1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with methotrexate in 8 studies
| Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Studies (methotrexate) | Trials (methotrexate) | Recent Studies (post-2010) (methotrexate) |
|---|---|---|---|---|---|
| 7,666 | 0 | 1,658 | 41,593 | 5,666 | 11,969 |
| Protein | Taxonomy | 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50) | methotrexate (IC50) |
|---|---|---|---|
| Thymidylate synthase | Escherichia coli | 1.8 | |
| nuclear receptor coactivator 3 isoform a | Homo sapiens (human) | 0.211 | |
| Toll-like receptor 4 | Homo sapiens (human) | 1.04 | |
| Fatty-acid amide hydrolase 1 | Mus musculus (house mouse) | 0.08 | |
| Dihydrofolate reductase | Homo sapiens (human) | 0.0522 | |
| Dihydrofolate reductase | Mus musculus (house mouse) | 0.0331 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0348 | |
| Dihydrofolate reductase | Gallus gallus (chicken) | 0.0545 | |
| Dihydrofolate reductase | Enterococcus faecium | 0.0014 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.0138 | |
| Thymidylate synthase | Homo sapiens (human) | 0.343 | |
| 5-hydroxytryptamine receptor 2C | Rattus norvegicus (Norway rat) | 0.0147 | |
| Thymidylate synthase | Escherichia coli K-12 | 0.0181 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.1529 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.084 | |
| Folate receptor beta | Homo sapiens (human) | 0.1585 | |
| 5-hydroxytryptamine receptor 2A | Rattus norvegicus (Norway rat) | 0.0011 | |
| Cytochrome P450 11B1, mitochondrial | Bos taurus (cattle) | 0.0012 | |
| Folate receptor alpha | Homo sapiens (human) | 0.2263 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.0717 | |
| Histidine decarboxylase | Rattus norvegicus (Norway rat) | 0.0014 | |
| Trifunctional purine biosynthetic protein adenosine-3 | Homo sapiens (human) | 0.01 | |
| Bifunctional purine biosynthesis protein ATIC | Homo sapiens (human) | 0.01 | |
| Delta-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Mu-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Kappa-type opioid receptor | Rattus norvegicus (Norway rat) | 0.003 | |
| Reduced folate transporter | Homo sapiens (human) | 0.012 | |
| Dihydrofolate reductase | Mycobacterium tuberculosis H37Rv | 0.0174 | |
| Folylpolyglutamate synthase, mitochondrial | Homo sapiens (human) | 3.2 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 0.0547 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Trypanosoma cruzi | 0.11 | |
| Dihydrofolate reductase | Bacillus anthracis | 0.0136 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 0.0047 | |
| Proton-coupled folate transporter | Homo sapiens (human) | 0.1207 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bominaar, TA; Bulgakov, R; de Wit, RJ; Rinke de Wit, TF | 1 |
| Bulgakov, R; De Wit, RJ | 1 |
| Deering, RA; Michrina, CA | 1 |
| Frazier, WA; Nandini-Kishore, SG | 1 |
| Frazier, WA; Meyers, BL; Nandini-Kishore, SG | 1 |
| Burdine, V; Clarke, M | 1 |
| Blusch, JH; Nellen, W | 1 |
| Kimmel, AR; Meena, NP | 1 |
1 review(s) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and methotrexate
| Article | Year |
|---|---|
Chemotactic receptors of Dictyostelium discoideum.
Topics: Affinity Labels; Aminohydrolases; Animals; Carrier Proteins; Cell Membrane; Chemotaxis; Chemotaxis, Leukocyte; Cyclic AMP; Dictyostelium; Folate Receptors, GPI-Anchored; Methotrexate; Myxomycetes; Protozoan Proteins; Radioligand Assay; Receptors, Cell Surface; Receptors, Cyclic AMP; Receptors, Formyl Peptide; Solubility | 1982 |
7 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and methotrexate
| Article | Year |
|---|---|
Differential effects of stimulus termination on excitation and desensitization of folic acid receptors and guanylate cyclase in Dictyostelium discoideum.
Topics: Aminohydrolases; Carrier Proteins; Cyclic GMP; Dictyostelium; Folate Receptors, GPI-Anchored; Folic Acid; GTP-Binding Proteins; Guanylate Cyclase; Kinetics; Methotrexate; Protein Conformation; Protozoan Proteins; Receptors, Cell Surface | 1987 |
Guanine nucleotides modulate the ligand binding properties of cell surface folate receptors in Dictyostelium discoideum.
Topics: Binding, Competitive; Carrier Proteins; Cell Membrane; Dictyostelium; Folate Receptors, GPI-Anchored; Folic Acid; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Methotrexate; Receptors, Cell Surface | 1985 |
Inhibitors of DNA precursor metabolism in Dictyostelium discoideum.
Topics: Aminopterin; Antimetabolites; Dictyostelium; DNA; Floxuridine; Folic Acid; Hydroxyurea; Methotrexate; Time Factors; Trimethoprim | 1982 |
[3H]Methotrexate as a ligand for the folate receptor of Dictyostelium discoideum.
Topics: Carrier Proteins; Cell Aggregation; Chemotaxis; Cyclic AMP; Dictyostelium; Folate Receptors, GPI-Anchored; Kinetics; Ligands; Methotrexate; Receptors, Cell Surface; Structure-Activity Relationship | 1981 |
Genetic and physiologic modulation of the prestarvation response in Dictyostelium discoideum.
Topics: Aminopterin; Animals; Azaguanine; Biological Factors; Cell Adhesion Molecules; Cell Count; Cell Movement; Chemotactic Factors; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; Discoidins; Folic Acid; Fungal Proteins; Gene Expression Regulation; Gene Expression Regulation, Fungal; GTP-Binding Proteins; Klebsiella pneumoniae; Lectins; Methotrexate; Phosphoric Diester Hydrolases; Protozoan Proteins; Second Messenger Systems | 1995 |
Folate responsiveness during growth and development of Dictyostelium: separate but related pathways control chemotaxis and gene regulation.
Topics: Animals; Azaguanine; Blotting, Northern; Carrier Proteins; Chemotaxis; Dictyostelium; Discoidins; Folate Receptors, GPI-Anchored; Folic Acid; Fungal Proteins; Gene Expression; Gene Expression Regulation, Fungal; Lectins; Methotrexate; Protozoan Proteins; Receptors, Cell Surface; RNA, Fungal | 1994 |
Biochemical Responses to Chemically Distinct Chemoattractants During the Growth and Development of Dictyostelium.
Topics: Chemotactic Factors; Chemotaxis; Cyclic AMP; Dictyostelium; Extracellular Signal-Regulated MAP Kinases; Folic Acid; Mechanistic Target of Rapamycin Complex 2; Methotrexate; Phosphorylation; Protein Binding; Receptors, G-Protein-Coupled; Signal Transduction | 2016 |