1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and cyclic gmp

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with cyclic gmp in 172 studies

Compound Research Comparison

Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Studies (cyclic gmp)	Trials (cyclic gmp)	Recent Studies (post-2010) (cyclic gmp)
7,666	0	1,658	22,346	333	4,062

Protein Interaction Comparison

Protein	Taxonomy	cyclic gmp (IC50)
Phosphodiesterase	Bos taurus (cattle)	0.1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	Homo sapiens (human)	2.4
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	Homo sapiens (human)	2.4

Research

Studies (172)

Timeframe	Studies, this research(%)	All Research%
pre-1990	71 (41.28)	18.7374
1990's	48 (27.91)	18.2507
2000's	40 (23.26)	29.6817
2010's	11 (6.40)	24.3611
2020's	2 (1.16)	2.80

Authors

Authors	Studies
Kay, RR; Wurster, B	1
Chen, ZH; Du, Q; Kawabe, Y; Schaap, P; Schilde, C	1
Gerisch, G; Hülser, D; Malchow, D; Wick, U	1
Brenner, M; Ward, A	1
Eckstein, F; Gerisch, G; Malchow, D; Nanjundiah, V; Wurster, B	1
Malchow, D; Mato, JM	1
Chia, WK	1
Henderson, EJ	1
Pedersen, LG; Putnam, JB	1
Green, AA; Newell, PC	1
Brachet, P; Da Silva, LH; Darmon, M	1
Beattie, DS; Kobilinsky, L; Weinstein, BI	1
Eckert, BS; Rubin, RW; Warren, RH	1
George, RP	1
Gerisch, G; Schubiger, K; Wick, U; Wurster, B	1
Konijn, TM; Krens, FA; Mato, JM; van Haastert, PJ	3
Dobbe, FC; Konijn, TM; Krens, FA; Mato, JM; Rhijnsburger, EH; Van Haastert, PJ	1
Gross, J; Town, C	1
Gerisch, G; Malchow, D; Rahmsdorf, HJ	1
Konijn, TM; Mato, JM; van Haastert, PJ; Woelders, H	1
Gerisch, G; Rahmsdorf, HJ	1
Gross, J; Sampson, J; Town, C	1
Konijn, TM; Mato, JM; Woelders, H	1
Pai, SH; Rahmsdorf, HJ	1
Brachet, P; Schubiger, K; Wurster, B	1
Pan, P; Wedner, HJ	1
Butler, JR; Coukell, MB	1
Segall, JE	1
Liu, G; Newell, PC	5
Arents, JC; Schoen, CD; Schulkes, CC; Van Driel, R	2
Valkema, R; Van Haastert, PJ	2
Peters, DJ; Schaap, P; Snaar-Jagalska, BE; Van Haastert, PJ	1
Howlett, A; Klein, C; Tao, Y	1
Bumann, J; Jaworski, E; Malchow, D; Menz, S	1
Firtel, RA; Hadwiger, JA; Kumagai, A; Pupillo, M	1
Oyama, M	2
Fontana, DR; Luo, CS; Phillips, JC	1
Snaar-Jagalska, BE; Van Haastert, PJ	2
Van der Molen, LG; Van Duijn, B; Van Haastert, PJ; Vogelzang, SA; Ypey, DL	1
Wanner, R; Wurster, B	1
Coukell, MB; Parissenti, AM	1
Van Duijn, B; Wang, M	1
Orii, H; Tanaka, Y; Yanagisawa, K	1
De Jong, CC; Janssens, PM; Van Haastert, PJ; Vink, AA	1
Mohn, R; Wurster, B	1
De Lozanne, A; Knecht, DA; Loomis, WF; Peters, DJ; Spudich, J; Van Haastert, PJ	1
Cameron, AM; Coukell, MB	1
Europe-Finner, GN; Newell, PC; Small, NV	2
Bonner, JT; Calandra, TD; De Wit, RJ; Penning, LC; Pinas, JE; van Bemmelen, MX	1
Kesbeke, F; Van Haastert, PJ	1
van Haastert, PJ	6
Pinas, J; Schaap, P; Spek, W; Van Driel, R; Van Haastert, PJ; Van Lookeren Campagne, MM	1
Bulgakov, R; De Wit, RJ; Konijn, TM; Rinke de Wit, TF	1
Firtel, RA; Kesbeke, F; Luderus, E; Reymond, CD; Van Driel, R; Van Haastert, PJ	1
Bominaar, TA; Bulgakov, R; de Wit, RJ; Rinke de Wit, TF	1
de Jong, CC; Janssens, PM	1
Schaap, P; Wang, M	1
Europe-Finner, GN; Newell, PC	2
Baraniak, J; Bulgakov, R; Jastorff, B; Kesbeke, F; Morr, M; Petridis, G; Seela, F; Stec, WJ; Van Haastert, PJ	1
Devreotes, P; Jastorff, B; Palmisano, M; Theibert, A	1
Europe Finner, GN; McRobbie, SJ; Newell, PC; Tillinghast, HS	1
Tasaka, M; Tsang, AS	1
Mato, JM; Steiner, AL	1
Brown, SS; Rutherford, CL	1
Alemany, S; García Gil, M; Mato, JM	1
Grutsch, JF; Robertson, AD	1
Bumann, J; Wurster, B	1
Bulgakov, R; Konijn, TM; van der Meer, RC; van Haastert, PJ; van Walsum, H	1
Newell, PC; Ross, FM	1
Kaleko, M; Rothman, FG	1
Pasveer, FJ; Van Haastert, PJ; Van Walsum, H	1
Brachet, P; De Gunzburg, J	1
Brachet, P; Dicou, E	1
Konijn, TM; Pasveer, FJ; van der Heijden, PR; van der Meer, RC; van Haastert, PJ; van Walsum, H	1
Coukell, MB; Lappano, S	1
Ross, FM; van Haastert, PJ; van Lookeren Campagne, MM	1
Van der Heijden, PR; Van Haastert, PJ	1
Butz, U; Wurster, B	1
Kien, E; Van Haastert, PJ	1
Brenner, M; Thoms, SD	1
Van Haastert, PJ; Van Lookeren Campagne, MM	1
Ishida, S; Kuwayama, H; Van Haastert, PJ; Viel, GT	1
Clark, AM; Cubitt, AB; Dharmawardhane, S; Firtel, RA	1
Ishida, S; Kuwayama, H; Van Haastert, PJ	1
Howlett, AC; Klein, C; Tao, Y	1
Firtel, RA; Hadwiger, JA; Lee, S	1
Devreotes, PN; Insall, RH; Schaap, P; Soede, RD	1
Yumura, S	1
Darcy, PK; Fisher, PR; Wilczynska, Z	1
Brandt, R; Devreotes, PN; Lin, KC; Pitt, GS; Schaap, P	1
Ishida, S; Kuwayama, H; Liu, G; Newell, PC	1
Bozzaro, S; Bussolino, F; Cristino, E; Sordano, C; Wurster, B	1
Gross, JD; Malchow, D; Newell, PC	1
Ecke, M; Gerisch, G; Kuwayama, H; Van Haastert, PJ	1
Dembinsky, A; Ravid, S; Rubin, H	1
Kuwayama, H; Van Haastert, PJ	4
Insall, RH	1
Newell, PC	1
Chen, MY; Devreotes, PN; Long, Y	1
Silveira, LA; Smith, JL; Spudich, JA; Tan, JL	1
Firtel, RA; Gamper, M; Howard, PK; Hunter, T; Kim, E; Ma, H	1
Derks, M; Kuwayama, H; Roelofs, J; Snippe, H; Van Haastert, PJ	1
Kleineidam, RG; Roelofs, J; Snippe, H; Van Haastert, PJ	1
Ammann, R; Gao, T; Gomer, RH; Tang, L	1
Epskamp, SJ; Harten, V; Knetsch, ML; Lagendijk, EL; Schenk, PW; Snaar-Jagalska, BE; van Duijn, B	1
Bosgraaf, L; Goldberg, JM; Smith, JL; Van Haastert, PJ	1
Chiem, B; Gomer, RH; Jang, W	1
Ip, H; Kae, H; Kang, R; Spiegelman, GB; Weeks, G	1
Bosgraaf, L; Russcher, H; Smith, JL; Soll, DR; Van Haastert, PJ; Wessels, D	1
Levine, H; Loomis, WF; Rappel, WJ; Thomas, PJ	1
Biondi, RM; Meima, ME; Schaap, P	1
Bader, S; Bosgraaf, L; Russcher, H; Snippe, H; Van Haastert, PJ; Wind, J	1
Roelofs, J; Smith, JL; Van Haastert, PJ	1
Abe, T; Araki, T; Fukuzawa, M; Katoh, M; Maeda, M; Meima, M; Morio, T; Schaap, P; Takeuchi, I; Tanaka, Y; Tsujioka, M; Urushihara, H; Williams, JG	1
Kimmel, AR; Parent, CA	1
Bosgraaf, L; Van Haastert, PJ	4
Ammann, R; Brock, DA; Ehrenman, K; Gomer, RH; Tang, Y	1
De Boer, JS; Van Haastert, PJ; Veltman, DM	1
Bosgraaf, L; Loovers, HM; Postma, M; Van Haastert, PJ	1
Brzostowski, JA; Kimmel, AR; Parent, CA	1
Bosgraaf, L; Van Haastert, PJ; Veltman, DM	1
Lusche, DF; Malchow, D	1
Engel, R; Roelofs, J; Van Haastert, PJ; Veltman, DM; Visser, AJ	1
Bosgraaf, L; Engel, R; Soll, D; van Haastert, PJ; Visser, AJ; Waijer, A; Wessels, D	1
Kaneko, H; Lusche, DF; Malchow, D	1
Bosgraaf, L; Clarkson, BK; Goldberg, JM; Smith, JL; Van Haastert, PJ; Wolpin, ES	1
Van Haastert, PJ; Veltman, DM	3
Bolourani, P; Spiegelman, GB; Weeks, G	1
Bader, S; Kortholt, A; Van Haastert, PJ	1
Bumann, J; Malchow, D; Wurster, B	1
Hadwiger, JA	1
Blaesius, D; Lusche, DF; Schaloske, RH; Schlatterer, C	1
Gomer, RH; Jang, W	1
Bosgraaf, L; Bosgraaf, S; Keizer-Gunnink, I; Kortholt, A; Plak, K; van Egmond, WN; van Haastert, PJ	1
Kuwayama, H; Sato, MJ; Takagi, H; Takayama, AL; Ueda, M; van Egmond, WN; van Haastert, PJ; Yanagida, T	1
Kubohara, Y; Kuwayama, H	1
Araki, T; van Egmond, WN; van Haastert, PJ; Williams, JG	1
Bosgraaf, L; Keizer-Gunnink, I; Kortholt, A; Plak, K; van Egmond, WN; van Haastert, PJ	1
Chen, ZH; Schaap, P	2
Anielski, A; Beta, C; Gerhardt, M; Pfannes, EK	1
Schaap, P	1
Giusti, C; Golstein, P; Luciani, MF; Song, Y	1
Barton, GJ; Chen, ZH; Cole, C; Febrer, M; Lawal, HM; Schaap, P; Schilde, C; Singh, R	1
Jahan, MGS; Kondo, T; Nakano, M; Tanaka, Y; Yumura, S	1
Keizer-Gunnink, I; Kortholt, A; Ortiz-Mateos, C; Pots, H; van Egmond, W; van Haastert, PJM; Veltman, D	1
Hashimoto, Y; Honda, A; Kondo, T; Nakano, M; Yumura, S	1

