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1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and glycine

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with glycine in 21 studies

Compound Research Comparison

Studies
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Trials
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Recent Studies (post-2010)
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Studies
(glycine)
Trials
(glycine)
Recent Studies (post-2010) (glycine)
7,66601,65835,1637568,415

Protein Interaction Comparison

ProteinTaxonomy1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50)glycine (IC50)
Glutamate receptor ionotropic, NMDA 1 Rattus norvegicus (Norway rat)1.4852
Sodium- and chloride-dependent glycine transporter 1Homo sapiens (human)106
Glutamate receptor ionotropic, NMDA 2A Rattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2CRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 2DRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3BRattus norvegicus (Norway rat)0.3253
Glutamate receptor ionotropic, NMDA 3ARattus norvegicus (Norway rat)0.3253
Sodium- and chloride-dependent glycine transporter 2Homo sapiens (human)128

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19909 (42.86)18.7374
1990's7 (33.33)18.2507
2000's2 (9.52)29.6817
2010's3 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kakebeeke, PI; Konijn, TM; Mato, JM1
Crean, EV; Maldonado, B; Rossomando, EF1
Jahngen, EG; Kozwich, DL; Malliaros, DP1
Jahngen, EG; Rossomando, EF3
Kinsella, BA; Rossomando, EF; Thomas, HF; Whitehead, MC1
Jahngen, EG; Rossomando, EF; Soll, DR; Varnum, B1
Crean, EV; Lagerstedt, JP; Rossomando, EF1
Deville-Bonne, D; Glaser, P; Lascu, I; Véron, M1
Kubota, K; Oyama, M1
Patterson, B; Ruppel, KM; Spudich, JA; Wu, Y1
Devreotes, P; Long, Y; Xiao, Z; Yao, Y1
Batra, R; Geeves, MA; Manstein, DJ1
Ikebe, M; Ikebe, R; Kambara, T; Rhodes, TE; White, HD; Yamada, M1
Admiraal, SJ; Deville-Bonne, D; Herschlag, D; Janin, J; Meyer, P; Schneider, B1
Brenner, B; Furch, M; Manstein, DJ; Meyhöfer, E; Ruff, C1
KRICHEVSKY, MI; WRIGHT, BE1
Noguchi, TQ; Tokuraku, K; Toya, R; Ueno, H; Uyeda, TQ1
Cosson, P; Dias, M; Gopaldass, N; Le Coadic, M; Ouertatani-Sakouhi, H; Perrin, J; Vernay, A1
Ali, MS; Bozzaro, S; Bracco, E; Calautti, E; Cilloni, D; Levra Levron, C; Lo Iacono, M; Panuzzo, C; Pergolizzi, B; Ponzone, L; Prelli, M1

Other Studies

21 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and glycine

ArticleYear
Purification and preliminary characterization of an aggregation-sensitive chemoattractant of Dictyostelium minutum.
    Journal of bacteriology, 1978, Volume: 133, Issue:1

    Topics: Chemotaxis; Dictyostelium; Fungal Proteins; Glycine; Myxomycetes; Yeast, Dried

1978
Effect of hadacidin on growth and adenylosuccinate synthetase activity of Dictyostelium discoideum.
    Antimicrobial agents and chemotherapy, 1978, Volume: 14, Issue:3

    Topics: Adenylosuccinate Synthase; Cell Division; Dictyostelium; Formaldehyde; Glycine; Ligases

1978
Purification and characterization of developmentally regulated AMP deaminase from Dictyostelium discoideum.
    Differentiation; research in biological diversity, 1991, Volume: 46, Issue:3

    Topics: Adenosine Triphosphate; AMP Deaminase; Animals; Antibiotics, Antineoplastic; Chromatography; Cyclophosphamide; Dactinomycin; Dictyostelium; Dose-Response Relationship, Drug; Freeze Drying; Gene Expression Regulation, Enzymologic; Glycine; Guanosine Triphosphate; Molecular Weight; Phosphates; Sonication; Substrate Specificity

1991
AMP deaminase in Dictyostelium discoideum: increase in activity following nutrient deprivation induced by starvation or hadacidin.
    Molecular and cellular biochemistry, 1986, Volume: 71, Issue:1

