1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with caffeine in 50 studies
| Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone) | Studies (caffeine) | Trials (caffeine) | Recent Studies (post-2010) (caffeine) |
|---|---|---|---|---|---|
| 7,666 | 0 | 1,658 | 25,501 | 2,393 | 6,825 |
| Protein | Taxonomy | 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50) | caffeine (IC50) |
|---|---|---|---|
| Acetylcholinesterase | Homo sapiens (human) | 7.25 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (54.00) | 18.7374 |
| 1990's | 12 (24.00) | 18.2507 |
| 2000's | 3 (6.00) | 29.6817 |
| 2010's | 8 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishida, S; Kuwayama, H | 1 |
| Liwerant, IJ; Pereira da Silva, LH | 1 |
| Brenner, M; Geller, J | 1 |
| Cameron, AM; Coukell, MB | 1 |
| Bryant, PE | 1 |
| Okamoto, K; Yamada, Y; Yoshida, H | 1 |
| Fontana, DR; Luo, CS; Phillips, JC | 1 |
| Bodduluri, SR; Doody, JF; Dottin, RP; Haribabu, B; Moon, B; Mullings, S; Ortiz, BD; Pavlovic, J | 1 |
| Khosla, M; Robbins, SM; Spiegelman, GB; Weeks, G | 1 |
| Juliani, MH; Klein, C; Souza, GM | 1 |
| Barclay, SL; Riley, BB | 1 |
| Gonzalez, C; Klein, G; Satre, M | 1 |
| Condeelis, J; Hall, AL; Warren, V | 1 |
| Barclay, SL; Jensen, BR; Riley, BB | 1 |
| Firtel, RA; Mann, SK; Pinko, C | 3 |
| Chisholm, RL; Drummond, IA | 1 |
| Abe, T; Iijima, T; Maeda, Y | 1 |
| Atkinson, L; Kwong, L; Sobolewski, A; Weeks, G | 1 |
| Van Haastert, PJ | 3 |
| Durston, AJ; Weijer, CJ | 1 |
| Berlot, CH; Devreotes, PN; Spudich, JA | 2 |
| Armstrong, D; Firtel, RA; Gomer, RH; Leichtling, BH | 1 |
| Firtel, RA; Mann, SK | 1 |
| Kimmel, AR | 1 |
| Devreotes, P; Fontana, D; Klein, P; Sherring, J; Theibert, A | 1 |
| Hagmann, J | 1 |
| Deering, RA; Hoetzer, KE | 1 |
| Brachet, P; Dicou, E | 1 |
| Devreotes, PN; Theibert, A | 1 |
| Brenner, M; Thoms, SD | 1 |
| Aubry, L; Klein, G; Satre, M | 1 |
| Rutherford, CL; Selmin, O; Sucic, JF | 1 |
| Behrens, M; Fernández-Renart, M; Jiménez, B; Mazón, MJ; Schwandner, WR; Schwartz, A; Weijer, CJ | 1 |
| Davies, E; Kell, D; Olliff, C; Woodward, A; Wright, I | 1 |
| Chatterjee, S; Kumar, A | 1 |
| Amagai, A; Maeda, Y; Mayanagi, T | 1 |
| Alvarez-Curto, E; Schaap, P; Weening, KE | 1 |
| Aeckerle, S; Malchow, D | 1 |
| Baskar, R; Jaiswal, P; Soldati, T; Thewes, S | 1 |
| Kuwayama, H | 1 |
| Matsuoka, S; Nishikawa, M; Shibata, T; Ueda, M | 1 |
| Aiyar, P; Akkali, R; Baskar, R; Jaiswal, P; Singh, SP | 1 |
| Charest, PG; Haldeman, P; Rappel, WJ; Scavello, M; Tariqul Islam, AFM; Yue, H | 1 |
| Charest, PG; Daniel, D; Haldeman, P; Lotfi, P; Scavello, M; Tariqul Islam, AFM | 1 |
| Damstra-Oddy, J; Schaf, J; Williams, RSB | 1 |
1 review(s) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and caffeine
| Article | Year |
|---|---|
Dictyostelium discoideum as a pharmacological model system to study the mechanisms of medicinal drugs and natural products.
Topics: Animals; Anti-Infective Agents; Bacterial Infections; Biological Products; Bipolar Disorder; Caffeine; Dictyostelium; Drug Discovery; Epilepsy; Flavonoids; Humans; Models, Animal; Models, Biological; Neoplasms | 2019 |
49 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and caffeine
| Article | Year |
|---|---|
Biological soliton in multicellular movement.
