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1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and guanosine diphosphate

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with guanosine diphosphate in 26 studies

Compound Research Comparison

Studies
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Trials
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Recent Studies (post-2010)
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Studies
(guanosine diphosphate)
Trials
(guanosine diphosphate)
Recent Studies (post-2010) (guanosine diphosphate)
7,66601,6584,4852672

Protein Interaction Comparison

ProteinTaxonomy1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50)guanosine diphosphate (IC50)
72 kDa type IV collagenaseHomo sapiens (human)2.3
MatrilysinHomo sapiens (human)2.3
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6Homo sapiens (human)2.3
Alpha-(1,3)-fucosyltransferase 7Homo sapiens (human)2.3
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1Homo sapiens (human)2.3

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19907 (26.92)18.7374
1990's14 (53.85)18.2507
2000's3 (11.54)29.6817
2010's1 (3.85)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Carlier, MF; Lascu, I; Melki, R; Véron, M1
Klein, C; Um, HD3
Ludérus, ME; Spijkers, MJ; Van Driel, R1
Anschutz, A; Klein, C1
Anschutz, A; Howlet, A; Klein, C1
Kesbeke, F; Snaar-Jagalska, BE; Van Haastert, PJ1
Kesbeke, F; Pupillo, M; Snaar-Jagalska, BE; Van Haastert, PJ1
de Wit, RJ; DeGoede, J; Janssens, PM; Kesbeke, F; van Haastert, PJ1
De Wit, RJ; Snaar-Jagalska, BE1
Janssens, PM; Snaar-Jagalska, BE; Van Haastert, PJ1
Bulgakov, R; De Wit, RJ1
Malchow, D; Schlatterer, C1
Browning, DD; Lewis, KE; O'Day, DH1
Bominaar, AA; Kesbeke, F; Van Haastert, PJ1
Bominaar, AA; Molijn, AC; Pestel, M; Van Haastert, PJ; Veron, M1
Anschutz, AL; Klein, C; Siegel, NR; Um, HD; Veron, M1
Huynh, A; Kozarov, E; Scott-Ward, T; Teng-umnuay, P; van der Wel, H; West, CM1
Birney, M; Klein, C; Um, H1
Bell, A; Condeelis, J; Edmonds, BT; Leyh, TS; Wyckoff, J1
Cervoni, L; Giartosio, A; Gonin, P; Janin, J; Lascu, I; Merouani, M; Morr, M; Xu, Y1
Devreotes, P; Sako, Y; Tanaka, T; Ueda, M; Yanagida, T1
Agarwal, M; Larochelle, DA; Nelson, DJ1
Avesson, L; Crona, M; Hinas, A; Klose, R; Lundin, D; Sahlin, M; Sjöberg, BM; Söderbom, F1
Arai, K; Iijima, M; Iwata, W; Murata, D; Senoo, H; Sesaki, H; Wai, M1

Other Studies

26 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and guanosine diphosphate

ArticleYear
Nucleoside diphosphate kinase does not directly interact with tubulin nor microtubules.
    Biochemical and biophysical research communications, 1992, Aug-31, Volume: 187, Issue:1

    Topics: Animals; Brain Chemistry; Dictyostelium; Guanosine Diphosphate; Guanosine Triphosphate; Humans; Kinetics; Macromolecular Substances; Microtubule-Associated Proteins; Microtubules; Nucleoside-Diphosphate Kinase; Phosphorylation; Polymers; Rabbits; Swine; Tubulin

1992
Dual role of GDP in the regulation of the levels of p36 phosphorylation in Dictyostelium discoideum.
    Journal of protein chemistry, 1991, Volume: 10, Issue:4

    Topics: Animals; Cell Membrane; Dictyostelium; Enzyme Activation; Guanosine Diphosphate; Membrane Proteins; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases; Sensitivity and Specificity

1991
Changes in cyclic AMP receptor properties during adaptation in Dictyostelium discoideum.
    Journal of cell science, 1990, Volume: 95 ( Pt 4)

    Topics: Adaptation, Physiological; Cell Cycle; Cell Membrane; Cyclic AMP; Dictyostelium; Freezing; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Nitrogen; Receptors, Cyclic AMP

1990
Characterization of a GDP-sensitive phosphorylation in plasma membranes of D. discoideum.
    Journal of protein chemistry, 1990, Volume: 9, Issue:4

    Topics: Adenosine Triphosphate; Binding Sites; Cell Membrane; Dictyostelium; Guanosine Diphosphate; Guanosine Triphosphate; Hydrogen-Ion Concentration; Membrane Proteins; Molecular Weight; Phosphoproteins; Phosphorylation; Protein Kinases; Substrate Specificity

1990
GDP stimulates the phosphorylation of a 36-kDa membrane protein in Dictyostelium discoideum.
    Proceedings of the National Academy of Sciences of the United States of America, 1989, Volume: 86, Issue:10

    Topics: Adenine Nucleotides; Blotting, Western; Cell Membrane; Dictyostelium; Fungal Proteins; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Membrane Proteins; Molecular Weight; Phosphoprotein Phosphatases; Phosphoproteins; Phosphorylation

