Page last updated: 2024-09-03

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and adenosine diphosphate

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with adenosine diphosphate in 80 studies

Compound Research Comparison

Studies
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Trials
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Recent Studies (post-2010)
(1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)
Studies
(adenosine diphosphate)
Trials
(adenosine diphosphate)
Recent Studies (post-2010) (adenosine diphosphate)
7,66601,65823,9894983,114

Protein Interaction Comparison

ProteinTaxonomy1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone (IC50)adenosine diphosphate (IC50)
Chain A, Kinesin-like protein KIF11Homo sapiens (human)0.45
Heat shock 70 kDa protein 1A Homo sapiens (human)0.5
Sensor protein kinase WalKStaphylococcus aureus7.189

Research

Studies (80)

TimeframeStudies, this research(%)All Research%
pre-19904 (5.00)18.7374
1990's27 (33.75)18.2507
2000's37 (46.25)29.6817
2010's10 (12.50)24.3611
2020's2 (2.50)2.80

Authors

AuthorsStudies
Beattie, DS; Kobilinsky, L; Weinstein, BI1
Konijn, TM; Mato, JM1
Pamula, F; Wheldrake, JF2
Snaar-Jagalska, BE; Van Haastert, PJ1
Van Haastert, PJ1
DeToma, FJ; DiDomenico, L; Komuniecki, PR; Lawrence, MH1
Fisher, AJ; Holden, HM; Rayment, I; Smith, CA; Smith, R; Sutoh, K; Thoden, JB1
Rayment, I; Smith, CA2
Fisher, AJ; Holden, HM; Rayment, I; Smith, CA; Smith, R; Sutoh, K; Thoden, J1
Howlett, AC; Klein, C; Tao, Y1
Briozzo, P; Dumas, C; Janin, J; Lascu, I; LeBras, G; Moréra, S; Véron, M1
Geeves, MA; Manstein, DJ; Woodward, SK1
Cervoni, L; Erent, M; Giartosio, A; Janin, J; Konrad, M; Lascu, I; Moréra, S1
Condeelis, JS; Eddy, RJ; Han, J; Sauterer, RA1
Geeves, MA; Kurzawa, SE; Manstein, DJ1
Holmes, KC1
Cherfils, J; Janin, J; Moréra, S; Xu, YW1
Bauer, CB; Gulick, AM; Rayment, I; Thoden, JB1
Birney, M; Klein, C; Um, H1
Bobkov, AA; Reisler, E; Sutoh, K1
Ohkura, R; Sasaki, N; Shimada, T; Sutoh, K1
Bagshaw, CR; Bauer, CB; Kuhlman, PA; Rayment, I1
Geeves, MA; Levitsky, DI; Manstein, DJ; Ponomarev, MA; Shnyrov, VL1
Biondi, RM; Passeron, E; Passeron, S; Schneider, B1
Friedman, AL; Geeves, MA; Manstein, DJ; Spudich, JA1
Cohen, C; Dominguez, R; Freyzon, Y; Trybus, KM1
Fujita-Becker, S; Furch, M; Geeves, MA; Holmes, KC; Manstein, DJ1
Knetsch, ML; Manstein, DJ; Uyeda, TQ1
Gillespie, PG; Gillespie, SK; Mercer, JA; Shah, K; Shokat, KM1
Bauer, CB; Gulick, AM; Pate, E; Rayment, I; Thoden, JB; Yount, RG1
Furch, M; Levitsky, DI; Manstein, DJ; Ponomarev, MA1
Brown, F; Cheung, HC; Milligan, RA; Rosenfeld, SS; Sweeney, HL; Wells, A; Whitaker, M; Xing, J1
Gryczynski, Z; Lakowicz, JR; Shih, WM; Spudich, JA1
Bagshaw, CR; Málnási-Csizmadia, A; Woolley, RJ1
Suzuki, Y1