Reviews

18 review(s) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and cyclic gmp

Article	Year
The Evolution of Aggregative Multicellularity and Cell-Cell Communication in the Dictyostelia. Journal of molecular biology, 2015, Nov-20, Volume: 427, Issue:23 Topics: Biological Evolution; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dictyostelium; Genome, Protozoan; Genomics; Hexanones; Histidine Kinase; Protein Kinases; Protozoan Proteins; Quorum Sensing; Signal Transduction	2015
Streamer F mutants and chemotaxis of Dictyostelium. BioEssays : news and reviews in molecular, cellular and developmental biology, 1992, Volume: 14, Issue:7 Topics: Animals; Calcium; Calcium-Calmodulin-Dependent Protein Kinases; Chemotaxis; Cyclic AMP; Cyclic GMP; Cytoskeleton; Dictyostelium; Fungal Proteins; Mutation; Myosins; Phenotype; Phosphorylation; Phosphotransferases; Protozoan Proteins; Signal Transduction	1992
Signal transduction during amoebal chemotaxis of Dictyostelium discoideum. Microbiological sciences, 1987, Volume: 4, Issue:1 Topics: Actins; Chemotaxis; Cyclic GMP; Dictyostelium; Receptors, Cyclic AMP; Signal Transduction	1987
Aggregation in Dictyostelium discoideum. Cell, 1981, Volume: 24, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid; Interphase; Kinetics; Movement; Receptors, Cyclic AMP	1981
Transduction of the chemotactic cAMP signal across the plasma membrane of Dictyostelium cells. Experientia, 1995, Dec-18, Volume: 51, Issue:12 Topics: Adenylyl Cyclases; Animals; Calcium; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; GTP-Binding Proteins; Inositol Phosphates; Receptors, Cyclic AMP; Signal Transduction; Type C Phospholipases	1995
The role of calcium in aggregation and development of Dictyostelium. Experientia, 1995, Dec-18, Volume: 51, Issue:12 Topics: Animals; Calcium; Calcium-Transporting ATPases; Chemotaxis; Cyclic GMP; Cytoskeleton; Dictyostelium	1995
Cyclic GMP and the big squeeze. Osmoregulation. Current biology : CB, 1996, May-01, Volume: 6, Issue:5 Topics: Animals; Cyclic GMP; Dictyostelium; Osmosis; Osmotic Pressure	1996
Signal transduction and motility of Dictyostelium. Bioscience reports, 1995, Volume: 15, Issue:6 Topics: Actins; Animals; Calcium; Chemotaxis; Cyclic AMP; Cyclic GMP; Cytoskeleton; Dictyostelium; Ion Transport; Myosin-Light-Chain Kinase; Myosins; Signal Transduction	1995
cGMP as second messenger during Dictyostelium chemotaxis. FEBS letters, 1997, Jun-23, Volume: 410, Issue:1 Topics: Animals; Chemotaxis; Cyclic GMP; Dictyostelium; GTP-Binding Proteins; Guanylate Cyclase; Receptors, Formyl Peptide; Receptors, Immunologic; Receptors, Peptide; Second Messenger Systems; Water-Electrolyte Balance	1997
A model for cGMP signal transduction in Dictyostelium in perspective of 25 years of cGMP research. Journal of muscle research and cell motility, 2002, Volume: 23, Issue:7-8 Topics: Animals; Cloning, Molecular; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Kinetics; Models, Biological; Myosins; Phosphoric Diester Hydrolases; Phosphorylation; Signal Transduction	2002
Chemotaxis: signalling modules join hands at front and tail. EMBO reports, 2004, Volume: 5, Issue:1 Topics: Animals; Cell Shape; Chemotaxis; Cyclic GMP; Dictyostelium; Phosphatidylinositol Phosphates; Pseudopodia; Signal Transduction	2004
Unusual Guanylyl Cyclases and cGMP Signaling in Dictyostelium discoideum. Vitamins and hormones, 2004, Volume: 69 Topics: Animals; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Signal Transduction	2004
The regulation of myosin II in Dictyostelium. European journal of cell biology, 2006, Volume: 85, Issue:9-10 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Actin Cytoskeleton; Animals; Calcium-Calmodulin-Dependent Protein Kinases; Cell Movement; Cyclic AMP-Dependent Protein Kinase Type II; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Cytoskeleton; Diacylglycerol Kinase; Dictyostelium; Myosin Heavy Chains; Myosin Type II; Protozoan Proteins; Signal Transduction	2006
Chemotaxis: navigating by multiple signaling pathways. Science's STKE : signal transduction knowledge environment, 2007, Jul-24, Volume: 2007, Issue:396 Topics: Animals; Chemotactic Factors; Chemotaxis; Chromones; Cyclic AMP; Cyclic GMP; Cytoskeleton; Dictyostelium; Dose-Response Relationship, Drug; Guanylate Cyclase; Models, Biological; Morpholines; Osmolar Concentration; Phosphatidylinositol 3-Kinases; Phosphatidylinositol 4,5-Diphosphate; Phosphatidylinositol Phosphates; Phosphoinositide-3 Kinase Inhibitors; Phospholipases A; Phosphorylation; Protozoan Proteins; Pseudopodia; PTEN Phosphohydrolase; Second Messenger Systems; Stochastic Processes	2007
Combining experiments and modelling to understand size regulation in Dictyostelium discoideum. Journal of the Royal Society, Interface, 2008, Aug-06, Volume: 5 Suppl 1 Topics: Animals; Cell Adhesion; Computer Simulation; Cyclic AMP; Cyclic GMP; Dictyostelium; Models, Biological; Movement; Protozoan Proteins; Signal Transduction	2008
Cyclic di-nucleotide signaling enters the eukaryote domain. IUBMB life, 2013, Volume: 65, Issue:11 Topics: Bacterial Proteins; Biofilms; Cyclic GMP; Dictyostelium; Dinucleoside Phosphates; Humans; Immunity, Innate; Membrane Proteins; Nucleotides, Cyclic; Nucleotidyltransferases; Phylogeny; Protein Structure, Tertiary; Second Messenger Systems; Signal Transduction	2013
Secreted Cyclic Di-GMP Induces Stalk Cell Differentiation in the Eukaryote Dictyostelium discoideum. Journal of bacteriology, 2016, 01-01, Volume: 198, Issue:1 Topics: Cyclic GMP; Dictyostelium; Signal Transduction; Spores, Protozoan	2016
Forty-five years of cGMP research in Molecular biology of the cell, 2021, 10-01, Volume: 32, Issue:20 Topics: Actins; Cell Membrane; Cell Movement; Cell Polarity; Chemotactic Factors; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Protein Transport; Pseudopodia; Signal Transduction	2021