Topics: Caffeine; Cell Adhesion; Cell Movement; Chemotaxis; Cyclic AMP; Dictyostelium; Genes, Protozoan; Hexanones; Mutation; Signal Transduction | 2013 |
Comparative mutagenic effects of ethyl methane-sulfonate, n-methyl-n'-nitro-n-nitrosoguanidine, ultraviolet radiation and caffeine on Dictyostelium discoideum.
Topics: Caffeine; Dictyostelium; Ethyl Methanesulfonate; Mesylates; Methylnitronitrosoguanidine; Mutagens; Myxomycetes; Nitrosoguanidines; Phenotype; Radiation Effects; Temperature; Ultraviolet Rays | 1975 |
The effect of 2,4-dinitrophenol on Dictyostelium discoideum oscillations.
Topics: Caffeine; Cyanides; Cyclic AMP; Dictyostelium; Dinitrophenols; Kinetics; Light; Myxomycetes; Scattering, Radiation | 1978 |
radE, a new radiation-sensitive locus in Dictyostelium discoideum.
Topics: Alleles; Caffeine; Cesium Radioisotopes; Dictyostelium; Genes, Recessive; Genetic Linkage; Mutagens; Mutation; Radiation Tolerance; Ultraviolet Rays | 1979 |
Effects of electrons and neutrons on the synthesis of RNA in resistant and sensitive strains of the slime-mould Dictyostelium discoideum and the modifying effect of caffeine.
Topics: Caffeine; Cell Survival; Dictyostelium; Dose-Response Relationship, Radiation; Electrons; Mutation; Myxomycetes; Neutrons; RNA; RNA, Messenger; RNA, Ribosomal | 1976 |
DC6, a novel type of Dictyostelium discoideum gene regulated by secreted factors but not by cAMP.
Topics: Adenosine; Animals; Blotting, Northern; Caffeine; Cell Differentiation; Cell Fractionation; Cloning, Molecular; Cyclic AMP; Dictyostelium; Gene Expression Regulation, Fungal; Genes, Fungal; RNA | 1991 |
Dictyostelium discoideum lipids modulate cell-cell cohesion and cyclic AMP signaling.
Topics: Adenylyl Cyclases; Caffeine; Cell Aggregation; Cell Communication; Cell Differentiation; Cell Membrane; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation; Membrane Lipids | 1991 |
Signal transduction pathways involved in the expression of the uridine diphosphoglucose pyrophosphorylase gene of Dictyostelium discoideum.
Topics: Animals; Base Sequence; Blotting, Northern; Caffeine; Dictyostelium; DNA, Fungal; Gene Expression Regulation, Fungal; Genetic Markers; Mice; Molecular Sequence Data; Regulatory Sequences, Nucleic Acid; Restriction Mapping; RNA, Antisense; Signal Transduction; Transformation, Genetic; UTP-Glucose-1-Phosphate Uridylyltransferase | 1991 |
Regulation of DdrasG gene expression during Dictyostelium development.
Topics: Amino Acids; Caffeine; Cyclic AMP; Cycloheximide; Dictyostelium; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, ras; ras Proteins; RNA, Fungal; RNA, Messenger | 1990 |
cAMP stimulation of Dictyostelium discoideum destabilizes the mRNA for 117 antigen.
Topics: Adenylyl Cyclase Inhibitors; Bucladesine; Caffeine; Cyclic AMP; Dictyostelium; DNA Probes; Down-Regulation; Enzyme Activation; Gene Expression Regulation; Mutation; Nucleic Acid Hybridization; Protein Biosynthesis; Protein Kinases; RNA, Messenger; Transcription, Genetic | 1990 |
Conditions that alter intracellular cAMP levels affect expression of the cAMP phosphodiesterase gene in Dictyostelium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Ammonium Chloride; Caffeine; Cell Membrane; Cyclic AMP; Cytoplasm; Dictyostelium; Gene Expression; Gene Expression Regulation, Fungal; Genes, Fungal; Kinetics; Models, Biological; Progesterone | 1990 |
Caffeine, an inhibitor of endocytosis in Dictyostelium discoideum amoebae.