Murphy, CT; Rock, RS; Spudich, JA1
Bagshaw, CR; Botchway, SW; Kovacs, M; Malnasi-Csizmadia, A; Woolley, RJ1
Cervoni, L; Giartosio, A; Gonin, P; Janin, J; Lascu, I; Merouani, M; Morr, M; Xu, Y1
Urbanke, C; Wray, J1
Kaseda, K; Patterson, B; Tokuraku, K; Uyeda, TQ; Webb, MR1
Bobkov, A; Muhlrad, A; Reisler, E; Reynoso, JR1
Helms, V; Hutter, MC1
Ohkura, R; Sasaki, N; Sutoh, K1
Ballweber, E; Kiessling, P; Mannherz, HG; Manstein, D1
Ito, K; Sutoh, K; Suzuki, Y; Uyeda, TQ; Yamamoto, K1
Hachikubo, Y; Ito, K; Yamamoto, K1
Bagshaw, CR; Conibear, PB; Floyd, DN; Kovács, M; Málnási-Csizmadia, A; Wakelin, S; Woolley, RJ1
Becker, A; Eschenburg, S; Kull, FJ; Manstein, DJ; Reubold, TF1
Lawson, JD; Pate, E; Rayment, I; Yount, RG1
Clark, RJ; Dürrwang, U; Erent, M; Fujita-Becker, S; Geeves, MA; Manstein, DJ1
Bagshaw, CR; Conibear, PB; Málnási-Csizmadia, A1
Korn, ED; Kovács, M; Liu, X; Shu, S1
Berger, CL; Chrin, LR; Gaffney, DP; Robertson, CI1
Dürrwang, U; Erent, M; Fujita-Becker, S; Geeves, MA; Kull, FJ; Manstein, DJ; Tsiavaliaris, G1
Angusti, A; Chen, Y; Deville-Bonne, D; Janin, J; Manfredini, S; Morera, S; Pasti, C; Solaroli, N; Véron, M1
Fischer, S; Koppole, S; Smith, JC1
Chaen, S; Hanamoto, D; Iwai, S1
Fujita-Becker, S; Manstein, DJ; Ohkura, R; Shimada, T; Sutoh, K; Tsiavaliaris, G1
Bagshaw, CR; Geeves, MA; Gyimesi, M; Kintses, B; Málnási-Csizmadia, A; Pearson, DS; Zeng, W1
Morales, MF; Onishi, H1
Jahn, W1
Gyimesi, M; Kellermayer, MS; Málnási-Csizmadia, A; Tsaturyan, AK1
Bagshaw, CR; Bodor, A; Fischer, S; Gyimesi, M; Kintses, B; Málnási-Csizmadia, A; Perczel, A1
Cao, L; Fountain, SJ; North, RA; Young, MT1
Ennion, SJ; Fisher, PR; Ludlow, MJ; Traynor, D1
Chizhov, I; Hartmann, FK; Keller, H; Manstein, DJ; Rump, A; Taft, MH; Tsiavaliaris, G1
Billington, N; Gyimesi, M; Kintses, B; Knight, PJ; Kovács, M; Málnási-Csizmadia, A; Takács, B1
Berger, CL; Cooke, R; Dunn, AR; Eldred, CC; Franks-Skiba, K; Málnási-Csizmadia, A; Naber, N; Pate, E; Purcell, TJ; Spudich, JA; Swank, DM1
Kon, T; Kurisu, G; Sutoh, K1
Adamek, N; Bauer, S; Fedorov, R; Fujita-Becker, S; Geeves, MA; Manstein, DJ; Preller, M1
Borer, C; Couto, CA; Kiely, R; Lakin, ND; Pears, CJ; Wang, HY1
Imamula, K; Kon, T; Kurisu, G; Oyama, T; Shima, T; Shimo-Kon, R; Sutoh, K1
Guhathakurta, P; Muretta, JM; Prochniewicz, E; Thomas, DD; Titus, MA1
Burgess, SA; Edwards, TA; Knight, PJ; Kon, T; Malkova, B; Numata, N; Ohkura, R; Oiwa, K; Roberts, AJ; Sakakibara, H; Sutoh, K; Walker, ML1
Chizhov, I; Hartmann, FK; Hundt, N; Tsiavaliaris, G1
Gomibuchi, Y; Uyeda, TQ; Wakabayashi, T1
Childers, MC; Daggett, V; Geeves, M; Regnier, M1
Ando, T; Behjat, AB; Fukuma, T; Hayakawa, Y; Hirose, K; Imai, T; Kodera, N; Nakano, K; Ngo, KX; Numata, O; Takaine, M; Tokuraku, K; Umeda, K; Uyeda, TQ; Yamada, MD; Yurtsever, A1