Other Studies

154 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and cyclic gmp

Article	Year
New roles for DIF? Effects on early development in Dictyostelium. Developmental biology, 1990, Volume: 140, Issue:1 Topics: Cell Adhesion; Cell Aggregation; Cyclic AMP; Cyclic GMP; Dictyostelium; Dose-Response Relationship, Drug; Hexanones; Ketones; Pentanones	1990
Cell communication by periodic cyclic-AMP pulses. Philosophical transactions of the Royal Society of London. Series B, Biological sciences, 1975, Nov-06, Volume: 272, Issue:915 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Binding Sites; Cell Aggregation; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Models, Biological; Myxomycetes; Receptors, Drug	1975
Guanylate cyclase from Dictyostelium discoideum. Life sciences, 1977, Oct-01, Volume: 21, Issue:7 Topics: Animals; Cyclic GMP; Dictyostelium; Guanosine Triphosphate; Guanylate Cyclase; Hydrogen-Ion Concentration; Kinetics; Magnesium; Manganese; Myxomycetes; Phosphoric Diester Hydrolases; Phosphorus Radioisotopes; Proteins; Temperature	1977
Cyclic AMP-induced pH changes in Dictyostelium discoideum and their control by calcium. Biochimica et biophysica acta, 1978, Feb-01, Volume: 538, Issue:3 Topics: Calcium; Cyclic AMP; Cyclic GMP; Dictyostelium; Dithiothreitol; Extracellular Space; Glutaral; Hydrogen-Ion Concentration; Myxomycetes; Receptors, Cyclic AMP	1978
Guanylate cyclase activation in response to chemotactic stimulation in Dictyostelium discoideum. FEBS letters, 1978, Jun-01, Volume: 90, Issue:1 Topics: Adenosine Triphosphate; Cell Aggregation; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Guanylate Cyclase; Hydrogen-Ion Concentration; Myxomycetes	1978
Induction of stalk cell differentiation by cyclic-AMP in a susceptible variant of Dictyostelium discoideum. Developmental biology, 1975, Volume: 44, Issue:2 Topics: Adenosine; Adenosine Monophosphate; Amoeba; Cell Aggregation; Cell Differentiation; Cells, Cultured; Chemotaxis; Clone Cells; Cyclic AMP; Cyclic GMP; Dialysis; Dictyostelium; Escherichia coli; Genetic Variation; Growth; Myxomycetes; Phosphoric Diester Hydrolases; Spores, Fungal	1975
The cyclic adenosine 3':5'-monophosphate receptor of Dictyostelium discoideum. Binding characteristics of aggregation-competent cells and variation of binding levels during the life cycle. The Journal of biological chemistry, 1975, Jun-25, Volume: 250, Issue:12 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adrenal Cortex; Animals; Binding Sites; Binding, Competitive; Cattle; Cell Division; Cyclic AMP; Cyclic GMP; Dictyostelium; Dithiothreitol; Fungal Proteins; Myxomycetes; Protein Binding; Receptors, Drug; Time Factors	1975
Discovery of a 3',5'-guanosine monophosphate simulating factor in amoebae of Dictyostelium discoideum. Biochimica et biophysica acta, 1975, Nov-10, Volume: 411, Issue:1 Topics: Animals; Cyclic GMP; Dictyostelium; Isotope Labeling; Myxomycetes; Tritium	1975
Evidence for the existence of two types of cAMP binding sites in aggregating cells of Dictyostelium discoideum. Cell, 1975, Volume: 6, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Binding Sites; Binding, Competitive; Cell Membrane; Chemotaxis; Cyclic AMP; Cyclic GMP; Depression, Chemical; Dictyostelium; Dithiothreitol; Kinetics; Myxomycetes; Structure-Activity Relationship; Subcellular Fractions	1975
Chemotactic signals induce cell differentiation in Dictyostelium discoideum. Proceedings of the National Academy of Sciences of the United States of America, 1975, Volume: 72, Issue:8 Topics: Adenosine Monophosphate; Cell Aggregation; Cell Differentiation; Chemotaxis; Contact Inhibition; Cyclic AMP; Cyclic GMP; Dictyostelium; Edetic Acid; Mutation; Myxomycetes	1975
The induction of filopodia in the cellular slime mold Dictyostelium discoideum by cyclic adenosine monophosphate: mechanism of aggregation. Developmental biology, 1976, Volume: 48, Issue:2 Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Azides; Cell Aggregation; Concanavalin A; Cyclic AMP; Cyclic GMP; Dictyostelium; Dinitrophenols; Myxomycetes; Pseudopodia	1976
Structural and biochemical aspects of cell motility in amebas of Dictyostelium discoideum. The Journal of cell biology, 1977, Volume: 72, Issue:2 Topics: Actins; Colchicine; Cyclic AMP; Cyclic GMP; Cytoplasm; Cytoskeleton; Dictyostelium; Griseofulvin; Microtubules; Movement; Myxomycetes; Pseudopodia	1977
Disruption of multicellular organization in the cellular slime molds by cyclic AMP. Cell differentiation, 1977, Volume: 5, Issue:5-6 Topics: Adenine Nucleotides; Bucladesine; Cell Differentiation; Cyclic AMP; Cyclic GMP; Dictyostelium; Guanine Nucleotides; Myxomycetes; Species Specificity; Spores, Fungal	1977
Cyclic GMP in Dictyostelium discoideum, Oscillations and pulses in response to folic acid and cyclic AMP signals. FEBS letters, 1977, Apr-15, Volume: 76, Issue:2 Topics: Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid; Kinetics; Myxomycetes	1977
3':5'-cyclic AMP-dependent 3':5'-cyclic GMP accumulation in Dictyostelium discoideum. Proceedings of the National Academy of Sciences of the United States of America, 1977, Volume: 74, Issue:6 Topics: Adenosine Monophosphate; Cyclic AMP; Cyclic GMP; Cyclic IMP; Dictyostelium; Dose-Response Relationship, Drug; Kinetics; Myxomycetes; Structure-Activity Relationship	1977
Unified control of chemotaxis and cAMP mediated cGMP accumulation by cAMP in Dictyostelium discoideum. Biochemical and biophysical research communications, 1977, Jul-11, Volume: 77, Issue:1 Topics: Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Kinetics; Myxomycetes; Receptors, Cyclic AMP	1977
Cyclic AMP and folic acid mediated cyclic GMP accumulation in Dictyostelium discoideum. FEBS letters, 1977, Jul-15, Volume: 79, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Dithiothreitol; Dose-Response Relationship, Drug; Folic Acid; Kinetics; Myxomycetes; Structure-Activity Relationship	1977
The role of cyclic nucleotides and cell agglomeration in postaggregative enzyme synthesis in Dictyostelium discoideum. Developmental biology, 1978, Volume: 63, Issue:2 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Induction; Kinetics; Myxomycetes; Phosphorylases; Transferases; UTP-Glucose-1-Phosphate Uridylyltransferase	1978
Cyclic AMP-induced phosphorylation in Dictyostelium of a polypeptide comigrating with myosin heavy chains. FEBS letters, 1978, Apr-15, Volume: 88, Issue:2 Topics: Calcium; Cyclic AMP; Cyclic GMP; Dictyostelium; Fungal Proteins; Molecular Weight; Myosins; Myxomycetes; Phosphates; Receptors, Cyclic AMP	1978
Chemotaxis in Dictyostelium discoideum: effect of concanavalin A on chemoattractant mediated cyclic gmp accumulation anlight scattering decrease. Cell biology international reports, 1978, Volume: 2, Issue:2 Topics: Chemotaxis; Concanavalin A; Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid; Light; Myxomycetes; Scattering, Radiation	1978
Cyclic GMP binding activity in Dictyostelium discoideum. FEBS letters, 1978, Jun-15, Volume: 90, Issue:2 Topics: Cell Differentiation; Cyclic GMP; Cytosol; Dictyostelium; Kinetics; Myxomycetes; Receptors, Drug	1978
Specific binding proteins for cyclic AMP and cyclic GMP in Dictyostelium discoideum. Cell differentiation, 1978, Volume: 7, Issue:5 Topics: Cell Cycle; Chromatography, DEAE-Cellulose; Chromatography, Gel; Cyclic AMP; Cyclic GMP; Dictyostelium; Protein Kinases; Receptors, Cyclic AMP	1978
Cyclic AMP and the control of aggregative phase gene expression in Dictyostelium discoideum. Developmental biology, 1978, Volume: 67, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cyclic AMP; Cyclic GMP; Dictyostelium; Kinetics; Phosphorylases	1978
Intracellular cyclic GMP-binding proteins in cellular slime molds. Journal of bacteriology, 1979, Volume: 137, Issue:1 Topics: Carrier Proteins; Cyclic GMP; Dictyostelium; Fungal Proteins; Myxomycetes; Protein Kinases	1979
Protein kinases of Dictyostelium discoideum, strain AX-2. Biochimica et biophysica acta, 1979, Apr-12, Volume: 567, Issue:2 Topics: Caseins; Cyclic AMP; Cyclic GMP; Dictyostelium; Histones; Molecular Weight; Protein Kinases; Substrate Specificity	1979
Cyclic GMP and cyclic AMP changes in response to folic acid pulses during cell development of Dictyostelium discoideum. Cell differentiation, 1979, Volume: 8, Issue:3 Topics: Cell Adhesion; Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid	1979
Immunohistochemical localization of cyclic GMP in aggregating Polysphondylium violaceum. Differentiation; research in biological diversity, 1979, Volume: 14, Issue:1-2 Topics: Cell Aggregation; Cyclic GMP; Dictyostelium; Fluorescent Antibody Technique	1979
Association of a cGMP-binding activity with nuclei isolated from amoebae of Dictyostelium discoideum and Polysphondylium violaceum. Biochemistry and cell biology = Biochimie et biologie cellulaire, 1992, Volume: 70, Issue:2 Topics: Animals; Cell Fractionation; Cell Nucleus; Cyclic GMP; Dictyosteliida; Dictyostelium; Kinetics	1992
Behavioral responses of streamer F mutants of Dictyostelium discoideum: effects of cyclic GMP on cell motility. Journal of cell science, 1992, Volume: 101 ( Pt 3) Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cell Aggregation; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Kinetics; Mutation	1992
A soluble factor and GTP gamma S are required for Dictyostelium discoideum guanylate cyclase activity. Biochimica et biophysica acta, 1992, Apr-30, Volume: 1135, Issue:1 Topics: Animals; Cyclic GMP; Cytosol; Dictyostelium; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanylate Cyclase; Signal Transduction	1992
