Page last updated: 2024-09-03

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and adenosine

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with adenosine in 29 studies

Compound Research Comparison

Studies
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Trials
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Recent Studies (post-2010)
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Studies
(adenosine)
Trials
(adenosine)
Recent Studies (post-2010) (adenosine)
7,66601,65832,5361,0758,930

Protein Interaction Comparison

ProteinTaxonomy1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50)adenosine (IC50)
high affinity choline transporter 1 isoform aHomo sapiens (human)0.3851
Sodium/nucleoside cotransporter 1Homo sapiens (human)5.5
Sodium/nucleoside cotransporter 2Homo sapiens (human)5.5
Adenosine receptor A3Homo sapiens (human)0.0011
Adenosine receptor A1Homo sapiens (human)0.0023
Equilibrative nucleoside transporter 1Homo sapiens (human)63
Solute carrier family 28 member 3Homo sapiens (human)3.3

Research

Studies (29)

TimeframeStudies, this research(%)All Research%
pre-199014 (48.28)18.7374
1990's10 (34.48)18.2507
2000's3 (10.34)29.6817
2010's2 (6.90)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gross, JD; Weeks, G1
Berks, M; Kay, RR1
Bloom, L; Kay, RR1
Rogers, PV; Rutherford, CL; Yin, Y1
Kubohara, Y; Maeda, M; Okamoto, K1
Escalante, R; Sastre, L1
Chia, WK1
Dottin, RP; Lodish, F; Weiner, AM1
Parish, RW1
Hesla, MA; Rossomando, EF1
Okamoto, K; Yamada, Y; Yoshida, H1
Schaap, P; Spek, W; van Drunen, K; van Eijk, R1
Chisholm, RL; Drummond, IA1
Howlett, A; Khachatrian, L; Klein, C1
Durston, AJ; Weijer, CJ1
Schaap, P; Wang, M1
Devreotes, PN; Theibert, A1
de Gunzburg, J; Hohman, R; Part, D; Veron, M1
Van Haastert, PJ1
Hodge, JL; Rossomando, EF1
Lewis, KE; O'Day, DH1
Davies, E; Olliff, C; Wright, I1
Hopper, NA; Schaap, P; Soede, RD; Williams, JG1
Brown, JM; Firtel, RA; McNally, JG; Sukumaran, S1
Brandt, R; Devreotes, PN; Kim, JY; Schaap, P; Verkerke-Van Wijk, I1
Angusti, A; Chen, Y; Deville-Bonne, D; Janin, J; Manfredini, S; Morera, S; Pasti, C; Solaroli, N; Véron, M1
Cejková, J; Hauser, MJ; Hilgardt, C; Sevcíková, H1
Baskar, R; Jaiswal, P; Soldati, T; Thewes, S1
Baskar, R; Hyde, GJ; Nassir, N1

Reviews

2 review(s) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and adenosine

ArticleYear
Potential morphogens involved in pattern formation during Dictyostelium differentiation.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1991, Volume: 69, Issue:9

    Topics: Adenosine; Ammonia; Animals; Cell Differentiation; Cyclic AMP; Dictyostelium; Hexanones; Molecular Weight; Morphogenesis; Spores, Fungal

1991
The search for morphogens in Dictyostelium.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 1988, Volume: 9, Issue:6

    Topics: Adenosine; Ammonia; Cyclic AMP; Dictyostelium; Hexanones; Morphogenesis; Pentanones

1988

Other Studies

27 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and adenosine

ArticleYear
Combinatorial control of cell differentiation by cAMP and DIF-1 during development of Dictyostelium discoideum.
    Development (Cambridge, England), 1990, Volume: 110, Issue:3

    Topics: Adenosine; Ammonia; Cell Differentiation; Cyclic AMP; Dictyostelium; Genetic Markers; Hexanones; RNA, Messenger

1990
Dual regulation of the glycogen phosphorylase 2 gene Dictyostelium discoideum: the effects of DIF-1, cAMP, NH3 and adenosine.
    Development (Cambridge, England), 1994, Volume: 120, Issue:5

    Topics: Adenosine; Ammonia; Animals; Base Sequence; Cell Differentiation; Cloning, Molecular; Cyclic AMP; Dictyostelium; Embryonic Induction; Gene Expression; Gene Expression Regulation, Fungal; Genes, Fungal; Hexanones; Models, Genetic; Molecular Sequence Data; Phosphorylases

1994
Analysis of the maturation process of prestalk cells in Dictyostelium discoideum.
    Experimental cell research, 1993, Volume: 207, Issue:1

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Calcium; Cell Differentiation; Cells, Cultured; Dictyostelium; Dimethadione; Hexanones; Pentanones; Protein Kinases

1993
cAMP and DIF-1 repress the expression of the Dictyostelium MADS-box gene srfA at early stages of development.
    Biochemical and biophysical research communications, 2001, Jul-20, Volume: 285, Issue:3