Reviews

3 review(s) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and adenosine diphosphate

ArticleYear
The swinging lever-arm hypothesis of muscle contraction.
    Current biology : CB, 1997, Feb-01, Volume: 7, Issue:2

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dictyostelium; Models, Biological; Models, Molecular; Models, Structural; Muscle Contraction; Muscle, Skeletal; Myosins; Protein Structure, Secondary; Vanadates

1997
Engineering Dictyostelium discoideum myosin II for the introduction of site-specific fluorescence probes.
    Journal of muscle research and cell motility, 2002, Volume: 23, Issue:7-8

    Topics: Adenosine Diphosphate; Animals; Dictyostelium; Fluorescent Dyes; Genes, Reporter; Green Fluorescent Proteins; Kinetics; Luminescent Proteins; Myosin Type II; Protein Engineering; Protozoan Proteins; Tryptophan

2002
The role of ADP-ribosylation in regulating DNA double-strand break repair.
    Cell cycle (Georgetown, Tex.), 2012, Jan-01, Volume: 11, Issue:1

    Topics: Adenosine Diphosphate; Dictyostelium; DNA Breaks, Double-Stranded; DNA Repair; Genomic Instability; Humans; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Poly(ADP-ribose) Polymerases

2012

Other Studies

77 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and adenosine diphosphate

ArticleYear
The induction of filopodia in the cellular slime mold Dictyostelium discoideum by cyclic adenosine monophosphate: mechanism of aggregation.
    Developmental biology, 1976, Volume: 48, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Azides; Cell Aggregation; Concanavalin A; Cyclic AMP; Cyclic GMP; Dictyostelium; Dinitrophenols; Myxomycetes; Pseudopodia

1976
The activation of cell aggregation by phosphorylation in Dictyostelium discoideum.
    Experimental cell research, 1976, Volume: 99, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Cell Aggregation; Chemotaxis; Dictyostelium; Myxomycetes; Phosphates; Protein Kinases

1976
Purification and properties of the NADP-dependent glutamate dehydrogenase from Dictyostelium discoideum.
    Molecular and cellular biochemistry, 1991, Jun-26, Volume: 105, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Animals; Cyclic AMP; Dictyostelium; Ethylmaleimide; Glutamate Dehydrogenase; Glutamate Dehydrogenase (NADP+); Guanosine Triphosphate; Hydrogen-Ion Concentration; Hydroxymercuribenzoates; Molecular Weight; Morphogenesis

1991
The NAD-dependent glutamate dehydrogenase from Dictyostelium discoideum: purification and properties.
    Archives of biochemistry and biophysics, 1991, Volume: 291, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Monophosphate; Ammonium Chloride; Animals; Dictyostelium; Enzyme Activation; Glutamate Dehydrogenase; Hydrogen-Ion Concentration; Ketoglutaric Acids; Kinetics; NAD

1991
Pertussis toxin inhibits cAMP-induced desensitization of adenylate cyclase in Dictyostelium discoideum.
    Molecular and cellular biochemistry, 1990, Feb-09, Volume: 92, Issue:2

    Topics: Adenosine Diphosphate; Adenylate Cyclase Toxin; Adenylyl Cyclases; Cell Membrane; Chemotaxis; Cyclic AMP; Cyclic GMP; Dictyostelium; Down-Regulation; Enzyme Activation; Pertussis Toxin; Phosphorylation; Receptors, Cyclic AMP; Virulence Factors, Bordetella

1990
Guanine nucleotides modulate cell surface cAMP-binding sites in membranes from Dictyostelium discoideum.
    Biochemical and biophysical research communications, 1984, Oct-30, Volume: 124, Issue:2

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Cell Membrane; Cyclic AMP; Dictyostelium; Guanosine Triphosphate; Guanylyl Imidodiphosphate; Kinetics; Receptors, Cyclic AMP; Structure-Activity Relationship

1984
ADP phosphorylation and glutamate oxidation in mitochondria isolated from Dictyostelium discoideum amoebae.
    Biochemical and biophysical research communications, 1980, Oct-16, Volume: 96, Issue:3

    Topics: Adenosine Diphosphate; Dictyostelium; Glutamates; Mitochondria; Oxidation-Reduction; Oxygen Consumption; Phosphorylation

1980
X-ray structures of the myosin motor domain of Dictyostelium discoideum complexed with MgADP.BeFx and MgADP.AlF4-.
    Biochemistry, 1995, Jul-18, Volume: 34, Issue:28

    Topics: Adenine; Adenosine Diphosphate; Aluminum Compounds; Amino Acid Sequence; Animals; Beryllium; Binding Sites; Crystallography, X-Ray; Dictyostelium; Energy Metabolism; Fluorides; Hydrolysis; Models, Molecular; Molecular Sequence Data; Molecular Structure; Myosins; Phosphates; Protein Conformation; Protein Structure, Tertiary; Ribose

1995
X-ray structure of the magnesium(II)-pyrophosphate complex of the truncated head of Dictyostelium discoideum myosin to 2.7 A resolution.
    Biochemistry, 1995, Jul-18, Volume: 34, Issue:28

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Beryllium; Binding Sites; Crystallography, X-Ray; Dictyostelium; Diphosphates; Fluorides; Magnesium Compounds; Models, Molecular; Molecular Sequence Data; Molecular Structure; Myosins; Protein Conformation; Protein Folding

1995
Structural studies of myosin:nucleotide complexes: a revised model for the molecular basis of muscle contraction.
    Biophysical journal, 1995, Volume: 68, Issue:4 Suppl

    Topics: Adenosine Diphosphate; Aluminum Compounds; Animals; Beryllium; Binding Sites; Biophysical Phenomena; Biophysics; Dictyostelium; Fluorides; Models, Biological; Models, Molecular; Molecular Structure; Muscle Contraction; Myosin Subfragments; Nucleotides; Protein Conformation