Topics: Acid Phosphatase; Animals; Caffeine; Cell Differentiation; Dictyostelium; Endocytosis; Lanthanum; Mitosis; Phagocytosis; Pinocytosis | 1990 |
Transduction of the chemotactic signal to the actin cytoskeleton of Dictyostelium discoideum.
Topics: Actins; Adenylate Cyclase Toxin; Adenylyl Cyclases; Caffeine; Chemotaxis; Cytoskeleton; Dictyostelium; Folic Acid; Fungal Proteins; GTP-Binding Proteins; Mutation; Pertussis Toxin; Polymers; Receptors, Cyclic AMP; Signal Transduction; Virulence Factors, Bordetella | 1989 |
Conditions that elevate intracellular cyclic AMP levels promote spore formation in Dictyostelium.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Caffeine; Cell Survival; Cyclic AMP; Dictyostelium; Mutation; Spores, Fungal | 1989 |
cAMP regulation of early gene expression in signal transduction mutants of Dictyostelium.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Blotting, Northern; Caffeine; Cyclic AMP; Dictyostelium; Fungal Proteins; Gene Expression Regulation; Genes, Fungal; Mutation; Receptors, Cyclic AMP; RNA, Fungal; Time Factors | 1988 |
Regulation of Dictyostelium early gene expression in cAMP bypass mutants.
Topics: Blotting, Northern; Caffeine; Cyclic AMP; Dictyostelium; Gene Expression Regulation; Genes, Fungal; Mutation; RNA, Fungal | 1988 |
The effect of caffeine, adenosine, and buffer ionic composition on the induction of cell-surface cAMP binding during starvation of Dictyostelium discoideum.
Topics: Adenosine; Buffers; Caffeine; Cyclic AMP; Dictyostelium; Kinetics; Receptors, Cyclic AMP | 1988 |
Control of early gene expression in Dictyostelium.
Topics: Caffeine; Cyclic AMP; Dictyostelium; Gene Expression Regulation; Genes, Fungal; Mutation | 1988 |
Transient increase of the intracellular Ca2+ concentration during chemotactic signal transduction in Dictyostelium discoideum cells.
Topics: Caffeine; Calcium; Cyclic AMP; Dictyostelium; Signal Transduction | 1988 |
Stalk cell formation in monolayers from isolated prestalk and prespore cells of Dictyostelium discoideum: evidence for two populations of prestalk cells.
Topics: Caffeine; Cell Differentiation; Cells, Cultured; Cyclic AMP; Dictyostelium | 1988 |
The modulation of cell surface cAMP receptors from Dictyostelium discoideum by ammonium sulfate.
Topics: Ammonium Sulfate; Caffeine; Calcium; Calcium Chloride; Cyclic AMP; Dictyostelium; Half-Life; Kinetics; Receptors, Cyclic AMP | 1985 |
Influence of cyclic AMP and hydrolysis products on cell type regulation in Dictyostelium discoideum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acid Phosphatase; Adenine; Adenosine; Caffeine; Cell Differentiation; Cyclic AMP; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Isoenzymes; Spores, Fungal | 1985 |
Chemoattractant-elicited increases in myosin phosphorylation in Dictyostelium.
Topics: Adaptation, Physiological; Adenosine Triphosphate; Caffeine; Chemotaxis; Cyclic AMP; Dictyostelium; Dose-Response Relationship, Drug; Kinetics; Myosins; Phosphates; Phosphorylation | 1985 |
cAMP induction of prespore and prestalk gene expression in Dictyostelium is mediated by the cell-surface cAMP receptor.
Topics: Caffeine; Cell Differentiation; Cyclic AMP; Dictyostelium; Gene Expression Regulation; Receptors, Cyclic AMP; RNA, Messenger | 1986 |
Chemoattractant-elicited increases in Dictyostelium myosin phosphorylation are due to changes in myosin localization and increases in kinase activity.
Topics: Amino Acids; Caffeine; Calcium-Calmodulin-Dependent Protein Kinases; Chemotaxis; Chymotrypsin; Dictyostelium; Kinetics; Myosin-Light-Chain Phosphatase; Myosins; Phosphopeptides; Phosphoprotein Phosphatases; Phosphorylation; Phosphotransferases; Protozoan Proteins | 1987 |
Cyclic AMP regulation of early gene expression in Dictyostelium discoideum: mediation via the cell surface cyclic AMP receptor.
