Page last updated: 2024-09-03

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and fluorouracil

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with fluorouracil in 3 studies

Compound Research Comparison

Studies
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Trials
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Recent Studies (post-2010)
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Studies
(fluorouracil)
Trials
(fluorouracil)
Recent Studies (post-2010) (fluorouracil)
7,66601,65845,5629,30714,663

Protein Interaction Comparison

ProteinTaxonomy1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50)fluorouracil (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.32
Thymidylate synthaseMus musculus (house mouse)1.58
AromataseHomo sapiens (human)0.63

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Berta, GN; Ceccarelli, A; Ceppi, P; Di Carlo, F; Di Scipio, F; Papotti, M; Salamone, P; Scagliotti, GV; Sprio, AE1
Alexander, H; Alexander, S; Min, J; Stegner, AL1
Alexander, H; Alexander, S; Hanigan, MH; Min, J; Stegner, AL; Traynor, D; Zhang, L1

Other Studies

3 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and fluorouracil

ArticleYear
Differentiation-inducing factor-1 enhances 5-fluorouracil action on oral cancer cells inhibiting E2F1 and thymidylate synthase mRNAs accumulation.
    Cancer chemotherapy and pharmacology, 2012, Volume: 69, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cell Growth Processes; Cell Line, Tumor; Cell Survival; Drug Synergism; E2F1 Transcription Factor; Fluorouracil; Gene Expression; Hexanones; Humans; Mouth Neoplasms; RNA, Messenger; Signal Transduction; Thymidylate Synthase

2012
Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs.
    Eukaryotic cell, 2004, Volume: 3, Issue:3

    Topics: Aldehyde-Lyases; Animals; Carboplatin; Cell Death; Cell Enlargement; Cell Nucleus; Ceramides; Cisplatin; Cloning, Molecular; Dictyostelium; Doxorubicin; Enzyme Inhibitors; Fluorouracil; Mutation; Parasitic Sensitivity Tests; Phosphotransferases (Alcohol Group Acceptor); Sphingolipids; Sphingosine

2004
Sphingosine kinase regulates the sensitivity of Dictyostelium discoideum cells to the anticancer drug cisplatin.
    Eukaryotic cell, 2005, Volume: 4, Issue:1

    Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antineoplastic Agents; Blotting, Western; Cisplatin; Dictyostelium; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance; Etoposide; Fluorouracil; Microscopy, Fluorescence; Models, Genetic; Molecular Sequence Data; Mutation; Phosphotransferases (Alcohol Group Acceptor); Recombination, Genetic; Sensitivity and Specificity; Sequence Homology, Amino Acid; Sphingosine; Time Factors

2005