1995
Endogenous ADP-ribosylation of glyceraldehyde-3-phosphate dehydrogenase that is not regulated by nitric oxide in Dictyostelium discoideum.
    Cellular signalling, 1993, Volume: 5, Issue:6

    Topics: Adenosine Diphosphate; Animals; Cyclic GMP; Cytosol; Dictyostelium; Genetic Linkage; Glyceraldehyde-3-Phosphate Dehydrogenases; Guanylate Cyclase; Nitric Oxide; Peptide Fragments; Peptide Mapping

1993
Adenosine 5'-diphosphate binding and the active site of nucleoside diphosphate kinase.
    Biochemistry, 1994, Jan-18, Volume: 33, Issue:2

    Topics: Adenosine Diphosphate; Animals; Binding Sites; Crystallization; Crystallography, X-Ray; Dictyostelium; Escherichia coli; Histidine; Macromolecular Substances; Magnesium; Models, Molecular; Molecular Structure; Nucleoside-Diphosphate Kinase; Phosphorylation; Protein Structure, Secondary; Recombinant Proteins

1994
Kinetic characterization of the catalytic domain of Dictyostelium discoideum myosin.
    Biochemistry, 1995, Dec-12, Volume: 34, Issue:49

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Base Sequence; Binding Sites; Binding, Competitive; Catalysis; Cloning, Molecular; Dictyostelium; DNA Primers; Histidine; Kinetics; Molecular Sequence Data; Mutagenesis, Site-Directed; Myosins; Open Reading Frames; Polymerase Chain Reaction; Recombinant Proteins; Restriction Mapping; Sequence Tagged Sites

1995
X-ray structure of the magnesium(II).ADP.vanadate complex of the Dictyostelium discoideum myosin motor domain to 1.9 A resolution.
    Biochemistry, 1996, Apr-30, Volume: 35, Issue:17

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Binding Sites; Crystallography, X-Ray; Dictyostelium; Hydrogen Bonding; Magnesium; Models, Molecular; Molecular Sequence Data; Myosin Subfragments; Protein Conformation; Protein Structure, Tertiary; Vanadates

1996
Thermal stability of hexameric and tetrameric nucleoside diphosphate kinases. Effect of subunit interaction.
    The Journal of biological chemistry, 1996, Jul-26, Volume: 271, Issue:30

    Topics: Adenosine Diphosphate; Animals; Crystallography, X-Ray; Dictyostelium; Enzyme Stability; Escherichia coli; Hot Temperature; Kinetics; Molecular Sequence Data; Nephelometry and Turbidimetry; Nucleoside-Diphosphate Kinase; Protein Conformation

1996
A major agonist-regulated capping activity in Dictyostelium is due to the capping protein, cap32/34.
    Biochimica et biophysica acta, 1996, Dec-12, Volume: 1314, Issue:3

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Carrier Proteins; Dictyostelium; Fungal Proteins; HSC70 Heat-Shock Proteins; HSP70 Heat-Shock Proteins; Kinetics; Microfilament Proteins; Molecular Weight; Protein Binding; Protozoan Proteins

1996
Dictyostelium discoideum myosin II: characterization of functional myosin motor fragments.
    Biochemistry, 1997, Jan-14, Volume: 36, Issue:2

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Chickens; Dictyostelium; Kinetics; Molecular Sequence Data; Muscle, Skeletal; Myosin Subfragments; Myosins; Peptide Fragments; Recombinant Proteins

1997
AlF3 mimics the transition state of protein phosphorylation in the crystal structure of nucleoside diphosphate kinase and MgADP.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Apr-15, Volume: 94, Issue:8

    Topics: Adenosine Diphosphate; Aluminum Compounds; Animals; Crystallization; Dictyostelium; Nucleoside-Diphosphate Kinase; Phosphorylation; Protein Conformation

1997
X-ray structures of the MgADP, MgATPgammaS, and MgAMPPNP complexes of the Dictyostelium discoideum myosin motor domain.
    Biochemistry, 1997, Sep-30, Volume: 36, Issue:39

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Chickens; Dictyostelium; Magnesium; Models, Molecular; Molecular Sequence Data; Myosins; X-Ray Diffraction

1997
Multiple levels of regulation of Escherichia coli succinyl-CoA synthetase.
    Archives of biochemistry and biophysics, 1997, Nov-01, Volume: 347, Issue:1

    Topics: Adenosine Diphosphate; Allosteric Site; Animals; Bacterial Proteins; Binding Sites; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Escherichia coli; Escherichia coli Proteins; GTP Phosphohydrolases; GTP-Binding Proteins; Guanosine Diphosphate; Phosphorylation; Protein Denaturation; RNA-Binding Proteins; Succinate-CoA Ligases; Temperature

1997
Nucleotide and actin binding properties of the isolated motor domain from Dictyostelium discoideum myosin.
    Journal of muscle research and cell motility, 1997, Volume: 18, Issue:5