    Topics: Adenosine Kinase; Adenosine Monophosphate; Adenosine Triphosphate; AMP Deaminase; Cell Division; Culture Media; Dictyostelium; Enzyme Activation; Formycins; Glycine; Guanosine Monophosphate; Hypoxanthine Phosphoribosyltransferase; Nucleotide Deaminases; Ribonucleotides; Substrate Specificity

1986
Effect of the amino acid analog hadacidin on intracellular membrane flow and the cell surface in Dictyostelium discoideum. A transmission- and scanning-electron-microscope study.
    Differentiation; research in biological diversity, 1986, Volume: 31, Issue:2

    Topics: Cell Membrane; Dictyostelium; Glycine; Membrane Fluidity; Microscopy, Electron; Microscopy, Electron, Scanning

1986
Adenylosuccinate synthetase from Dictyostelium discoideum: effects of hadacidin analogs and binding of [14C]hadacidin.
    Archives of biochemistry and biophysics, 1984, Feb-15, Volume: 229, Issue:1

    Topics: Adenylosuccinate Synthase; Aspartic Acid; Chromatography; Dictyostelium; Glycine; Ligases; Substrate Specificity

1984
Permeability of Dictyostelium discoideum to fucose and uracil following growth-arrest induced by starvation, hadacidin, and cerulenin.
    Differentiation; research in biological diversity, 1982, Volume: 23, Issue:1

    Topics: Antifungal Agents; Biological Transport, Active; Cell Division; Cell Membrane Permeability; Cerulenin; Dictyostelium; Fucose; Glycine; Pinocytosis; Starvation; Uracil

1982
Inhibition of a nutrient-dependent pinocytosis in Dictyostelium discoideum by the amino acid analogue hadacidin.
    The Journal of cell biology, 1981, Volume: 91, Issue:1

    Topics: Antibiotics, Antineoplastic; Cell Division; Culture Media; Dictyostelium; Formaldehyde; Glucose; Glycine; Morphogenesis; Pinocytosis

1981
Lysosomal abnormalities in hadacidin-treated Dictyostelium discoideum amoebae.
    Journal of general microbiology, 1981, Volume: 123, Issue:2

    Topics: Dictyostelium; Formaldehyde; Glycine; Lysosomes; Sucrose

1981
Equilibrium dissociation and unfolding of nucleoside diphosphate kinase from Dictyostelium discoideum. Role of proline 100 in the stability of the hexameric enzyme.
    The Journal of biological chemistry, 1993, Sep-25, Volume: 268, Issue:27

    Topics: Amino Acid Sequence; Animals; Base Sequence; Chromatography, Gel; Circular Dichroism; Dictyostelium; Enzyme Stability; Glycine; Kinetics; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Nucleoside-Diphosphate Kinase; Oligodeoxyribonucleotides; Proline; Protein Conformation; Protein Denaturation; Protein Folding; Protein Structure, Secondary; Recombinant Proteins; Serine; Spectrophotometry, Ultraviolet; Urea

1993
H+ secretion induced by hypertonic stress in the cellular slime mold Dictyostelium discoideum.
    Journal of biochemistry, 1997, Volume: 122, Issue:1

    Topics: Adaptation, Physiological; Amiloride; Animals; Cell Size; Culture Media; Dictyostelium; Glycine; Hydrogen-Ion Concentration; Hypertonic Solutions; Mannitol; Potassium Chloride; Protons; Sodium Chloride; Stress, Physiological

1997
Cold-sensitive mutants G680V and G691C of Dictyostelium myosin II confer dramatically different biochemical defects.
    The Journal of biological chemistry, 1997, Oct-31, Volume: 272, Issue:44

    Topics: Actins; Amino Acid Sequence; Animals; Calcium-Transporting ATPases; Cold Temperature; Dictyostelium; Glycine; Molecular Sequence Data; Mutagenesis, Site-Directed; Mutation; Myosins; Protein Binding

1997
Desensitization of G-protein-coupled receptors. agonist-induced phosphorylation of the chemoattractant receptor cAR1 lowers its intrinsic affinity for cAMP.
    The Journal of biological chemistry, 1999, Jan-15, Volume: 274, Issue:3