Inhibition of receptor-stimulated guanylyl cyclase by intracellular calcium ions in Dictyostelium cells. Biochemical and biophysical research communications, 1992, Jul-15, Volume: 186, Issue:1 Topics: Animals; Calcium; Carrier Proteins; Cell Membrane Permeability; Cyclic AMP; Cyclic GMP; Dictyostelium; Electric Stimulation; Guanylate Cyclase; Intracellular Signaling Peptides and Proteins; Kinetics; Second Messenger Systems	1992
Lithium, an inhibitor of cAMP-induced inositol 1,4,5-trisphosphate accumulation in Dictyostelium discoideum, inhibits activation of guanine-nucleotide-binding regulatory proteins, reduces activation of adenylylcyclase, but potentiates activation of guanyl European journal of biochemistry, 1992, Oct-01, Volume: 209, Issue:1 Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylate Cyclase; Inositol 1,4,5-Trisphosphate; Lithium; Second Messenger Systems; Signal Transduction	1992
Nitric oxide-releasing compounds inhibit Dictyostelium discoideum aggregation without altering cGMP production. FEBS letters, 1992, Dec-07, Volume: 314, Issue:1 Topics: Animals; Antihypertensive Agents; Cyclic AMP; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Molsidomine; Morphogenesis; Nitric Oxide; Nitroprusside; Vasodilator Agents	1992
Evidence of cyclic GMP may regulate the association of myosin II heavy chain with the cytoskeleton by inhibiting its phosphorylation. Journal of cell science, 1991, Volume: 98 ( Pt 4) Topics: Animals; Antibodies, Monoclonal; Cyclic AMP; Cyclic GMP; Cytoskeleton; Cytosol; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Hybridomas; Immunoblotting; Models, Biological; Myosins; Phosphorylation	1991
Mutant analysis suggests that cyclic GMP mediates the cyclic AMP-induced Ca2+ uptake in Dictyostelium. Journal of cell science, 1991, Volume: 99 ( Pt 1) Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Dictyostelium; Inositol 1,4,5-Trisphosphate; Mutation	1991
Molecular genetic analysis of two G alpha protein subunits in Dictyostelium. The Journal of biological chemistry, 1991, Jan-15, Volume: 266, Issue:2 Topics: Blotting, Southern; Blotting, Western; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Folic Acid; Fungal Proteins; Genes, Fungal; Genetic Vectors; GTP-Binding Proteins; Guanylate Cyclase; Mutation; Signal Transduction	1991
Reducing reagent-induced activation of guanylate cyclase in the cellular slime mold, Dictyostelium discoideum. Journal of biochemistry, 1991, Volume: 110, Issue:6 Topics: Animals; Carbazoles; Cyclic GMP; Dictyostelium; Dimercaprol; Enzyme Activation; Folic Acid; Guanylate Cyclase; Indicators and Reagents; Indole Alkaloids; Oxidation-Reduction; Protein Kinase C	1991
Dictyostelium discoideum lipids modulate cell-cell cohesion and cyclic AMP signaling. Molecular and cellular biology, 1991, Volume: 11, Issue:1 Topics: Adenylyl Cyclases; Caffeine; Cell Aggregation; Cell Communication; Cell Differentiation; Cell Membrane; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Membrane Lipids	1991
Pertussis toxin inhibits cAMP-induced desensitization of adenylate cyclase in Dictyostelium discoideum. Molecular and cellular biochemistry, 1990, Feb-09, Volume: 92, Issue:2 Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Membrane; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Down-Regulation; Enzyme Activation; Pertussis Toxin; Phosphorylation; Receptors, Cyclic AMP; Virulence Factors, Bordetella	1990
Normal chemotaxis in Dictyostelium discoideum cells with a depolarized plasma membrane potential. Journal of cell science, 1990, Volume: 95 ( Pt 1) Topics: Cell Membrane; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Ion Channel Gating; Membrane Potentials; Signal Transduction	1990
Cyclic GMP-activated protein kinase from Dictyostelium discoideum. Biochimica et biophysica acta, 1990, Jul-12, Volume: 1053, Issue:2-3 Topics: Chromatography; Cyclic GMP; Dictyostelium; Enzyme Activation; Molecular Weight; Protein Kinases; Substrate Specificity	1990
Effects of DNA and synthetic oligodeoxyribonucleotides on the binding properties of a cGMP-binding protein from Dictyostelium discoideum. Biochimica et biophysica acta, 1990, Sep-03, Volume: 1040, Issue:2 Topics: Carrier Proteins; Chromatography, Affinity; Cyclic GMP; Dictyostelium; DNA; Intracellular Signaling Peptides and Proteins; Kinetics; Oligodeoxyribonucleotides; Structure-Activity Relationship	1990
Chemoattractant-induced membrane hyperpolarization in Dictyostelium discoideum. A possible role for cyclic GMP. FEBS letters, 1990, Nov-26, Volume: 275, Issue:1-2 Topics: Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Diethylstilbestrol; Membrane Potentials; Mutation; Potassium; Quinine; Starvation	1990
Sequence organization and gene expression of pGD1, a plasmid found in a wild isolate of Dictyostelium. Nucleic acids research, 1989, Feb-25, Volume: 17, Issue:4 Topics: Amino Acid Sequence; Base Sequence; Blotting, Northern; Cyclic AMP; Cyclic GMP; Dictyostelium; Genes, Fungal; Molecular Sequence Data; Plasmids; Restriction Mapping; Transcription, Genetic	1989
Regulatory properties of magnesium-dependent guanylate cyclase in Dictyostelium discoideum membranes. The Journal of biological chemistry, 1989, Mar-15, Volume: 264, Issue:8 Topics: Adenine Nucleotides; Calcium; Cell Membrane; Cyclic GMP; Dictyostelium; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylate Cyclase; Hydrogen-Ion Concentration; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Magnesium; Thionucleotides	1989
Spike-shaped oscillations in the absence of measurable changes in cyclic AMP concentration in a mutant of Dictyostelium discoideum. Journal of cell science, 1987, Volume: 87 ( Pt 5) Topics: Cell Communication; Cell Differentiation; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dictyostelium; Periodicity; Spectrophotometry	1987
Signal transduction, chemotaxis, and cell aggregation in Dictyostelium discoideum cells without myosin heavy chain. Developmental biology, 1988, Volume: 128, Issue:1 Topics: Actins; Calcium; Cations, Divalent; Chemotaxis; Cyclic AMP; Cyclic GMP; Cytoskeleton; Dictyostelium; Magnesium; Mutation; Myosins; Receptors, Cyclic AMP	1988
Characterization of revertants of stmF mutants of Dictyostelium discoideum: evidence that stmF is the structural gene of the cGMP-specific phosphodiesterase. Developmental genetics, 1986, Volume: 6, Issue:3 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Cyclic GMP; Dictyostelium; Genes; Genes, Fungal; Kinetics; Mutation; Phenotype	1986
Adaptation to chemotactic cyclic AMP signals in Dictyostelium involves the G-protein. Journal of cell science, 1987, Volume: 88 ( Pt 4) Topics: Adaptation, Physiological; Calcium; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Inosine Triphosphate; Inositol 1,4,5-Trisphosphate; Inositol Phosphates	1987
Studies of cell-surface glorin receptors, glorin degradation, and glorin-induced cellular responses during development of Polysphondylium violaceum. Experimental cell research, 1988, Volume: 179, Issue:2 Topics: Chemoreceptor Cells; Chemotactic Factors; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Dipeptides; Kinetics; Lactams; Light; Molecular Weight; Myxomycetes; Scattering, Radiation	1988
Reduced cAMP secretion in Dictyostelium discoideum mutant HB3. Developmental biology, 1988, Volume: 130, Issue:2 Topics: Adenylyl Cyclases; Cell Aggregation; Cell Differentiation; Chemotaxis; Cyclic AMP; Cyclic GMP; Cytoplasm; Dictyostelium; Receptors, Cyclic AMP	1988
cAMP activates adenylate and guanylate cyclase of Dictyostelium discoideum cells by binding to different classes of cell-surface receptors. A study with extracellular Ca2+. Biochimica et biophysica acta, 1985, Sep-30, Volume: 846, Issue:3 Topics: Adenylyl Cyclases; Calcium; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Guanylate Cyclase; Kinetics; Receptors, Cyclic AMP	1985
Postaggregative differentiation induction by cyclic AMP in Dictyostelium: intracellular transduction pathway and requirement for additional stimuli. Developmental biology, 1986, Volume: 118, Issue:1 Topics: Adenylyl Cyclases; Antigens, Fungal; Calcium; Cell Aggregation; Cell Differentiation; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Gene Expression Regulation; Guanylate Cyclase; Ornithine Decarboxylase; Phosphorylases; Starvation	1986
Developmental regulation of the pathways of folate-receptor-mediated stimulation of cAMP and cGMP synthesis in Dictyostelium discoideum. Differentiation; research in biological diversity, 1986, Volume: 32, Issue:3 Topics: Adenylyl Cyclases; Carrier Proteins; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Folate Receptors, GPI-Anchored; Folic Acid; Folic Acid Antagonists; Guanylate Cyclase; Kinetics; Receptors, Cell Surface	1986
Aberrant transmembrane signal transduction in Dictyostelium cells expressing a mutated ras gene. Proceedings of the National Academy of Sciences of the United States of America, 1987, Volume: 84, Issue:14 Topics: Adenylyl Cyclases; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Fungal Proteins; Guanylate Cyclase; Morphogenesis; Oncogenes; ras Proteins; Transformation, Genetic	1987
Differential effects of stimulus termination on excitation and desensitization of folic acid receptors and guanylate cyclase in Dictyostelium discoideum. Biochimica et biophysica acta, 1987, Aug-19, Volume: 930, Issue:1 Topics: Aminohydrolases; Carrier Proteins; Cyclic GMP; Dictyostelium; Folate Receptors, GPI-Anchored; Folic Acid; GTP-Binding Proteins; Guanylate Cyclase; Kinetics; Methotrexate; Protein Conformation; Protozoan Proteins; Receptors, Cell Surface	1987