    Topics: Acrylamide; Acrylamides; Actins; Adenosine Diphosphate; Animals; Binding Sites; Ca(2+) Mg(2+)-ATPase; Dictyostelium; Kinetics; Myosin Subfragments; Myosins

1997
Alanine scanning mutagenesis of the switch I region in the ATPase site of Dictyostelium discoideum myosin II.
    Biochemistry, 1997, Nov-18, Volume: 36, Issue:46

    Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Alanine; Animals; Binding Sites; Deafness; Dictyostelium; DNA Mutational Analysis; Humans; Hydrolysis; Locomotion; Motion; Mutagenesis; Myosins; ortho-Aminobenzoates; Recombinant Proteins

1997
X-ray crystal structure and solution fluorescence characterization of Mg.2'(3')-O-(N-methylanthraniloyl) nucleotides bound to the Dictyostelium discoideum myosin motor domain.
    Journal of molecular biology, 1997, Dec-05, Volume: 274, Issue:3

    Topics: Acrylamide; Acrylamides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Beryllium; Binding Sites; Crystallography, X-Ray; Dictyostelium; Fluorescence; Fluorides; Magnesium; Models, Molecular; Muscle, Skeletal; Myosins; Nucleic Acid Conformation; ortho-Aminobenzoates; Protein Conformation; Rabbits; Solutions

1997
Differential scanning calorimetric study of the thermal unfolding of the motor domain fragments of Dictyostelium discoideum myosin II.
    European journal of biochemistry, 1998, Jan-15, Volume: 251, Issue:1-2

    Topics: Actins; Adenosine Diphosphate; Animals; Calorimetry, Differential Scanning; Dictyostelium; Myosin Subfragments; Myosins; Protein Folding

1998
Role of Mg2+ in nucleoside diphosphate kinase autophosphorylation.
    Archives of biochemistry and biophysics, 1998, May-01, Volume: 353, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Candida albicans; Dictyostelium; Edetic Acid; Kinetics; Magnesium; Magnesium Chloride; Models, Molecular; Nucleoside-Diphosphate Kinase; Phosphorylation; Protein Conformation; Recombinant Proteins; Spectrometry, Fluorescence

1998
Kinetic characterization of myosin head fragments with long-lived myosin.ATP states.
    Biochemistry, 1998, Jul-07, Volume: 37, Issue:27

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dictyostelium; Glutamic Acid; Hydrolysis; Kinetics; Mutagenesis, Site-Directed; Myosins; ortho-Aminobenzoates; Protein Binding; Spectrometry, Fluorescence; Valine

1998
Crystal structure of a vertebrate smooth muscle myosin motor domain and its complex with the essential light chain: visualization of the pre-power stroke state.
    Cell, 1998, Sep-04, Volume: 94, Issue:5

    Topics: Actins; Adenosine Diphosphate; Amino Acid Sequence; Animals; Binding Sites; Chickens; Crystallography, X-Ray; Dictyostelium; Macromolecular Substances; Models, Molecular; Molecular Sequence Data; Muscle, Smooth; Myosin Light Chains; Myosin Subfragments; Protein Conformation; Protein Structure, Tertiary

1998
Role of the salt-bridge between switch-1 and switch-2 of Dictyostelium myosin.
    Journal of molecular biology, 1999, Jul-16, Volume: 290, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dictyostelium; Fluorescent Dyes; Hydrolysis; Kinetics; Models, Molecular; Myosins; Protein Binding; Recombinant Proteins

1999
Disturbed communication between actin- and nucleotide-binding sites in a myosin II with truncated 50/20-kDa junction.
    The Journal of biological chemistry, 1999, Jul-16, Volume: 274, Issue:29

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Base Sequence; Binding Sites; Dictyostelium; DNA Primers; Enzyme Activation; Kinetics; Mutagenesis, Site-Directed; Myosins; Rabbits

1999
Engineering of the myosin-ibeta nucleotide-binding pocket to create selective sensitivity to N(6)-modified ADP analogs.
    The Journal of biological chemistry, 1999, Oct-29, Volume: 274, Issue:44

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acid Sequence; Animals; Binding Sites; Chickens; Dictyostelium; Hydrolysis; Isoenzymes; Models, Molecular; Molecular Sequence Data; Movement; Mutation; Mutation, Missense; Myosins; Protein Binding; Protein Engineering; Rats

1999
X-ray structures of the Dictyostelium discoideum myosin motor domain with six non-nucleotide analogs.
    The Journal of biological chemistry, 2000, Jan-07, Volume: 275, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Beryllium; Binding Sites; Crystallography; Dictyostelium; Dinitrobenzenes; Fluorides; Models, Molecular; Molecular Motor Proteins; Myosins; Protein Structure, Tertiary; Water

2000
Charge changes in loop 2 affect the thermal unfolding of the myosin motor domain bound to F-actin.
    Biochemistry, 2000, Apr-18, Volume: 39, Issue:15