    Topics: Adenosine; Ammonia; Animals; Bacterial Proteins; Cell Aggregation; Cell Differentiation; Chemokine CXCL12; Chemokines, CXC; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; Enzyme Inhibitors; Gene Expression Regulation, Developmental; Hexanones; Intercellular Signaling Peptides and Proteins; Peptide Synthases; Peptides; Promoter Regions, Genetic; Protein Serine-Threonine Kinases; Protein Synthesis Inhibitors; Protein-Tyrosine Kinases; Proteins; Protozoan Proteins; RNA, Messenger; Transcription Factors

2001
Induction of stalk cell differentiation by cyclic-AMP in a susceptible variant of Dictyostelium discoideum.
    Developmental biology, 1975, Volume: 44, Issue:2

    Topics: Adenosine; Adenosine Monophosphate; Amoeba; Cell Aggregation; Cell Differentiation; Cells, Cultured; Chemotaxis; Clone Cells; Cyclic AMP; Cyclic GMP; Dialysis; Dictyostelium; Escherichia coli; Genetic Variation; Growth; Myxomycetes; Phosphoric Diester Hydrolases; Spores, Fungal

1975
5' terminal nucleotide sequences of the messenger RNA's of Dictyostelium discoideum.
    Cell, 1976, Volume: 8, Issue:2

    Topics: Adenosine; Alkaline Phosphatase; Base Sequence; Dictyostelium; Electrophoresis; Guanine Nucleotides; Myxomycetes; Oligoribonucleotides; Phosphoric Diester Hydrolases; Ribonucleases; RNA, Messenger

1976
Inhibition of Dictyostelium discoideum beta-glucosidase by purines.
    Journal of bacteriology, 1977, Volume: 129, Issue:3

    Topics: Adenine; Adenosine; Dictyostelium; Glucose; Glucosidases; Guanosine; Hypoxanthines; Inosine; Kinetics; Myxomycetes; Purines

1977
Time-dependent changes in Dictyostelium discoideum adenylate cyclase activity upon incubation with ATP.
    The Journal of biological chemistry, 1976, Nov-10, Volume: 251, Issue:21

    Topics: Adenosine; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Cyclases; Dictyostelium; Enzyme Activation; Kinetics; Myxomycetes; Structure-Activity Relationship; Time Factors

1976
DC6, a novel type of Dictyostelium discoideum gene regulated by secreted factors but not by cAMP.
    Differentiation; research in biological diversity, 1991, Volume: 46, Issue:3

    Topics: Adenosine; Animals; Blotting, Northern; Caffeine; Cell Differentiation; Cell Fractionation; Cloning, Molecular; Cyclic AMP; Dictyostelium; Gene Expression Regulation, Fungal; Genes, Fungal; RNA

1991
Opposite effects of adenosine on two types of cAMP-induced gene expression in Dictyostelium indicate the involvement of at least two different intracellular pathways for the transduction of cAMP signals.
    FEBS letters, 1988, Feb-15, Volume: 228, Issue:2

    Topics: Adenosine; Cyclic AMP; Dictyostelium; Gene Expression Regulation; Genes, Fungal; RNA, Fungal; RNA, Messenger; Spores, Fungal

1988
The effect of caffeine, adenosine, and buffer ionic composition on the induction of cell-surface cAMP binding during starvation of Dictyostelium discoideum.
    Developmental genetics, 1988, Volume: 9, Issue:4-5

    Topics: Adenosine; Buffers; Caffeine; Cyclic AMP; Dictyostelium; Kinetics; Receptors, Cyclic AMP

1988
Regulation of Dictyostelium discoideum adenylate cyclase by manganese and adenosine analogs.
    Biochimica et biophysica acta, 1987, Feb-18, Volume: 927, Issue:2

    Topics: Adenosine; Adenylyl Cyclases; Allosteric Regulation; Chlorides; Cyclic AMP; Dictyostelium; Fungal Proteins; Guanosine Triphosphate; Guanylate Cyclase; Magnesium; Magnesium Chloride; Manganese; Manganese Compounds; Membrane Proteins; Temperature

1987
Influence of cyclic AMP and hydrolysis products on cell type regulation in Dictyostelium discoideum.
    Journal of embryology and experimental morphology, 1985, Volume: 86

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Acid Phosphatase; Adenine; Adenosine; Caffeine; Cell Differentiation; Cyclic AMP; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Isoenzymes; Spores, Fungal

1985
Interactions between adenosine and oscillatory cAMP signaling regulate size and pattern in Dictyostelium.
    Cell, 1986, Apr-11, Volume: 45, Issue:1

    Topics: Adenosine; Cell Aggregation; Cell Differentiation; Cyclic AMP; Dictyostelium; Periodicity

1986
Adenosine and its derivatives inhibit the cAMP signaling response in Dictyostelium discoideum.
    Developmental biology, 1984, Volume: 106, Issue:1

    Topics: 2-Chloroadenosine; Adenosine; Cyclic AMP; Dictyostelium; Kinetics

1984
Evidence that a cAMP binding protein from Dictyostelium discoideum carries S-adenosyl-L-homocysteine hydrolase activity.
    Biochimie, 1983, Volume: 65, Issue:1