1989
Signal transduction in Dictyostelium fgd A mutants with a defective interaction between surface cAMP receptors and a GTP-binding regulatory protein.
    The Journal of cell biology, 1988, Volume: 107, Issue:2

    Topics: Adenylyl Cyclases; Binding, Competitive; Chemotaxis; Cyclic AMP; Dictyostelium; Electrophoresis, Polyacrylamide Gel; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Immunoassay; Kinetics; Mutation; Receptors, Cyclic AMP; Thionucleotides

1988
Immunological detection of G-protein alpha-subunits in Dictyostelium discoideum.
    Biochemical and biophysical research communications, 1988, Oct-31, Volume: 156, Issue:2

    Topics: Blotting, Western; Cyclic AMP; Dictyostelium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Molecular Weight; Mutation; Receptors, Cyclic AMP; Thionucleotides

1988
G-protein-mediated interconversions of cell-surface cAMP receptors and their involvement in excitation and desensitization of guanylate cyclase in Dictyostelium discoideum.
    The Journal of biological chemistry, 1986, May-25, Volume: 261, Issue:15

    Topics: Cell Membrane; Cyclic AMP; Dictyostelium; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylate Cyclase; Kinetics; Mathematics; Receptors, Cyclic AMP; Tritium

1986
Folate and cAMP modulate GTP binding to isolated membranes of Dictyostelium discoideum. Functional coupling between cell surface receptors and G-proteins.
    Biochemical and biophysical research communications, 1985, May-31, Volume: 129, Issue:1

    Topics: Binding Sites; Calcium; Cyclic AMP; Dictyostelium; Folic Acid; GTP-Binding Proteins; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics

1985
The regulation of adenylate cyclase by guanine nucleotides in Dictyostelium discoideum membranes.
    European journal of biochemistry, 1987, Jan-15, Volume: 162, Issue:2

    Topics: Adenylyl Cyclases; Cell Membrane; Cytosol; Dictyostelium; GTP-Binding Proteins; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Substrate Specificity

1987
Guanine nucleotides modulate the ligand binding properties of cell surface folate receptors in Dictyostelium discoideum.
    FEBS letters, 1985, Jan-07, Volume: 179, Issue:2

    Topics: Binding, Competitive; Carrier Proteins; Cell Membrane; Dictyostelium; Folate Receptors, GPI-Anchored; Folic Acid; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Methotrexate; Receptors, Cell Surface

1985
Intercellular guanosine-5'-0-(3-thiotriphosphate) blocks chemotactic motility of Dictyostelium discoideum amoebae.
    Cell motility and the cytoskeleton, 1993, Volume: 25, Issue:3

    Topics: Amoeba; Animals; Calcium; Cell Movement; Cells, Cultured; Chemotaxis; Cyclic AMP; Dextrans; Dictyostelium; Dose-Response Relationship, Drug; Egtazic Acid; Fluorescein-5-isothiocyanate; Fura-2; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Homeostasis; Second Messenger Systems; Thionucleotides; Vacuoles

1993
Regulatory role of GDP in the phosphoenzyme formation of guanine nucleotide: specific forms of succinyl coenzyme A synthetase.
    Journal of protein chemistry, 1994, Volume: 13, Issue:2

    Topics: Allosteric Regulation; Animals; Catalysis; Dictyostelium; Guanine Nucleotides; Guanosine Diphosphate; Guanosine Triphosphate; Kinetics; Phosphates; Phosphorylation; Succinate-CoA Ligases; Swine

1994
Signal transduction during cannibalistic sexual phagocytosis: calcium is not the trigger but GTP-binding protein function is essential.
    Cellular signalling, 1994, Volume: 6, Issue:2

    Topics: Animals; Blotting, Western; Calcium; Chemotaxis; Dictyostelium; Electrophoresis, Polyacrylamide Gel; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Phagocytosis; Signal Transduction; Thionucleotides; Zygote

1994
Evidence for allosteric regulation of succinyl-CoA synthetase.
    The Biochemical journal, 1993, Nov-01, Volume: 295 ( Pt 3)

    Topics: Allosteric Regulation; Animals; Binding Sites; Chromatography, Gel; Dictyostelium; Guanosine Diphosphate; Guanosine Triphosphate; Macromolecular Substances; Phosphorylation; Succinate-CoA Ligases

1993
Phospholipase C in Dictyostelium discoideum. Cyclic AMP surface receptor and G-protein-regulated activity in vitro.
    The Biochemical journal, 1994, Jan-01, Volume: 297 ( Pt 1)

    Topics: Animals; Calcium; Cyclic AMP; Dictyostelium; Egtazic Acid; Enzyme Activation; GTP-Binding Proteins; Guanine Nucleotides; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphatidylinositols; Receptors, Cyclic AMP; Thionucleotides; Tritium; Type C Phospholipases

1994
Activation of G-proteins by receptor-stimulated nucleoside diphosphate kinase in Dictyostelium.
    The EMBO journal, 1993, Volume: 12, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Cell Membrane; Cyclic AMP; Dictyostelium; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Diphosphate; Guanosine Triphosphate; Nucleoside-Diphosphate Kinase; Receptors, Cyclic AMP