    Topics: Actins; Adenosine Diphosphate; Animals; Binding Sites; Calorimetry, Differential Scanning; Dictyostelium; Molecular Motor Proteins; Molecular Weight; Mutagenesis, Insertional; Myosins; Peptide Fragments; Phosphates; Protein Binding; Protein Denaturation; Protein Folding; Protein Structure, Tertiary; Static Electricity; Temperature; Thermodynamics

2000
Kinetic and spectroscopic evidence for three actomyosin:ADP states in smooth muscle.
    The Journal of biological chemistry, 2000, Aug-18, Volume: 275, Issue:33

    Topics: Actins; Actomyosin; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Catalytic Domain; Chickens; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Kinetics; Microscopy, Electron; Models, Chemical; Muscle Fibers, Fast-Twitch; Muscle Fibers, Slow-Twitch; Muscle, Smooth; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Spectrometry, Fluorescence

2000
A FRET-based sensor reveals large ATP hydrolysis-induced conformational changes and three distinct states of the molecular motor myosin.
    Cell, 2000, Sep-01, Volume: 102, Issue:5

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Substitution; Animals; Binding Sites; Biosensing Techniques; Crystallography, X-Ray; Cysteine; Dictyostelium; Energy Transfer; Fluorescence; Hydrolysis; Kinetics; Models, Chemical; Models, Molecular; Molecular Motor Proteins; Myosins; Protein Conformation; Protein Engineering

2000
Resolution of conformational states of Dictyostelium myosin II motor domain using tryptophan (W501) mutants: implications for the open-closed transition identified by crystallography.
    Biochemistry, 2000, Dec-26, Volume: 39, Issue:51

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Aluminum Compounds; Animals; Binding Sites; Crystallography, X-Ray; Dictyostelium; Fluorides; Hydrolysis; Kinetics; Molecular Motor Proteins; Mutagenesis, Site-Directed; Myosins; Protein Conformation; Protein Structure, Tertiary; Spectrometry, Fluorescence; Tryptophan

2000
Detection of the swings of the lever arm of a myosin motor by fluorescence resonance energy transfer of green and blue fluorescent proteins.
    Methods (San Diego, Calif.), 2000, Volume: 22, Issue:4

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Biophysics; Dictyostelium; Energy Transfer; Green Fluorescent Proteins; Luminescent Proteins; Models, Chemical; Models, Molecular; Molecular Motor Proteins; Movement; Myosins; Recombinant Fusion Proteins; Spectrometry, Fluorescence

2000
A myosin II mutation uncouples ATPase activity from motility and shortens step size.
    Nature cell biology, 2001, Volume: 3, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Catalytic Domain; Dictyostelium; Kinetics; Models, Biological; Models, Molecular; Molecular Motor Proteins; Movement; Mutation; Myosins; Plasmids; Protein Conformation; Protein Structure, Tertiary; Spectrophotometry; Transformation, Genetic

2001
The dynamics of the relay loop tryptophan residue in the Dictyostelium myosin motor domain and the origin of spectroscopic signals.
    The Journal of biological chemistry, 2001, Jun-01, Volume: 276, Issue:22

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Anisotropy; Cloning, Molecular; Dictyostelium; Kinetics; Models, Chemical; Myosins; Phenylalanine; Protein Structure, Tertiary; Spectrometry, Fluorescence; Spectrophotometry; Time Factors; Tryptophan

2001
Binding of nucleotides to nucleoside diphosphate kinase: a calorimetric study.
    Biochemistry, 2001, Apr-17, Volume: 40, Issue:15

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Adenylyl Imidodiphosphate; Animals; Binding Sites; Calorimetry, Differential Scanning; Crystallography, X-Ray; Dictyostelium; Guanosine Diphosphate; Humans; Inosine Diphosphate; Myxococcus xanthus; Nucleoside-Diphosphate Kinase; Purine Nucleotides; Thermodynamics; Thymine Nucleotides; Titrimetry

2001
A fluorescence temperature-jump study of conformational transitions in myosin subfragment 1.
    The Biochemical journal, 2001, Aug-15, Volume: 358, Issue:Pt 1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Beryllium; Chickens; Dictyostelium; Fluorides; Kinetics; Ligands; Models, Chemical; Muscle, Skeletal; Myosin Subfragments; Myosins; Protein Conformation; Rabbits; Spectrometry, Fluorescence; Temperature; Thermodynamics; Time Factors

2001
Evidence for a novel, strongly bound acto-S1 complex carrying ADP and phosphate stabilized in the G680V mutant of Dictyostelium myosin II.
    Biochemistry, 2002, Jul-30, Volume: 41, Issue:30

    Topics: Actins; Actomyosin; Adenosine Diphosphate; Adenosine Triphosphatases; Animals; Dictyostelium; Electrophoresis, Polyacrylamide Gel; Kinetics; Light; Mutation; Myosin Type II; Phosphates; Pyrenes; Rabbits; Scattering, Radiation