Differential effects of temperature on cAMP-induced excitation, adaptation, and deadaptation of adenylate and guanylate cyclase in Dictyostelium discoideum. The Journal of cell biology, 1987, Volume: 105, Issue:5 Topics: Acclimatization; Adenylyl Cyclases; Bucladesine; Cyclic AMP; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Kinetics	1987
A magnesium-dependent guanylate cyclase in cell-free preparations of Dictyostelium discoideum. Biochemical and biophysical research communications, 1988, Jan-15, Volume: 150, Issue:1 Topics: Adenosine Triphosphate; Adenylyl Imidodiphosphate; Calcium; Cyclic GMP; Dictyostelium; Enzyme Activation; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylate Cyclase; Magnesium; Manganese; Thionucleotides	1988
cAMP induces a transient elevation of cGMP levels during early culmination of Dictyostelium minutum. Cell differentiation, 1985, Volume: 16, Issue:1 Topics: Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium	1985
Inositol 1,4,5-trisphosphate induces cyclic GMP formation in Dictyostelium discoideum. Biochemical and biophysical research communications, 1985, Aug-15, Volume: 130, Issue:3 Topics: Calcium; Cell Membrane Permeability; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Kinetics; Models, Biological; Sugar Phosphates	1985
Cyclic nucleotide specificity of the activator and catalytic sites of a cGMP-stimulated cGMP phosphodiesterase from Dictyostelium discoideum. European journal of biochemistry, 1985, Aug-15, Volume: 151, Issue:1 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Binding Sites; Catalysis; Cyclic GMP; Dictyostelium; Enzyme Activation; Hydrolysis; Models, Chemical; Protein Binding; Stereoisomerism; Substrate Specificity	1985
The specificity of the cAMP receptor mediating activation of adenylate cyclase in Dictyostelium discoideum. Developmental biology, 1986, Volume: 114, Issue:2 Topics: Adenylyl Cyclases; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Dose-Response Relationship, Drug; Enzyme Activation; Receptors, Cyclic AMP	1986
TMB-8 inhibits respiration and cyclic GMP formation in Dictyostelium discoideum. Journal of cell science, 1985, Volume: 79 Topics: Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid; Gallic Acid; Oxygen Consumption	1985
Inositol 1,4,5-triphosphate induces calcium release from a non- mitochondrial pool in amoebae of Dictyostelium. Biochimica et biophysica acta, 1986, Aug-01, Volume: 887, Issue:3 Topics: Actins; Adenosine Triphosphate; Animals; Calcium; Cell Compartmentation; Cell Membrane Permeability; Cyclic GMP; Dictyostelium; Endoplasmic Reticulum; Inositol 1,4,5-Trisphosphate; Inositol Phosphates; Mitochondria; Receptors, Cell Surface; Sugar Phosphates	1986
Identification of multiple cyclic AMP-binding proteins in developing Dictyostelium discoideum cells. The Journal of biological chemistry, 1986, Aug-15, Volume: 261, Issue:23 Topics: Adenosine Monophosphate; Carrier Proteins; Cyclic AMP; Cyclic AMP Receptor Protein; Cyclic GMP; Dictyostelium; Molecular Weight; Substrate Specificity	1986
Immunohistochemical localization of cyclic AMP, cyclic GMP and calmodulin in Dictyostelium discoideum. Cell biology international reports, 1980, Volume: 4, Issue:7 Topics: Calcium-Binding Proteins; Calmodulin; Cell Nucleus; Cyclic AMP; Cyclic GMP; Cytoplasm; Dictyostelium; Fluorescent Antibody Technique	1980
Localization of cyclic nucleotide phosphodiesterase in the multicellular stages of Dictyostelium discoideum. Differentiation; research in biological diversity, 1980, Volume: 16, Issue:3 Topics: 2',3'-Cyclic-Nucleotide Phosphodiesterases; Cell Compartmentation; Cell Cycle; Cyclic AMP; Cyclic GMP; Dictyostelium; Phosphoric Diester Hydrolases	1980
Regulation by guanosine 3':5'-cyclic monophosphate of phospholipid methylation during chemotaxis in Dictyostelium discoideum. Proceedings of the National Academy of Sciences of the United States of America, 1980, Volume: 77, Issue:12 Topics: Chemotaxis; Cyclic GMP; Dictyostelium; Membrane Fluidity; Methylation; Phospholipids; Purine Nucleotides	1980
Cell differentiation in the absence of intracellular cyclic AMP pulses in Dictyostelium discoideum. Developmental biology, 1981, Jul-15, Volume: 85, Issue:1 Topics: Cell Differentiation; Cells, Cultured; Clone Cells; Cyclic AMP; Cyclic GMP; Dictyostelium	1981
Specificity of the cyclic GMP-binding activity and of a cyclic GMP-dependent cyclic GMP phosphodiesterase in Dictyostelium discoideum. Molecular and cellular endocrinology, 1982, Volume: 25, Issue:2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Binding Sites; Carrier Proteins; Cyclic GMP; Dictyostelium; Enzyme Activation; Enzyme Inhibitors; Substrate Specificity	1982
Streamers: chemotactic mutants of Dictyostelium discoideum with altered cyclic GMP metabolism. Journal of general microbiology, 1981, Volume: 127, Issue:2 Topics: Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Mutation; Phosphoric Diester Hydrolases	1981
Membrane sites regulating developmental gene expression in Dictyostelium discoideum. Cell, 1982, Volume: 28, Issue:4 Topics: Cell Communication; Cell Membrane; Cyclic AMP; Cyclic GMP; Dictyostelium; Edetic Acid; Enzyme Induction; Gene Expression Regulation; Immunoglobulin Fab Fragments; UTP-Glucose-1-Phosphate Uridylyltransferase	1982
Nonequilibrium kinetics of a cyclic GMP-binding protein in Dictyostelium discoideum. The Journal of cell biology, 1982, Volume: 94, Issue:2 Topics: Carrier Proteins; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Induction; Intracellular Signaling Peptides and Proteins; Kinetics; Phosphoric Diester Hydrolases; Receptors, Cell Surface	1982
Cellular responsiveness to cyclic AMP in a phosphodiesterase-defective mutant of Dictyostelium discoideum. Cell differentiation, 1982, Volume: 11, Issue:3 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Cell Aggregation; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Mutation	1982
An intracellular modulator of the 3'5'-cGMP hydrolysis in growing Dictyostelium discoideum amoebae. European journal of biochemistry, 1982, Volume: 125, Issue:2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Cell Membrane; Cyclic GMP; Cytosol; Dictyostelium; Hydrolysis; Mutation	1982
Evidence for a messenger function of cyclic GMP during phosphodiesterase induction in Dictyostelium discoideum. Journal of bacteriology, 1982, Volume: 152, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Carrier Proteins; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Induction; Folic Acid; Intracellular Signaling Peptides and Proteins; Pterins	1982
Evidence that intracellular cGMP is involved in regulating the extracellular cAMP phosphodiesterase and its specific inhibitor in Dictyostelium discoideum. Developmental biology, 1982, Volume: 93, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid; Glycoproteins; Intracellular Fluid; Phosphodiesterase Inhibitors	1982
Altered cGMP-phosphodiesterase activity in chemotactic mutants of Dictyostelium discoideum. FEBS letters, 1982, Oct-18, Volume: 147, Issue:2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Folic Acid; Kinetics; Mutation	1982
Excitation, adaptation, and deadaptation of the cAMP-mediated cGMP response in Dictyostelium discoideum. The Journal of cell biology, 1983, Volume: 96, Issue:2 Topics: Cell Aggregation; Cell Membrane; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Kinetics; Receptors, Cyclic AMP	1983
A study on sensing and adaptation in Dictyostelium discoideum: guanosine 3',5'-phosphate accumulation and light-scattering responses. The Journal of cell biology, 1983, Volume: 96, Issue:6 Topics: Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Light; Mathematics; Scattering, Radiation	1983
Binding of cAMP derivatives to Dictyostelium discoideum cells. Activation mechanism of the cell surface cAMP receptor. The Journal of biological chemistry, 1983, Aug-25, Volume: 258, Issue:16 Topics: Binding, Competitive; Cyclic AMP; Cyclic GMP; Dictyostelium; Models, Molecular; Receptors, Cyclic AMP; Surface Properties	1983
Relationship between adaptation of the folic acid and the cAMP mediated cGMP response in Dictyostelium. Biochemical and biophysical research communications, 1983, Aug-30, Volume: 115, Issue:1 Topics: Acclimatization; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid; Kinetics; Species Specificity	1983
Caffeine blocks activation of cyclic AMP synthesis in Dictyostelium discoideum. Developmental biology, 1984, Volume: 101, Issue:1 Topics: Adenylyl Cyclases; Caffeine; Calcimycin; Cell Survival; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation	1984
Transient kinetics of a cGMP-dependent cGMP-specific phosphodiesterase from Dictyostelium discoideum. The Journal of cell biology, 1984, Volume: 98, Issue:2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Cyclic GMP; Dictyostelium; Enzyme Activation; Kinetics; Mathematics; Models, Biological	1984
Aberrant cGMP-binding activity in non-chemotactic Dictyostelium discoideum mutants. Biochimica et biophysica acta, 1995, Aug-31, Volume: 1268, Issue:2 Topics: Animals; Binding Sites; Cyclic GMP; Dictyostelium; Kinetics; Mutation	1995
Regulatory role of the G alpha 1 subunit in controlling cellular morphogenesis in Dictyostelium. Development (Cambridge, England), 1994, Volume: 120, Issue:12 Topics: Animals; Blotting, Western; Cell Differentiation; Cyclic AMP; Cyclic GMP; Dictyostelium; Gene Expression; Genes, Protozoan; GTP-Binding Proteins; Morphogenesis; Phenotype; Precipitin Tests; Signal Transduction	1994