    Topics: Alanine; Amino Acid Substitution; Animals; Cell Line; Cholic Acids; Chromatography, Affinity; Cyclic AMP; Detergents; Dictyostelium; Glycine; GTP-Binding Proteins; Kinetics; Ligands; Nickel; Phosphorylation; Receptors, Cyclic AMP

1999
Kinetic analysis of Dictyostelium discoideum myosin motor domains with glycine-to-alanine mutations in the reactive thiol region.
    Biochemistry, 1999, May-11, Volume: 38, Issue:19

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Alanine; Animals; Dictyostelium; Glycine; Kinetics; Mutation; Myosins; Sulfhydryl Compounds

1999
Functional significance of the conserved residues in the flexible hinge region of the myosin motor domain.
    The Journal of biological chemistry, 1999, Jun-04, Volume: 274, Issue:23

    Topics: Actins; Adenosine Triphosphate; Animals; Ca(2+) Mg(2+)-ATPase; Crystallography, X-Ray; Dictyostelium; Escherichia coli; Glycine; Hydrolysis; Isoleucine; Models, Molecular; Muscle, Smooth; Myosins; Photoaffinity Labels; Protein Conformation; Spectrometry, Fluorescence; Spodoptera; Structure-Activity Relationship; Xenopus

1999
Chemical rescue of phosphoryl transfer in a cavity mutant: a cautionary tale for site-directed mutagenesis.
    Biochemistry, 2001, Jan-16, Volume: 40, Issue:2

    Topics: Adenosine Triphosphate; Alanine; Alcohols; Amines; Animals; Chromatography, High Pressure Liquid; Crystallography, X-Ray; Dictyostelium; Enzyme Activation; Glycine; Histidine; Hydrogen-Ion Concentration; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Nucleoside-Diphosphate Kinase; Phosphorylation; Solutions; Solvents; Thermodynamics

2001
Single-molecule tracking of myosins with genetically engineered amplifier domains.
    Nature structural biology, 2001, Volume: 8, Issue:3

    Topics: Animals; Dictyostelium; Glycine; Lasers; Molecular Motor Proteins; Myosins; Protein Engineering; Protein Structure, Tertiary; Rabbits; Recombinant Fusion Proteins; Rotation

2001
ENVIRONMENTAL CONTROL OF THE COURSE OF DEVELOPMENT IN DICTYOSTELIUM DISCOIDEUM.
    Journal of general microbiology, 1963, Volume: 32

    Topics: Alanine; Calcium; Calcium, Dietary; Carbohydrate Metabolism; Chlorides; Citrates; Culture Media; Cysteine; Dictyostelium; Fungi; Glucose; Glycine; Histidine; Hydrogen-Ion Concentration; Magnesium; Potassium; Proteins; Sodium; Succinates

1963
Screening of novel dominant negative mutant actins using glycine targeted scanning identifies G146V actin that cooperatively inhibits cofilin binding.
    Biochemical and biophysical research communications, 2010, Jun-11, Volume: 396, Issue:4

    Topics: Actin Cytoskeleton; Actin Depolymerizing Factors; Actins; Amino Acid Sequence; Dictyostelium; DNA Mutational Analysis; Glycine; Molecular Sequence Data; Mutation; Protein Binding; Protein Conformation; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins

2010
TM9 family proteins control surface targeting of glycine-rich transmembrane domains.
    Journal of cell science, 2015, Jul-01, Volume: 128, Issue:13

    Topics: Animals; Cell Membrane; Dictyostelium; Endoplasmic Reticulum; Glycine; HEK293 Cells; Humans; Models, Biological; Protein Binding; Protein Structure, Tertiary; Protein Transport; Protozoan Proteins

2015
Two conserved glycine residues in mammalian and
    Journal of cell science, 2019, 11-14, Volume: 132, Issue:22

    Topics: Amino Acid Sequence; Animals; Dictyostelium; Glycine; Humans; Mammals; Mechanistic Target of Rapamycin Complex 2; Rapamycin-Insensitive Companion of mTOR Protein; Structure-Activity Relationship

2019