2002
Solution properties of full length and truncated forms of myosin subfragment 1 from Dictyostelium discoideum.
    Journal of muscle research and cell motility, 2001, Volume: 22, Issue:8

    Topics: Actins; Adenosine Diphosphate; Animals; Dictyostelium; Enzyme Inhibitors; Ethylmaleimide; Fluorescent Dyes; Myosin Subfragments; Peptide Fragments; Protein Binding; Protein Structure, Tertiary; Rabbits; Solubility; Temperature; Trinitrobenzenes; Ultraviolet Rays

2001
The mechanism of phosphorylation of natural nucleosides and anti-HIV analogues by nucleoside diphosphate kinase is independent of their sugar substituents.
    Chembiochem : a European journal of chemical biology, 2002, Jul-02, Volume: 3, Issue:7

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aluminum Compounds; Animals; Anti-HIV Agents; Binding Sites; Computers, Molecular; Cyclic AMP; Dictyostelium; Histidine; Models, Chemical; Nucleoside-Diphosphate Kinase; Nucleosides; Phosphorylation; Quantum Theory; Thermodynamics; Thymidine

2002
Dictyostelium myosin II mutations that uncouple the converter swing and ATP hydrolysis cycle.
    Biochemistry, 2003, Jan-14, Volume: 42, Issue:1

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Animals; Dictyostelium; Hydrolysis; Isoleucine; Kinetics; Molecular Motor Proteins; Mutagenesis, Site-Directed; Myosin Type II; Myosins; Phenylalanine; Point Mutation; Protozoan Proteins; Vanadates

2003
Interaction of myosin subfragment 1 with forms of monomeric actin.
    Biochemistry, 2003, Mar-18, Volume: 42, Issue:10

    Topics: Actins; Adenosine Diphosphate; Adsorption; Animals; Binding, Competitive; Cattle; Chromatography, Affinity; Cross-Linking Reagents; Deoxyribonuclease I; Dictyostelium; Enzymes, Immobilized; Ethyldimethylaminopropyl Carbodiimide; Hydrolysis; Magnesium; Myosin Subfragments; ortho-Aminobenzoates; Osmolar Concentration; Protozoan Proteins; Pyrenes; Rabbits; Spectrometry, Fluorescence; Titrimetry; Trypsin; Vitamin D-Binding Protein

2003
Requirement of domain-domain interaction for conformational change and functional ATP hydrolysis in myosin.
    The Journal of biological chemistry, 2003, Aug-15, Volume: 278, Issue:33

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Cell Division; Cell Movement; Dictyostelium; Fluorescence; Fluorescence Resonance Energy Transfer; Hydrolysis; Mutagenesis, Site-Directed; Myosins; Phenotype; Protein Structure, Tertiary; Tryptophan

2003
Roles of the hydrophobic triplet in the motor domain of myosin in the interaction between myosin and actin.
    Journal of biochemistry, 2003, Volume: 134, Issue:1

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acids; Animals; Cells, Cultured; Dictyostelium; Hydrophobic and Hydrophilic Interactions; Kinetics; Molecular Motor Proteins; Muscle, Skeletal; Mutagenesis, Site-Directed; Myosins; Protein Binding; Protein Structure, Tertiary; Rabbits; Recombinant Proteins; Spectrometry, Fluorescence; Spectrophotometry

2003
A structural model for actin-induced nucleotide release in myosin.
    Nature structural biology, 2003, Volume: 10, Issue:10

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Dictyostelium; Myosins; Protein Binding; Protein Structure, Tertiary

2003
Molecular dynamics analysis of structural factors influencing back door pi release in myosin.
    Biophysical journal, 2004, Volume: 86, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Dictyostelium; Diphosphates; Models, Molecular; Myosins; Phosphates; Water

2004
Changes in Mg2+ ion concentration and heavy chain phosphorylation regulate the motor activity of a class I myosin.
    The Journal of biological chemistry, 2005, Feb-18, Volume: 280, Issue:7

    Topics: Actins; Actomyosin; Adenosine Diphosphate; Adenosine Triphosphate; Amino Acid Sequence; Animals; Cations, Divalent; Dictyostelium; Kinetics; Magnesium; Molecular Motor Proteins; Movement; Mutation; Myosin Heavy Chains; Myosin Type I; Phosphorylation; Protein Binding; Thermodynamics; Titrimetry

2005
The effect of F-actin on the relay helix position of myosin II, as revealed by tryptophan fluorescence, and its implications for mechanochemical coupling.
    Biochemistry, 2004, Dec-14, Volume: 43, Issue:49

    Topics: Actins; Actomyosin; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dictyostelium; Molecular Motor Proteins; Myosin Type II; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Protozoan Proteins; Rabbits; Signal Transduction; Spectrometry, Fluorescence; Tryptophan