Topics: Amino Acid Sequence; Base Sequence; Caffeine; Cell Membrane; Cyclic AMP; Dictyostelium; Fungal Proteins; Gene Expression Regulation; Genes; Genes, Fungal; Kinetics; Receptors, Cyclic AMP; Sequence Homology, Nucleic Acid; Transcription, Genetic | 1987 |
Down-regulation of cell surface cyclic AMP receptors and desensitization of cyclic AMP-stimulated adenylate cyclase by cyclic AMP in Dictyostelium discoideum. Kinetics and concentration dependence.
Topics: Adenylyl Cyclases; Caffeine; Cell Membrane; Cyclic AMP; Dictyostelium; Dithiothreitol; Kinetics; Receptors, Cyclic AMP | 1987 |
Different molecular mechanisms for cAMP regulation of gene expression during Dictyostelium development.
Topics: Caffeine; Cyclic AMP; Dictyostelium; Gene Expression Regulation; Receptors, Cyclic AMP; RNA, Messenger | 1987 |
Transmembrane signaling in Dictyostelium.
Topics: Caffeine; Cell Communication; Cell Membrane; Chemotaxis; Cyclic AMP; Dictyostelium; Dithiothreitol; Methods | 1987 |
Developmentally regulated compartmentalization of adenylate cyclase in Dictyostelium discoideum.
Topics: Adenylyl Cyclases; Caffeine; Dictyostelium; Kinetics; Microscopy, Electron | 1988 |
Sensitization of rad mutants of Dictyostelium discoideum to ultraviolet light by postirradiation treatment with caffeine.
Topics: Caffeine; Dictyostelium; DNA Ligases; DNA Repair; Dose-Response Relationship, Radiation; Endonucleases; Radiation Tolerance; Radiation-Sensitizing Agents; Ultraviolet Rays | 1980 |
Interaction of the inhibitor of the 3',5' cyclic AMP phosphodiesterase of Dictyostelium discoideum with the Affi-Gel blue.
Topics: Adenosine Monophosphate; Anthracenes; Caffeine; Chromatography, Affinity; Cyclic AMP; Dictyostelium; Molecular Weight; Phosphodiesterase Inhibitors; Sodium Chloride; Triazines; Trifluoperazine | 1981 |
Cyclic 3', 5'-AMP relay in Dictyostelium discoideum: adaptation is independent of activation of adenylate cyclase.
Topics: Adaptation, Physiological; Adenylyl Cyclases; Caffeine; Cyclic AMP; Dictyostelium; Enzyme Activation; Kinetics | 1983 |
Caffeine blocks activation of cyclic AMP synthesis in Dictyostelium discoideum.
Topics: Adenylyl Cyclases; Caffeine; Calcimycin; Cell Survival; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Enzyme Activation | 1984 |
Endo-lysosomal acidification in Dictyostelium discoideum amoebae. Effects of two endocytosis inhibitors: caffeine and cycloheximide.
Topics: Animals; Caffeine; Cycloheximide; Dextrans; Dictyostelium; Fluorescein-5-isothiocyanate; Hydrogen-Ion Concentration; Kinetics; Lysosomes; Pinocytosis | 1993 |
Intracellular adenosine 3',5'-phosphate formation is essential for down-regulation of surface adenosine 3',5'-phosphate receptors in Dictyostelium.
Topics: Animals; Binding Sites; Caffeine; Cell Membrane Permeability; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; Down-Regulation; Enzyme Activation; Membrane Proteins; Mutation; Nucleotides, Cyclic; Receptors, Cyclic AMP; Thionucleotides | 1994 |
Regulation of the Dictyostelium glycogen phosphorylase 2 gene by cyclic AMP.
Topics: Animals; Base Sequence; Bucladesine; Caffeine; Cyclic AMP; Dictyostelium; Enzyme Induction; Fungal Proteins; Gene Expression Regulation, Fungal; Luciferases; Molecular Sequence Data; Phosphorylases; Promoter Regions, Genetic; Recombinant Fusion Proteins; RNA, Fungal; RNA, Messenger; Sequence Deletion; Signal Transduction | 1993 |
Chemotactic stimulation of aggregation-stage Dictyostelium cells induces rapid changes in energy metabolism, as measured by succinic thiokinase phosphorylation.
Topics: Animals; Caffeine; Calcium; Cell Aggregation; Cyclic AMP; Dictyostelium; Energy Metabolism; Histidine; Mitochondria; Phosphorylation; Succinate-CoA Ligases | 1993 |
A weak pulsed magnetic field affects adenine nucleotide oscillations, and related parameters in aggregating Dictyostelium discoideum amoebae.