Non-chemotactic Dictyostelium discoideum mutants with altered cGMP signal transduction. The Journal of cell biology, 1993, Volume: 123, Issue:6 Pt 1 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Chemotaxis; Cyclic GMP; Dictyostelium; Folic Acid; Genes, Fungal; Genetic Linkage; GTP-Binding Proteins; Guanylate Cyclase; Inositol 1,4,5-Trisphosphate; Mutation; Second Messenger Systems; Signal Transduction	1993
Endogenous ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase that is not regulated by nitric oxide in Dictyostelium discoideum. Cellular signalling, 1993, Volume: 5, Issue:6 Topics: Adenosine Diphosphate; Animals; Cyclic GMP; Cytosol; Dictyostelium; Genetic Linkage; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanylate Cyclase; Nitric Oxide; Peptide Fragments; Peptide Mapping	1993
A model for cAMP-mediated cGMP response in Dictyostelium discoideum. Molecular biology of the cell, 1994, Volume: 5, Issue:5 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Adaptation, Physiological; Animals; Calcium; Cell Membrane; Computer Simulation; Cyclic AMP; Cyclic GMP; Dictyostelium; Extracellular Space; Guanylate Cyclase; Inositol Phosphates; Intracellular Fluid; Kinetics; Models, Biological; Mutation; Receptors, Cyclic AMP	1994
G-protein assays in Dictyostelium. Methods in enzymology, 1994, Volume: 237 Topics: Animals; Cell Membrane; Cyclic AMP; Cyclic GMP; Dictyostelium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylate Cyclase; Indicators and Reagents; Inositol 1,4,5-Trisphosphate; Kinetics; Phosphorus Radioisotopes; Protein Binding; Radioisotope Dilution Technique; Sulfur Radioisotopes; Tritium; Type C Phospholipases	1994
The G alpha subunit G alpha 4 couples to pterin receptors and identifies a signaling pathway that is essential for multicellular development in Dictyostelium. Proceedings of the National Academy of Sciences of the United States of America, 1994, Oct-25, Volume: 91, Issue:22 Topics: Adenylyl Cyclases; Animals; Biopterins; Carrier Proteins; Cell Division; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Fluorescent Antibody Technique; Folate Receptors, GPI-Anchored; Folic Acid; GTP-Binding Proteins; Guanylate Cyclase; Macromolecular Substances; Neopterin; Protozoan Proteins; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Signal Transduction	1994
Two cAMP receptors activate common signaling pathways in Dictyostelium. Molecular biology of the cell, 1994, Volume: 5, Issue:6 Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic GMP; Dictyostelium; Gene Deletion; Genes, Fungal; Genes, Protozoan; GTP-Binding Proteins; Receptors, Cyclic AMP; Signal Transduction; Thionucleotides	1994
Rapid translocation of myosin II in vegetative Dictyostelium amoebae during chemotactic stimulation by folic acid. Cell structure and function, 1994, Volume: 19, Issue:3 Topics: Actins; Animals; Biological Transport; Calcimycin; Calcium; Chemotaxis; Cyclic GMP; Cytoskeleton; Dictyostelium; Folic Acid; Fungal Proteins; Microscopy, Fluorescence; Myosins	1994
Regulation of myosin regulatory light chain phosphorylation via cyclic GMP during chemotaxis of Dictyostelium. Journal of cell science, 1994, Volume: 107 ( Pt 7) Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Chemotaxis; Cyclic GMP; Cytoskeleton; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Homeostasis; Models, Biological; Molecular Weight; Mutation; Myosin-Light-Chain Kinase; Myosins; Phosphorus Radioisotopes; Phosphorylation; Species Specificity	1994
The role of cGMP in photosensory and thermosensory transduction in Dictyostelium discoideum. Microbiology (Reading, England), 1994, Volume: 140 ( Pt 7) Topics: Animals; Cell Movement; Cyclic GMP; Dictyostelium; Hot Temperature; Light; Models, Biological; Mutation; Phenotype; Photoreceptor Cells, Invertebrate; Signal Transduction; Thermoreceptors	1994
Role of cyclic GMP in signal transduction to cytoskeletal myosin. Symposia of the Society for Experimental Biology, 1993, Volume: 47 Topics: Actins; Animals; Cyclic AMP; Cyclic GMP; Cytoskeleton; Dictyostelium; Models, Biological; Myosins; Phosphorylation; Receptors, Cyclic AMP; Signal Transduction	1993
Extracellular cAMP is sufficient to restore developmental gene expression and morphogenesis in Dictyostelium cells lacking the aggregation adenylyl cyclase (ACA). Genes & development, 1993, Volume: 7, Issue:11 Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic GMP; Dictyostelium; Gene Deletion; Gene Expression Regulation, Fungal; Genes, Fungal; Kinetics; Morphogenesis; RNA, Messenger; Spores, Fungal; Time Factors	1993
The role of cyclic GMP in regulating myosin during chemotaxis of Dictyostelium: evidence from a mutant lacking the normal cyclic GMP response to cyclic AMP. Journal of cell science, 1993, Volume: 106 ( Pt 2) Topics: Actins; Animals; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Fungal Proteins; Mutation; Myosins; Phosphorylation; Protozoan Proteins	1993
Platelet activating factor modulates signal transduction in Dictyostelium. Journal of cell science, 1993, Volume: 104 ( Pt 1) Topics: Animals; Calcium; Cyclic AMP; Cyclic GMP; Dictyostelium; Nephelometry and Turbidimetry; Platelet Activating Factor; Signal Transduction; Stereoisomerism	1993
Protection against osmotic stress by cGMP-mediated myosin phosphorylation. Science (New York, N.Y.), 1996, Jan-12, Volume: 271, Issue:5246 Topics: Actin Cytoskeleton; Actins; Animals; Cyclic GMP; Cytoplasm; Dictyostelium; Glucose; Guanylate Cyclase; Myosins; Osmotic Pressure; Phosphorylation; Pseudopodia; Threonine; Water-Electrolyte Balance	1996
cGMP accumulation induced by hypertonic stress in Dictyostelium discoideum. The Journal of biological chemistry, 1996, Mar-08, Volume: 271, Issue:10 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Cyclic GMP; Dictyostelium; Glucose; Hypertonic Solutions; Kinetics; Mutation; Potassium Chloride; Stress, Physiological; Time Factors	1996
Chemoattractant-mediated increases in cGMP induce changes in Dictyostelium myosin II heavy chain-specific protein kinase C activities. The Journal of cell biology, 1996, Volume: 134, Issue:4 Topics: Alkaloids; Animals; Biological Transport; Calcium-Calmodulin-Dependent Protein Kinases; Carbazoles; Cell Membrane; Chemotactic Factors; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Cytoskeleton; Cytosol; Dictyostelium; Enzyme Inhibitors; Indoles; Kinetics; Mutation; Myosin Heavy Chains; Myosins; Phosphorylation; Protozoan Proteins	1996
Regulation of guanylyl cyclase by a cGMP-binding protein during chemotaxis in Dictyostelium discoideum. The Journal of biological chemistry, 1996, Sep-27, Volume: 271, Issue:39 Topics: Adenosine Triphosphate; Animals; Azides; Carrier Proteins; Chemotaxis; Cyclic GMP; Dictyostelium; DNA; Fungal Proteins; Guanylate Cyclase; Intracellular Signaling Peptides and Proteins; Phosphoproteins; Protein Kinases; Signal Transduction	1996
Guanylate cyclase activity in permeabilized Dictyostelium discoideum cells. Journal of cellular biochemistry, 1996, Mar-01, Volume: 60, Issue:3 Topics: Animals; Calcium; Cell Fractionation; Cell Membrane Permeability; Cyclic GMP; Dictyostelium; Electroporation; Enzyme Activation; Enzyme Reactivators; Guanosine 5'-O-(3-Thiotriphosphate); Guanosine Triphosphate; Guanylate Cyclase; Half-Life; Inositol 1,4,5-Trisphosphate; Solubility	1996
A novel cytosolic regulator, Pianissimo, is required for chemoattractant receptor and G protein-mediated activation of the 12 transmembrane domain adenylyl cyclase in Dictyostelium. Genes & development, 1997, Dec-01, Volume: 11, Issue:23 Topics: Actins; Adenylyl Cyclases; Amino Acid Sequence; Animals; Chemotactic Factors; Chemotaxis; Cloning, Molecular; Cyclic GMP; Cytosol; Dictyostelium; Enzyme Activation; Fungal Proteins; Gene Expression; Genes, Fungal; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Molecular Sequence Data; Protozoan Proteins; Saccharomyces cerevisiae; Schizosaccharomyces; Sequence Homology, Amino Acid	1997
Chemotactic and osmotic signals share a cGMP transduction pathway in Dictyostelium discoideum. FEBS letters, 1998, Mar-13, Volume: 424, Issue:3 Topics: Animals; Carrier Proteins; Chemotaxis; Cyclic GMP; Dictyostelium; GTP-Binding Proteins; Inositol 1,4,5-Trisphosphate; Intracellular Signaling Peptides and Proteins; Mutation; Osmosis; Receptors, Cyclic AMP; Signal Transduction	1998
cGMP potentiates receptor-stimulated Ca2+ influx in Dictyostelium discoideum. Biochimica et biophysica acta, 1998, Mar-12, Volume: 1402, Issue:1 Topics: Animals; Calcium; Calcium Channels; Calcium Radioisotopes; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Kinetics; Models, Biological; Receptors, Cyclic AMP; Signal Transduction	1998
MLCK-A, an unconventional myosin light chain kinase from Dictyostelium, is activated by a cGMP-dependent pathway. Proceedings of the National Academy of Sciences of the United States of America, 1998, Oct-27, Volume: 95, Issue:22 Topics: Actomyosin; Animals; Concanavalin A; Cyclic GMP; Dictyostelium; Enzyme Activation; Kinetics; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Protozoan Proteins	1998
Regulation of Dictyostelium protein-tyrosine phosphatase-3 (PTP3) through osmotic shock and stress stimulation and identification of pp130 as a PTP3 substrate. The Journal of biological chemistry, 1999, Apr-23, Volume: 274, Issue:17 Topics: Actins; Animals; Biological Transport; Catalysis; Cyclic GMP; Dictyostelium; Enzyme Activation; Guanylate Cyclase; Intracellular Signaling Peptides and Proteins; Osmotic Pressure; Oxidative Stress; Phosphorylation; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protein Tyrosine Phosphatases; Protozoan Proteins; Substrate Specificity; Tyrosine	1999
