1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with chloroquine in 9 studies
| Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Studies (chloroquine) | Trials (chloroquine) | Recent Studies (post-2010) (chloroquine) |
|---|---|---|---|---|---|
| 7,666 | 0 | 1,658 | 16,405 | 763 | 4,029 |
| Protein | Taxonomy | 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50) | chloroquine (IC50) |
|---|---|---|---|
| glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase | Plasmodium berghei | 43 | |
| Spike glycoprotein | Betacoronavirus England 1 | 5.47 | |
| Replicase polyprotein 1ab | Betacoronavirus England 1 | 5.47 | |
| Transmembrane protease serine 2 | Homo sapiens (human) | 5.47 | |
| Dihydrofolate reductase | Bos taurus (cattle) | 0.0301 | |
| Amyloid-beta precursor protein | Homo sapiens (human) | 7 | |
| Histidine-rich protein PFHRP-II | Plasmodium falciparum (malaria parasite P. falciparum) | 0.2383 | |
| Procathepsin L | Homo sapiens (human) | 5.47 | |
| Replicase polyprotein 1a | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Replicase polyprotein 1ab | Human coronavirus 229E | 5.47 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Spike glycoprotein | Severe acute respiratory syndrome coronavirus 2 | 3.58 | |
| Replicase polyprotein 1ab | Severe acute respiratory syndrome coronavirus 2 | 6.375 | |
| Ribosyldihydronicotinamide dehydrogenase [quinone] | Homo sapiens (human) | 1.5 | |
| Serine/threonine-protein kinase mTOR | Homo sapiens (human) | 0.27 | |
| Beta-secretase 1 | Homo sapiens (human) | 7 | |
| Spike glycoprotein | Severe acute respiratory syndrome-related coronavirus | 5.47 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 2.503 | |
| Angiotensin-converting enzyme 2 | Homo sapiens (human) | 6.235 | |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | 0.02 | |
| Cysteine proteinase falcipain 2a | Plasmodium falciparum (malaria parasite P. falciparum) | 0.2 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonner, JT; Fong, D | 1 |
| Bush, JM; Cardelli, JA; Ebert, D; Freeze, HH | 1 |
| Cardelli, JA; Miears, D; Richardson, J | 1 |
| Favard-Séréno, C; Ludosky, MA; Ryter, A | 1 |
| Davies, L; Gross, JD; Martin, JB; Satre, M | 1 |
| Baird, JK; Carlton, JM; Collins, WE; del Portillo, HA; Fidock, DA; Fryauff, DJ; McCutchan, TF; Nomura, T; Rathore, D; Su , X; Wellems, TE; Wootton, JC | 1 |
| Brzostowski, JA; Kimmel, AR; Naudé, B; Wellems, TE | 1 |
| de Azevedo, MF; Del Portillo, HA; Fernandez-Becerra, C; Naudé, B; Papakrivos, J; Sá, JM; Wellems, TE; Yamamoto, MM | 1 |
| Papakrivos, J; Sá, JM; Wellems, TE | 1 |
9 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and chloroquine
| Article | Year |
|---|---|
Proteases in cellular slime mold development: evidence for their involvement.
Topics: Amino Acids; Animals; Antipain; Cell Differentiation; Chloroquine; Dictyostelium; Energy Metabolism; Leupeptins; Pepstatins; Peptide Hydrolases; Protease Inhibitors | 1979 |
Sulfated N-linked oligosaccharides affect secretion but are not essential for the transport, proteolytic processing, and sorting of lysosomal enzymes in Dictyostelium discoideum.
Topics: Acetylglucosaminidase; alpha-Mannosidase; beta-Glucosidase; Biological Transport; Chloroquine; Chromatography, Ion Exchange; Dictyostelium; Glucosidases; Kinetics; Lysosomes; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Oligosaccharides; Protein Processing, Post-Translational; Sulfuric Acids | 1990 |
Role of acidic intracellular compartments in the biosynthesis of Dictyostelium lysosomal enzymes. The weak bases ammonium chloride and chloroquine differentially affect proteolytic processing and sorting.
Topics: Acetylglucosaminidase; alpha-Mannosidase; Ammonium Chloride; beta-Glucosidase; Biological Transport; Cell Fractionation; Centrifugation, Density Gradient; Chloroquine; Dictyostelium; Enzyme Precursors; Glucosidases; Golgi Apparatus; Hydrogen-Ion Concentration; Lysosomes; Mannosidases; Mannosyl-Glycoprotein Endo-beta-N-Acetylglucosaminidase; Organelles; Peptide Hydrolases; Vacuoles | 1989 |
Freeze-fracture study of phagocytosis in Dictyostelium discoideum.
Topics: Cell Membrane; Chloroquine; Concanavalin A; Dictyostelium; Freeze Fracturing; Hydrogen-Ion Concentration; Microscopy, Electron; Microspheres; Phagocytosis; Saccharomyces cerevisiae; Sterols | 1981 |
The target of ammonia action in dictyostelium.
Topics: Alkalies; Amines; Ammonia; Animals; Cell Compartmentation; Chloroquine; Cytoplasm; Dictyostelium; Hydrogen-Ion Concentration; Magnetic Resonance Spectroscopy; Morphogenesis; Vacuoles | 1993 |
Evidence for different mechanisms of chloroquine resistance in 2 Plasmodium species that cause human malaria.
Topics: Amino Acid Sequence; Animals; Chloroquine; Codon; Dictyostelium; Drug Resistance; Humans; Molecular Chaperones; Molecular Sequence Data; Mutation; Parasitic Sensitivity Tests; Plasmodium; Sequence Alignment | 2001 |
Dictyostelium discoideum expresses a malaria chloroquine resistance mechanism upon transfection with mutant, but not wild-type, Plasmodium falciparum transporter PfCRT.
Topics: Acids; Amino Acid Sequence; Animals; Antimalarials; Chloroquine; Cytoplasmic Vesicles; Dictyostelium; Drug Resistance, Bacterial; Gene Expression; Membrane Proteins; Membrane Transport Proteins; Molecular Sequence Data; Phenotype; Phylogeny; Plasmodium falciparum; Point Mutation; Protozoan Proteins; Quinidine; Quinine; Quinolines; Transfection | 2005 |
Expression and function of pvcrt-o, a Plasmodium vivax ortholog of pfcrt, in Plasmodium falciparum and Dictyostelium discoideum.
Topics: Animals; Antimalarials; Chloroquine; Dictyostelium; Drug Resistance; Endosomes; Erythrocytes; Gene Expression; Genes, Protozoan; Humans; Inhibitory Concentration 50; Membrane Transport Proteins; Plasmodium falciparum; Plasmodium vivax; Promoter Regions, Genetic; Protozoan Proteins; Transfection; Vacuoles | 2006 |
Functional characterization of the Plasmodium falciparum chloroquine-resistance transporter (PfCRT) in transformed Dictyostelium discoideum vesicles.
Topics: Adenosine Triphosphate; Ammonia; Animals; Antimalarials; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Cell Line, Transformed; Chloroquine; Cytoplasmic Vesicles; Dictyostelium; Hydrogen-Ion Concentration; Ionophores; Macrolides; Membrane Potentials; Membrane Transport Proteins; Phenotype; Plasmodium falciparum; Potassium; Protozoan Proteins; Valinomycin; Verapamil | 2012 |