Topics: Adenine Nucleotides; Animals; Caffeine; Cell Aggregation; Chromatography, High Pressure Liquid; Dictyostelium; Egtazic Acid; Electromagnetic Fields; Fourier Analysis; Light; Nonlinear Dynamics; Particle Size; Scattering, Radiation; Spectrometry, Fluorescence | 1999 |
Mitogenic stimulation in isoproterenol treated cells of dictyostelium discoideum.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Caffeine; Cell Division; Central Nervous System Stimulants; Dictyostelium; DNA; Dose-Response Relationship, Drug; Isoproterenol; Leucine; Mitogens; Phagocytosis; Propranolol; Thymidine; Time Factors | 2002 |
DNG1, a Dictyostelium homologue of tumor suppressor ING1 regulates differentiation of Dictyostelium cells.
Topics: Amino Acid Sequence; Animals; Caffeine; Cell Cycle Proteins; Cell Differentiation; Cell Line; Cell Proliferation; Culture Media, Conditioned; Cyclic AMP; Dictyostelium; DNA-Binding Proteins; Gene Expression Regulation, Developmental; Genes, Tumor Suppressor; Histones; Molecular Sequence Data; Mutation; Transcription Factors | 2005 |
Pharmacological profiling of the Dictyostelium adenylate cyclases ACA, ACB and ACG.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Animals; Caffeine; Cell Line; Dictyostelium; Gene Expression Profiling; Kinetics; Protozoan Proteins | 2007 |
Calcium regulates cAMP-induced potassium ion efflux in Dictyostelium discoideum.
Topics: Animals; Biological Transport; Caffeine; Calcium; Calcium Signaling; Cell Differentiation; Chemotaxis; Cyclic AMP; Dictyostelium; Egtazic Acid; Phosphodiesterase Inhibitors; Potassium | 1989 |
Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Deaminase; Caffeine; Cell Adhesion; Cell Adhesion Molecules; Cell Division; Cell Enlargement; Chemotactic Factors; Cyclic AMP; Cytoplasmic Streaming; Cytosol; Dictyostelium; Glucose; Protozoan Proteins; Signal Transduction | 2012 |
Arachidonic acid enhances caffeine-induced cell death via caspase-independent cell death.
Topics: Apoptosis; Arachidonic Acid; Caffeine; Caspases; Cell Survival; Cyclic AMP; Dictyostelium; Drug Resistance; Drug Synergism; Enzyme Activation; HeLa Cells; Humans; Phospholipases A2; Signal Transduction | 2012 |
Modeling the self-organized phosphatidylinositol lipid signaling system in chemotactic cells using quantitative image analysis.
Topics: Algorithms; Caffeine; Cell Membrane Structures; Cell Polarity; Chemotaxis; Computer Simulation; Dictyostelium; Diffusion; Models, Biological; Models, Statistical; Phosphatidylinositol Phosphates; Phospholipids; PTEN Phosphohydrolase; Second Messenger Systems; Single-Cell Analysis | 2012 |
Regulation of multiple tip formation by caffeine in cellular slime molds.
Topics: 1-Methyl-3-isobutylxanthine; Caffeine; Cell Transdifferentiation; Chemotactic Factors; Chemotaxis; Cyclic AMP; Cyclic Nucleotide Phosphodiesterases, Type 4; Dictyostelium; Dipeptides; Gene Expression; Kinetics; Lactams; Phosphodiesterase 4 Inhibitors; Protozoan Proteins | 2012 |
The cAMP-induced G protein subunits dissociation monitored in live Dictyostelium cells by BRET reveals two activation rates, a positive effect of caffeine and potential role of microtubules.
Topics: Bioluminescence Resonance Energy Transfer Techniques; Caffeine; Chemotactic Factors; Chemotaxis; Cyclic AMP; Dictyostelium; Heterotrimeric GTP-Binding Proteins; Microtubules; Signal Transduction | 2018 |
Caffeine inhibits PI3K and mTORC2 in Dictyostelium and differentially affects multiple other cAMP chemoattractant signaling effectors.
Topics: Caffeine; Chemotaxis; Cyclic AMP; Dictyostelium; Mechanistic Target of Rapamycin Complex 2; Phosphatidylinositol 3-Kinases; Protozoan Proteins; Second Messenger Systems | 2019 |