Identification and characterization of DdPDE3, a cGMP-selective phosphodiesterase from Dictyostelium. The Biochemical journal, 2001, Feb-01, Volume: 353, Issue:Pt 3 Topics: 1-Methyl-3-isobutylxanthine; 3',5'-Cyclic-GMP Phosphodiesterases; Amino Acid Sequence; Animals; Base Sequence; Catalytic Domain; Cations, Divalent; Cloning, Molecular; Cyclic GMP; Dictyostelium; DNA, Recombinant; Escherichia coli; Gene Expression Regulation, Enzymologic; Molecular Sequence Data; RNA, Messenger; Sequence Homology, Amino Acid	2001
Guanylate cyclase in Dictyostelium discoideum with the topology of mammalian adenylate cyclase. The Biochemical journal, 2001, Mar-15, Volume: 354, Issue:Pt 3 Topics: Adenylyl Cyclases; Amino Acid Sequence; Animals; Cell Aggregation; Cells, Cultured; Cloning, Molecular; Cyclic GMP; Dictyostelium; Gene Deletion; Guanylate Cyclase; Membrane Proteins; Molecular Sequence Data; Phylogeny; Protein Conformation; Protein Structure, Tertiary; Protozoan Proteins; Sequence Homology, Amino Acid	2001
A cell number-counting factor regulates group size in Dictyostelium by differentially modulating cAMP-induced cAMP and cGMP pulse sizes. The Journal of biological chemistry, 2001, Jul-20, Volume: 276, Issue:29 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Biological Factors; Cyclic AMP; Cyclic GMP; Dictyostelium; GTP-Binding Proteins; Protozoan Proteins; Receptors, Cyclic AMP; Signal Transduction	2001
Lysophosphatidic acid- and Gbeta-dependent activation of Dictyostelium MAP kinase ERK2. Biochemical and biophysical research communications, 2001, Apr-06, Volume: 282, Issue:3 Topics: Animals; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Heterotrimeric GTP-Binding Proteins; Lysophospholipids; Mitogen-Activated Protein Kinase 1; Receptors, Cell Surface; Receptors, G-Protein-Coupled; Receptors, Lysophosphatidic Acid; Signal Transduction	2001
Identification of four candidate cGMP targets in Dictyostelium. Proceedings of the National Academy of Sciences of the United States of America, 2002, May-14, Volume: 99, Issue:10 Topics: Amino Acid Sequence; Animals; Carrier Proteins; Cyclic GMP; Dictyostelium; Gene Expression; Intracellular Signaling Peptides and Proteins; Molecular Sequence Data; Protozoan Proteins; Sequence Homology, Amino Acid	2002
A secreted cell number counting factor represses intracellular glucose levels to regulate group size in dictyostelium. The Journal of biological chemistry, 2002, Oct-18, Volume: 277, Issue:42 Topics: Animals; Blotting, Western; Cell Adhesion; Cell Movement; Cells, Cultured; Computer Simulation; Cyclic AMP; Cyclic GMP; Dictyostelium; Glucose; Kinetics; Myosins; Protozoan Proteins; Recombinant Proteins; Signal Transduction; Time Factors	2002
Evidence for a role for the Dictyostelium Rap1 in cell viability and the response to osmotic stress. Journal of cell science, 2002, Sep-15, Volume: 115, Issue:Pt 18 Topics: Animals; Cell Division; Cell Size; Cell Survival; Cyclic GMP; Dictyostelium; Edetic Acid; Gene Expression Regulation; Guanylate Cyclase; Osmotic Pressure; Protein Binding; Protein Structure, Tertiary; ral Guanine Nucleotide Exchange Factor; rap1 GTP-Binding Proteins; RNA, Antisense; Sorbitol; Stress, Physiological; Temperature	2002
A novel cGMP signalling pathway mediating myosin phosphorylation and chemotaxis in Dictyostelium. The EMBO journal, 2002, Sep-02, Volume: 21, Issue:17 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Carrier Proteins; Chemotaxis; Cyclic GMP; Cytoskeleton; Dictyostelium; Guanylate Cyclase; Intracellular Signaling Peptides and Proteins; Myosin Type II; Phosphorylation; Protein Processing, Post-Translational; Protozoan Proteins; Second Messenger Systems	2002
Establishing direction during chemotaxis in eukaryotic cells. Biophysical journal, 2002, Volume: 83, Issue:3 Topics: Animals; Biophysical Phenomena; Biophysics; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Eukaryotic Cells; Hydrogen-Ion Concentration; Models, Biological; Mutation; Neutrophils; Protein Structure, Tertiary; Time Factors	2002
Identification of a novel type of cGMP phosphodiesterase that is defective in the chemotactic stmF mutants. Molecular biology of the cell, 2002, Volume: 13, Issue:11 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Amino Acid Sequence; Animals; Chemotaxis; Cyclic GMP; Dictyostelium; Enzyme Activation; Gene Expression Regulation, Developmental; Humans; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Recombinant Fusion Proteins; Sequence Alignment	2002
Identification and characterization of two unusual cGMP-stimulated phoshodiesterases in dictyostelium. Molecular biology of the cell, 2002, Volume: 13, Issue:11 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Amino Acid Sequence; Animals; Cyclic AMP; Cyclic GMP; Dictyostelium; Gene Targeting; Humans; Molecular Sequence Data; Phenotype; Protein Structure, Tertiary; Sequence Alignment	2002
cGMP signalling: different ways to create a pathway. Trends in genetics : TIG, 2003, Volume: 19, Issue:3 Topics: Animals; Cyclic GMP; Dictyostelium; Evolution, Molecular; Guanylate Cyclase; Models, Biological; Phylogeny; Protein Structure, Tertiary; Second Messenger Systems; Signal Transduction	2003
A STAT-regulated, stress-induced signalling pathway in Dictyostelium. Journal of cell science, 2003, Jul-15, Volume: 116, Issue:Pt 14 Topics: Active Transport, Cell Nucleus; Animals; Blotting, Northern; Blotting, Western; Cell Cycle Proteins; Cell Nucleus; Cyclic AMP; Cyclic GMP; Dictyostelium; Dose-Response Relationship, Drug; Green Fluorescent Proteins; Immunohistochemistry; Luminescent Proteins; Models, Biological; Mutation; Oligonucleotide Array Sequence Analysis; Osmosis; Oxidative Stress; Phosphorylation; Protein Transport; Protozoan Proteins; Signal Transduction; STAT Transcription Factors; Time Factors; Trans-Activators; Transcription, Genetic; Tyrosine	2003
The signal to move: D. discoideum go orienteering. Science (New York, N.Y.), 2003, Jun-06, Volume: 300, Issue:5625 Topics: Actins; Animals; Cell Polarity; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Heterotrimeric GTP-Binding Proteins; Myosin Type II; Phosphatidylinositol 3-Kinases; Phosphoric Monoester Hydrolases; Phosphorylation; Protozoan Proteins; Pseudopodia; PTEN Phosphohydrolase; Receptors, Cyclic AMP; Signal Transduction; Tumor Suppressor Proteins	2003
Two components of a secreted cell number-counting factor bind to cells and have opposing effects on cAMP signal transduction in Dictyostelium. The Journal of biological chemistry, 2003, Dec-26, Volume: 278, Issue:52 Topics: Animals; Cell Movement; Cells, Cultured; Cyclic AMP; Cyclic GMP; Dictyostelium; Dose-Response Relationship, Drug; Kinetics; Mitogen-Activated Protein Kinase 1; Protein Binding; Protozoan Proteins; Receptors, Cyclic AMP; Recombinant Proteins; Signal Transduction; Time Factors; Ultracentrifugation	2003
Chemoattractant-stimulated calcium influx in Dictyostelium discoideum does not depend on cGMP. Biochimica et biophysica acta, 2003, Oct-13, Volume: 1623, Issue:2-3 Topics: Animals; Calcium Signaling; Cyclic AMP; Cyclic GMP; Dictyostelium; Folic Acid; Genes, Protozoan; Kinetics; Mutation	2003
A G alpha-dependent pathway that antagonizes multiple chemoattractant responses that regulate directional cell movement. Genes & development, 2004, Apr-01, Volume: 18, Issue:7 Topics: Actins; Adenylyl Cyclases; Animals; Cell Membrane; Cell Movement; Cell Polarity; Chemotactic Factors; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Gene Expression Regulation, Developmental; GTP-Binding Proteins; Guanylate Cyclase; Hydrogen-Ion Concentration; Myosins; Phosphatidylinositol 3-Kinases; Phosphatidylinositol Phosphates; Protozoan Proteins; Pseudopodia; Signal Transduction	2004
Developmental control of cAMP-induced Ca2+-influx by cGMP: influx is delayed and reduced in a cGMP-phosphodiesterase D deficient mutant of Dictyostelium discoideum. Cell calcium, 2005, Volume: 37, Issue:1 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Arachidonic Acid; Calcium; Calcium Channels; Calcium Signaling; Cell Membrane; Cyclic AMP; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 5; Dictyostelium; Dose-Response Relationship, Drug; Extracellular Fluid; Mutation; Photic Stimulation; Up-Regulation	2005
Activation of soluble guanylyl cyclase at the leading edge during Dictyostelium chemotaxis. Molecular biology of the cell, 2005, Volume: 16, Issue:2 Topics: Animals; Catalysis; Cell Membrane; Cell Polarity; Chemotaxis; Cyclic AMP; Cyclic GMP; Cytosol; Dictyostelium; Enzyme Activation; Green Fluorescent Proteins; Guanosine Triphosphate; Guanylate Cyclase; Isoenzymes; Magnesium; Manganese; Membrane Fusion; Solubility; Substrate Specificity	2005
RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium. Journal of cell science, 2005, May-01, Volume: 118, Issue:Pt 9 Topics: Actins; Animals; Carrier Proteins; Cell Adhesion; Cell Membrane; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Green Fluorescent Proteins; Mutation; Myosin Type II; Myosins; Phenotype; Plasmids; Protein Binding; Protein Structure, Tertiary; Protein Transport; ras Guanine Nucleotide Exchange Factors; Software; Time Factors	2005
