 2 (TORC2) in Dictyostelium suppresses phagocytic nutrient capture independently of TORC1-mediated nutrient sensing.
Topics: Adaptor Proteins, Signal Transducing; Animals; Cell Adhesion; Dictyostelium; Food; Mechanistic Target of Rapamycin Complex 1; Mechanistic Target of Rapamycin Complex 2; Multiprotein Complexes; Peptide Initiation Factors; Phagocytosis; Phosphorylation; Pinocytosis; Proto-Oncogene Proteins c-akt; Signal Transduction; Sirolimus; Time Factors; TOR Serine-Threonine Kinases | 2012 |
Lipopolysaccharide induction of autophagy is associated with enhanced bactericidal activity in Dictyostelium discoideum.
Topics: Anti-Bacterial Agents; Autophagy; Dictyostelium; Lipopolysaccharides; Phagosomes; Sirolimus; Staphylococcus aureus | 2012 |
Analysis of rapamycin induced autophagy in Dictyostelium discoideum.
Topics: Antioxidants; Autophagy; Calcium; Cell Survival; Cells, Cultured; Dictyostelium; G1 Phase; Oxidative Stress; Reactive Oxygen Species; Sirolimus | 2014 |
Gβ Regulates Coupling between Actin Oscillators for Cell Polarity and Directional Migration.
Topics: Actins; Biological Clocks; Cell Movement; Cell Polarity; Cytoskeleton; Dictyostelium; GTP-Binding Protein beta Subunits; Models, Biological; Signal Transduction; Sirolimus | 2016 |
Modelling of Neuronal Ceroid Lipofuscinosis Type 2 in
Topics: Aminopeptidases; Cell Line; Cell Proliferation; Dictyostelium; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; DNA, Antisense; DNA, Protozoan; Gene Expression; Gene Knockdown Techniques; Lysosomes; Mutation; Neuronal Ceroid-Lipofuscinoses; Optical Imaging; Phagocytosis; Phenotype; Phototaxis; Ras Homolog Enriched in Brain Protein; RNA, Messenger; Serine Proteases; Sirolimus; TOR Serine-Threonine Kinases; Tripeptidyl-Peptidase 1 | 2019 |
Ras-mediated activation of mTORC2 promotes breast epithelial cell migration and invasion.
Topics: Animals; Breast Neoplasms; Cell Movement; Dictyostelium; Epithelial Cells; Female; Humans; Mammals; Mechanistic Target of Rapamycin Complex 2; ras Proteins; Sirolimus | 2023 |