1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and risedronic acid

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with risedronic acid in 2 studies

Compound Research Comparison

Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Studies (risedronic acid)	Trials (risedronic acid)	Recent Studies (post-2010) (risedronic acid)
7,666	0	1,658	1,318	290	487

Protein Interaction Comparison

Protein	Taxonomy	risedronic acid (IC50)
Farnesyl pyrophosphate synthase	Homo sapiens (human)	0.1104
Farnesyl pyrophosphate synthase	Leishmania donovani	0.1699
Farnesyl diphosphate synthase	Toxoplasma gondii	0.074
Farnesyl diphosphate synthase	Trypanosoma cruzi	0.027

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Brown, RJ; Grove, JE; Watts, DJ	1
Blackburn, GM; Brown, RJ; Carran, J; Hounslow, AM; Rejman, D; Watts, DJ	1

Other Studies

2 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and risedronic acid

Article	Year
The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:5 Topics: Alendronate; Alkyl and Aryl Transferases; Amino Acid Sequence; Animals; Base Sequence; Bone Resorption; Dictyostelium; Diphosphonates; DNA Primers; Etidronic Acid; Farnesyl-Diphosphate Farnesyltransferase; Geranyltranstransferase; Molecular Sequence Data; Risedronic Acid; RNA, Messenger; Sequence Homology, Amino Acid	2000
Determination of the microscopic equilibrium dissociation constants for risedronate and its analogues reveals two distinct roles for the nitrogen atom in nitrogen-containing bisphosphonate drugs. Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14 Topics: Animals; Bone Density Conservation Agents; Dictyostelium; Diphosphonates; Etidronic Acid; Hydrogen-Ion Concentration; Microscopy; Nitrogen; Proteome; Risedronic Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Fast Atom Bombardment	2008

Article

Year

The intracellular target for the antiresorptive aminobisphosphonate drugs in Dictyostelium discoideum is the enzyme farnesyl diphosphate synthase.

Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2000, Volume: 15, Issue:5

Topics: Alendronate; Alkyl and Aryl Transferases; Amino Acid Sequence; Animals; Base Sequence; Bone Resorption; Dictyostelium; Diphosphonates; DNA Primers; Etidronic Acid; Farnesyl-Diphosphate Farnesyltransferase; Geranyltranstransferase; Molecular Sequence Data; Risedronic Acid; RNA, Messenger; Sequence Homology, Amino Acid

2000

Determination of the microscopic equilibrium dissociation constants for risedronate and its analogues reveals two distinct roles for the nitrogen atom in nitrogen-containing bisphosphonate drugs.

Journal of medicinal chemistry, 2008, Jul-24, Volume: 51, Issue:14

Topics: Animals; Bone Density Conservation Agents; Dictyostelium; Diphosphonates; Etidronic Acid; Hydrogen-Ion Concentration; Microscopy; Nitrogen; Proteome; Risedronic Acid; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Fast Atom Bombardment

2008