cGMP-phosphodiesterase antagonists inhibit Ca2+-influx in Dictyostelium discoideum and bovine cyclic-nucleotide-gated-channel. European journal of pharmacology, 2005, Apr-18, Volume: 513, Issue:1-2 Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calcium; Cattle; Cell Line; Cyclic AMP; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Dictyostelium; Dose-Response Relationship, Drug; Gene Expression; Humans; Hydrolysis; Imidazoles; Ion Channel Gating; Ion Channels; Membrane Potentials; Mutation; Patch-Clamp Techniques; Piperazines; Purines; Sildenafil Citrate; Sulfones	2005
Evidence that cyclic GMP regulates myosin interaction with the cytoskeleton during chemotaxis of Dictyostelium. Journal of cell science, 1988, Volume: 90 ( Pt 1) Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Actins; Animals; Chemotaxis; Cyclic AMP; Cyclic GMP; Cytoskeleton; Dictyostelium; Models, Biological; Mutation; Myosin Heavy Chains; Myosins; Signal Transduction; Time Factors	1988
Myosin light chain kinase A is activated by cGMP-dependent and cGMP-independent pathways. FEBS letters, 2006, Apr-03, Volume: 580, Issue:8 Topics: Animals; Carrier Proteins; Chemotaxis; Concanavalin A; Cyclic GMP; Cytokinesis; Dictyostelium; Enzyme Activation; Gene Deletion; Intracellular Signaling Peptides and Proteins; Models, Biological; Myosin Light Chains; Myosin-Light-Chain Kinase; Phosphorylation; Signal Transduction	2006
Guanylyl cyclase protein and cGMP product independently control front and back of chemotaxing Dictyostelium cells. Molecular biology of the cell, 2006, Volume: 17, Issue:9 Topics: Actins; Animals; Cell Polarity; Cell Shape; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Mutant Proteins; Myosins; Protein Transport; Receptors, Cytoplasmic and Nuclear; Soluble Guanylyl Cyclase	2006
Delineation of the roles played by RasG and RasC in cAMP-dependent signal transduction during the early development of Dictyostelium discoideum. Molecular biology of the cell, 2006, Volume: 17, Issue:10 Topics: 3-Phosphoinositide-Dependent Protein Kinases; Adenylyl Cyclases; Animals; Animals, Genetically Modified; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Phosphorylation; Protein Serine-Threonine Kinases; Protozoan Proteins; ras Proteins; Signal Transduction	2006
Analysis of signal transduction: formation of cAMP, cGMP, and Ins(1,4,5)P3 in vivo and in vitro. Methods in molecular biology (Clifton, N.J.), 2006, Volume: 346 Topics: Adenylyl Cyclases; Animals; Cyclic AMP; Cyclic GMP; Dictyostelium; GTP-Binding Proteins; Guanosine 5'-O-(3-Thiotriphosphate); Guanylate Cyclase; In Vitro Techniques; Inositol 1,4,5-Trisphosphate; Receptors, Cyclic AMP; Signal Transduction; Type C Phospholipases	2006
Seven Dictyostelium discoideum phosphodiesterases degrade three pools of cAMP and cGMP. The Biochemical journal, 2007, Feb-15, Volume: 402, Issue:1 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Amino Acid Sequence; Animals; Catalytic Domain; Cyclic AMP; Cyclic GMP; Dictyostelium; Hydrolysis; Kinetics; Molecular Sequence Data; Protozoan Proteins; Sequence Alignment; Sequence Homology, Amino Acid	2007
Oscillations of Ca++ concentration during the cell differentiation of Dictyostelium discoideum: their relation to oscillations in cyclic AMP and other components. Differentiation; research in biological diversity, 1986, Volume: 31, Issue:2 Topics: Animals; Calcium; Calcium Signaling; Cell Differentiation; Cell Membrane; Cyclic AMP; Cyclic GMP; Dictyostelium	1986
Developmental morphology and chemotactic responses are dependent on G alpha subunit specificity in Dictyostelium. Developmental biology, 2007, Dec-01, Volume: 312, Issue:1 Topics: Amino Acid Sequence; Animals; Chemotaxis; Cyclic GMP; Dictyostelium; Folic Acid; Gene Expression Regulation, Developmental; GTP-Binding Protein alpha Subunits; Molecular Sequence Data; Phenotype; Protein Subunits; Recombinant Proteins	2007
The role of cGMP and the rear of the cell in Dictyostelium chemotaxis and cell streaming. Journal of cell science, 2008, Jan-01, Volume: 121, Issue:Pt 1 Topics: Animals; Cell Movement; Chemotaxis; Cyclic GMP; Dictyostelium; Guanylate Cyclase; Mutation; Signal Transduction	2008
Arachidonic acid is a chemoattractant for Dictyostelium discoideum cells. Journal of biosciences, 2007, Volume: 32, Issue:7 Topics: Animals; Arachidonic Acid; Calcium; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Egtazic Acid; Mutation	2007
Intramolecular activation mechanism of the Dictyostelium LRRK2 homolog Roco protein GbpC. The Journal of biological chemistry, 2008, Oct-31, Volume: 283, Issue:44 Topics: Amino Acid Sequence; Animals; Chemotaxis; Cyclic GMP; Dictyostelium; Guanosine Triphosphate; Humans; Intracellular Signaling Peptides and Proteins; Leucine-Rich Repeat Serine-Threonine Protein Kinase-2; Models, Biological; Molecular Sequence Data; Mutation; Protein Binding; Protein Serine-Threonine Kinases; Protein Structure, Tertiary; Sequence Homology, Amino Acid; Signal Transduction	2008
Switching direction in electric-signal-induced cell migration by cyclic guanosine monophosphate and phosphatidylinositol signaling. Proceedings of the National Academy of Sciences of the United States of America, 2009, Apr-21, Volume: 106, Issue:16 Topics: Animals; Cell Movement; Cyclic GMP; Dictyostelium; Electricity; Enzyme Inhibitors; Guanylate Cyclase; Intracellular Space; Models, Biological; Mutation; Phosphatidylinositols; Phosphoinositide-3 Kinase Inhibitors; Protein Structure, Tertiary; Protein Transport; Signal Transduction	2009
The ordered extension of pseudopodia by amoeboid cells in the absence of external cues. PloS one, 2009, Volume: 4, Issue:4 Topics: Animals; Cyclic GMP; Dictyostelium; Phospholipases A2; Pseudopodia; Signal Transduction	2009
Differentiation-inducing factor-1 and -2 function also as modulators for Dictyostelium chemotaxis. PloS one, 2009, Aug-17, Volume: 4, Issue:8 Topics: Animals; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Hexanones; Hydrocarbons, Chlorinated	2009
Food searching strategy of amoeboid cells by starvation induced run length extension. PloS one, 2009, Aug-28, Volume: 4, Issue:8 Topics: Animals; Cyclic GMP; Dictyostelium; Feeding Behavior; Phospholipases A2; Signal Transduction; Starvation	2009
Dual regulation of a Dictyostelium STAT by cGMP and Ca2+ signalling. Journal of cell science, 2010, Mar-15, Volume: 123, Issue:Pt 6 Topics: Amino Acid Sequence; Animals; Antibodies, Phospho-Specific; Calcium; Calcium Signaling; Cyclic GMP; Dictyostelium; Intracellular Space; Models, Biological; Molecular Sequence Data; Osmotic Pressure; Phosphorylation; Phosphoserine; Phosphothreonine; Protein Tyrosine Phosphatase, Non-Receptor Type 11; Protozoan Proteins; STAT Transcription Factors; Stress, Physiological	2010
How cells use pseudopods for persistent movement and navigation. Science signaling, 2011, Feb-08, Volume: 4, Issue:159 Topics: Algorithms; Animals; Cell Line, Tumor; Cells, Cultured; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; GTP-Binding Proteins; Humans; Jurkat Cells; Models, Biological; Movement; Neutrophils; Phosphatidylinositol 3-Kinases; Phospholipases A2; Pseudopodia; ras Proteins; Receptors, Cyclic AMP; Signal Transduction	2011
Multiple regulatory mechanisms for the Dictyostelium Roco protein GbpC. The Journal of biological chemistry, 2012, Jan-20, Volume: 287, Issue:4 Topics: Cell Membrane; Cyclic AMP; Cyclic GMP; Cytoplasm; Dictyostelium; Protein Structure, Tertiary; Protein Transport; Protozoan Proteins; Second Messenger Systems	2012
The prokaryote messenger c-di-GMP triggers stalk cell differentiation in Dictyostelium. Nature, 2012, Aug-30, Volume: 488, Issue:7413 Topics: Biological Assay; Cell Differentiation; Cyclic GMP; Dictyostelium; Fruiting Bodies, Fungal; Guanosine Triphosphate; Molecular Sequence Data; Prokaryotic Cells; Protozoan Proteins; RNA, Messenger; Second Messenger Systems	2012
Intracellular photoactivation of caged cGMP induces myosin II and actin responses in motile cells. Integrative biology : quantitative biosciences from nano to macro, 2013, Volume: 5, Issue:12 Topics: Actins; Cell Line; Cyclic GMP; Cytoskeleton; Dictyostelium; Image Processing, Computer-Assisted; Microscopy, Fluorescence; Myosin Type II; Signal Transduction	2013
c-di-GMP induction of Dictyostelium cell death requires the polyketide DIF-1. Molecular biology of the cell, 2015, Feb-15, Volume: 26, Issue:4 Topics: Cell Death; Cyclic GMP; Dictyostelium; Polyketides; Second Messenger Systems; Signal Transduction; Species Specificity	2015
Adenylate cyclase A acting on PKA mediates induction of stalk formation by cyclic diguanylate at the Dictyostelium organizer. Proceedings of the National Academy of Sciences of the United States of America, 2017, 01-17, Volume: 114, Issue:3 Topics: Adenylyl Cyclases; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Cyclic GMP; Dictyostelium; Escherichia coli Proteins; Gene Expression Regulation, Developmental; Genes, Protozoan; Mutation; Phosphorus-Oxygen Lyases; Protozoan Proteins; Signal Transduction; Spores, Protozoan	2017
Cytokinesis D is Mediated by Cortical Flow of Dividing Cells Instead of Chemotaxis. Cells, 2019, 05-17, Volume: 8, Issue:5 Topics: Actin Cytoskeleton; Actins; Calcium; Cell Movement; Cell Tracking; Cells, Cultured; Chemotactic Factors; Chemotaxis; Cyclic AMP; Cyclic GMP; Cytokinesis; Cytoplasm; Dictyostelium; Green Fluorescent Proteins; Interphase; Microscopy, Phase-Contrast; Mitosis; Models, Biological; Pleckstrin Homology Domains	2019
Dynamics of intracellular cGMP during chemotaxis in Dictyostelium cells. Journal of cell science, 2023, 02-01, Volume: 136, Issue:3 Topics: Actomyosin; Chemotaxis; Cyclic GMP; Dictyostelium; Myosin Type II	2023