1993
P36, a Dictyostelium discoideum protein whose phosphorylation is stimulated by GDP, is homologous to the alpha-subunit of succinyl-CoA synthetase.
    Biochimica et biophysica acta, 1993, Mar-05, Volume: 1162, Issue:1-2

    Topics: Adolescent; Alkylation; Amino Acid Sequence; Animals; Cricetinae; Dictyostelium; Fungal Proteins; Guanosine Diphosphate; Humans; Molecular Sequence Data; Oxidation-Reduction; Phosphorylation; Sequence Homology, Nucleic Acid; Succinate-CoA Ligases; Trypsin

1993
Purification and characterization of an alpha1,2,-L-fucosyltransferase, which modifies the cytosolic protein FP21,from the cytosol of Dictyostelium.
    The Journal of biological chemistry, 1996, May-17, Volume: 271, Issue:20

    Topics: Amino Acid Sequence; Animals; Chromatography, Gel; Cytosol; Dictyostelium; Fucosyltransferases; Galactoside 2-alpha-L-fucosyltransferase; Glycoproteins; Guanosine Diphosphate; Kinetics; Molecular Sequence Data

1996
Multiple levels of regulation of Escherichia coli succinyl-CoA synthetase.
    Archives of biochemistry and biophysics, 1997, Nov-01, Volume: 347, Issue:1

    Topics: Adenosine Diphosphate; Allosteric Site; Animals; Bacterial Proteins; Binding Sites; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Phosphorylation; Protein Denaturation; RNA-Binding Proteins; Succinate-CoA Ligases; Temperature

1997
The effect of F-actin on the binding and hydrolysis of guanine nucleotide by Dictyostelium elongation factor 1A.
    The Journal of biological chemistry, 1998, Apr-24, Volume: 273, Issue:17

    Topics: Actins; Animals; Dictyostelium; Glycerol; Guanosine Diphosphate; Guanosine Triphosphate; Hydrolysis; Kinetics; Peptide Elongation Factor 1; Peptide Elongation Factors; Protein Binding; Thermodynamics

1998
Binding of nucleotides to nucleoside diphosphate kinase: a calorimetric study.
    Biochemistry, 2001, Apr-17, Volume: 40, Issue:15

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Binding Sites; Calorimetry, Differential Scanning; Crystallography, X-Ray; Dictyostelium; Guanosine Diphosphate; Humans; Inosine Diphosphate; Myxococcus xanthus; Nucleoside-Diphosphate Kinase; Purine Nucleotides; Thermodynamics; Thymine Nucleotides; Titrimetry

2001
Single-molecule analysis of chemotactic signaling in Dictyostelium cells.
    Science (New York, N.Y.), 2001, Oct-26, Volume: 294, Issue:5543

    Topics: Animals; Carbocyanines; Cell Membrane; Chemotaxis; Cyclic AMP; Dictyostelium; Diffusion; Guanosine Diphosphate; Guanosine Triphosphate; Heterotrimeric GTP-Binding Proteins; Kinetics; Microscopy, Fluorescence; Mutation; Phosphorylation; Pseudopodia; Receptors, Cyclic AMP; Signal Transduction

2001
The three-dimensional model of Dictyostelium discoideum racE based on the human rhoA-GDP crystal structure.
    Journal of molecular graphics & modelling, 2002, Volume: 21, Issue:1

    Topics: Amino Acid Sequence; Animals; Binding Sites; Computer Simulation; Crystallography, X-Ray; Dictyostelium; Guanosine Diphosphate; Humans; Models, Molecular; Molecular Sequence Data; Protein Structure, Secondary; Protein Structure, Tertiary; Protozoan Proteins; rac GTP-Binding Proteins; rhoA GTP-Binding Protein; Sequence Alignment

2002
A rare combination of ribonucleotide reductases in the social amoeba Dictyostelium discoideum.
    The Journal of biological chemistry, 2013, Mar-22, Volume: 288, Issue:12

    Topics: Allosteric Regulation; Coordination Complexes; Cytidine Diphosphate; Dictyostelium; Enzyme Inhibitors; Free Radicals; Gene Expression; Gene Expression Regulation, Enzymologic; Guanosine Diphosphate; Iron; Kinetics; Phylogeny; Protozoan Proteins; Ribonucleotide Reductases; Spectrophotometry, Ultraviolet; Spores, Protozoan; Tyrosine

2013
KARATE: PKA-induced KRAS4B-RHOA-mTORC2 supercomplex phosphorylates AKT in insulin signaling and glucose homeostasis.
    Molecular cell, 2021, 11-18, Volume: 81, Issue:22

    Topics: 3T3-L1 Cells; Adipocytes; Animals; Cell Membrane; Cyclic AMP-Dependent Protein Kinases; Cytoskeleton; Dictyostelium; Glucose; Glucose Transporter Type 4; Guanosine Diphosphate; Guanosine Triphosphate; HEK293 Cells; Humans; Insulin; Mechanistic Target of Rapamycin Complex 2; Mice; Phosphorylation; Protein Transport; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins p21(ras); rhoA GTP-Binding Protein

2021