    Topics: Adenosine; Adenosylhomocysteinase; Carrier Proteins; Chromatography, Ion Exchange; Cyclic AMP; Cyclic AMP Receptor Protein; Dictyostelium; Hydrolases; Molecular Weight

1983
Binding of cAMP and adenosine derivatives to Dictyostelium discoideum cells. Relationships of binding, chemotactic, and antagonistic activities.
    The Journal of biological chemistry, 1983, Aug-25, Volume: 258, Issue:16

    Topics: Adenosine; Binding, Competitive; Chemotaxis; Cyclic AMP; Dictyostelium; Receptors, Cell Surface; Receptors, Cyclic AMP; Receptors, Purinergic

1983
Degradation of ATP by membrane-bound enzymatic activities in Dictyostelium discoideum monitored by high-pressure liquid chromatography.
    Analytical biochemistry, 1980, Volume: 102, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenosine Triphosphate; Cell Membrane; Chromatography, High Pressure Liquid; Dictyostelium

1980
Cannibalistic sexual phagocytosis in Dictyostelium discoideum is modulated by adenosine via an A2-like receptor.
    Cellular signalling, 1994, Volume: 6, Issue:2

    Topics: Adenosine; Adenosine Deaminase; Animals; Bucladesine; Chromatography, High Pressure Liquid; Cyclic AMP; Dictyostelium; Phagocytosis; Receptors, Purinergic P1; Signal Transduction

1994
Pulsed magnetic fields affect oscillations of the adenylate cyclase enzyme system in Dictyostelium discoideum, athermally.
    Biochemical Society transactions, 1994, Volume: 22, Issue:1

    Topics: Adenine; Adenine Nucleotides; Adenosine; Adenylyl Cyclases; Animals; Dictyostelium; Kinetics; Magnetics; Spores, Fungal; Time Factors

1994
Extracellular cAMP depletion triggers stalk gene expression in Dictyostelium: disparities in developmental timing and dose dependency indicate that prespore induction and stalk repression by cAMP are mediated by separate signaling pathways.
    Developmental biology, 1996, Jul-10, Volume: 177, Issue:1

    Topics: Adenosine; Animals; Cell Differentiation; Cell Line; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; Dose-Response Relationship, Drug; Extracellular Matrix Proteins; Gene Expression Regulation, Developmental; Protozoan Proteins; Second Messenger Systems; Signal Transduction; Spores; Transcriptional Activation

1996
lagC-null and gbf-null cells define key steps in the morphogenesis of Dictyostelium mounds.
    Developmental biology, 1998, Aug-01, Volume: 200, Issue:1

    Topics: Adenosine; Animals; Cell Movement; Cyclic AMP; Dictyostelium; DNA-Binding Proteins; G-Box Binding Factors; Genes, Fungal; Genes, Protozoan; Membrane Proteins; Models, Genetic; Morphogenesis; Mutation; Signal Transduction; Transcription Factors

1998
Functional promiscuity of gene regulation by serpentine receptors in Dictyostelium discoideum.
    Molecular and cellular biology, 1998, Volume: 18, Issue:10

    Topics: Adenosine; Animals; Cell Line; Cyclic AMP; Dictyostelium; Extracellular Matrix Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Lymphokines; Protozoan Proteins; Receptors, Cyclic AMP; Transcriptional Activation

1998
Adenosine phosphonoacetic acid is slowly metabolized by NDP kinase.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2005, Volume: 1, Issue:6

    Topics: Adenosine; Adenosine Diphosphate; Animals; Binding Sites; Catalysis; Crystallization; Dictyostelium; Enzyme Inhibitors; Humans; Kinetics; Models, Molecular; Molecular Structure; Nucleoside-Diphosphate Kinase; Phosphonoacetic Acid; Structure-Activity Relationship; X-Ray Diffraction

2005
Streamless aggregation of Dictyostelium in the presence of isopropylidenadenosin.
    Biophysical chemistry, 2008, Volume: 132, Issue:1

    Topics: Adenosine; Adenylyl Cyclase Inhibitors; Animals; Cell Aggregation; Cyclic AMP; Dictyostelium

2008
Regulation of aggregate size and pattern by adenosine and caffeine in cellular slime molds.
    BMC developmental biology, 2012, Jan-23, Volume: 12

    Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Adenosine Deaminase; Caffeine; Cell Adhesion; Cell Adhesion Molecules; Cell Division; Cell Enlargement; Chemotactic Factors; Cyclic AMP; Cytoplasmic Streaming; Cytosol; Dictyostelium; Glucose; Protozoan Proteins; Signal Transduction

2012
A telomerase with novel non-canonical roles: TERT controls cellular aggregation and tissue size in Dictyostelium.
    PLoS genetics, 2019, Volume: 15, Issue:6

    Topics: Adenosine; Animals; Cell Aggregation; Chemotaxis; Cyclic AMP; Dictyostelium; Enzyme Inhibitors; Gene Knockout Techniques; Glucose; Morphogenesis; Signal Transduction; Telomerase

2019