2004
Biological, biochemical, and kinetic effects of mutations of the cardiomyopathy loop of Dictyostelium myosin II: importance of ALA400.
    The Journal of biological chemistry, 2005, Jul-22, Volume: 280, Issue:29

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Alanine; Amino Acid Sequence; Amino Acid Substitution; Animals; Cardiomyopathy, Hypertrophic, Familial; Dictyostelium; Humans; Kinetics; Mutation; Myosin Type II; Phosphates; Recombinant Fusion Proteins

2005
Structural rearrangements in the active site of smooth-muscle myosin.
    Biophysical journal, 2005, Volume: 89, Issue:3

    Topics: Acrylamide; Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Binding Sites; Cell Line; Chickens; Crystallography, X-Ray; Dictyostelium; DNA, Complementary; Dose-Response Relationship, Drug; Fluorescence Resonance Energy Transfer; Hydrolysis; Insecta; Kinetics; Models, Chemical; Models, Molecular; Mutagenesis, Site-Directed; Mutation; Myosin Type II; Myosins; Nucleotides; Protein Conformation; Protein Structure, Tertiary; Temperature; Time Factors; Tryptophan

2005
Dictyostelium myosin-IE is a fast molecular motor involved in phagocytosis.
    Journal of cell science, 2006, Feb-01, Volume: 119, Issue:Pt 3

    Topics: Adenosine Diphosphate; Animals; Dictyostelium; Magnesium; Myosin Type I; Phagocytosis; Phosphorylation; Protein Processing, Post-Translational

2006
Adenosine phosphonoacetic acid is slowly metabolized by NDP kinase.
    Medicinal chemistry (Shariqah (United Arab Emirates)), 2005, Volume: 1, Issue:6

    Topics: Adenosine; Adenosine Diphosphate; Animals; Binding Sites; Catalysis; Crystallization; Dictyostelium; Enzyme Inhibitors; Humans; Kinetics; Models, Molecular; Molecular Structure; Nucleoside-Diphosphate Kinase; Phosphonoacetic Acid; Structure-Activity Relationship; X-Ray Diffraction

2005
Simulations of the myosin II motor reveal a nucleotide-state sensing element that controls the recovery stroke.
    Journal of molecular biology, 2006, Aug-18, Volume: 361, Issue:3

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Catalytic Domain; Dictyostelium; Hydrogen Bonding; Hydrolysis; Models, Molecular; Molecular Motor Proteins; Myosin Type II; Protein Binding; Protozoan Proteins

2006
A point mutation in the SH1 helix alters elasticity and thermal stability of myosin II.
    The Journal of biological chemistry, 2006, Oct-13, Volume: 281, Issue:41

    Topics: Adenosine Diphosphate; Amino Acid Sequence; Animals; Ca(2+) Mg(2+)-ATPase; Dictyostelium; Kinetics; Molecular Sequence Data; Movement; Myosin Heavy Chains; Myosin Type II; Myosins; Plasmids; Point Mutation; Protein Structure, Secondary; Sequence Homology, Amino Acid

2006
Functional characterization of the N-terminal region of myosin-2.
    The Journal of biological chemistry, 2006, Nov-24, Volume: 281, Issue:47

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Cytokinesis; Dictyostelium; Genetic Complementation Test; Molecular Sequence Data; Myosin Type II; Myosins; Protein Structure, Tertiary; Sequence Homology, Amino Acid; src Homology Domains

2006
Reversible movement of switch 1 loop of myosin determines actin interaction.
    The EMBO journal, 2007, Jan-10, Volume: 26, Issue:1

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cryoelectron Microscopy; Crystallography, X-Ray; Dictyostelium; Magnesium; Models, Chemical; Models, Molecular; Myosins; Protein Binding; Protein Conformation; Protein Structure, Tertiary; Tryptophan

2007
A closer look at energy transduction in muscle.
    Proceedings of the National Academy of Sciences of the United States of America, 2007, Jul-31, Volume: 104, Issue:31

    Topics: Actins; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Dictyostelium; Models, Molecular; Muscles; Mutation; Myosins; Phosphates; Protein Binding; Protein Structure, Tertiary

2007
The association of actin and myosin in the presence of gamma-amido-ATP proceeds mainly via a complex with myosin in the closed conformation.
    Biochemistry, 2007, Aug-21, Volume: 46, Issue:33

    Topics: Actins; Adenosine Diphosphate; Adenylyl Imidodiphosphate; Animals; Dictyostelium; Fluorescence; Myosins; ortho-Aminobenzoates; Protein Conformation; Spectrometry, Fluorescence; Tryptophan

2007
Kinetic characterization of the function of myosin loop 4 in the actin-myosin interaction.
    Biochemistry, 2008, Jan-08, Volume: 47, Issue:1

    Topics: Actins; Actomyosin; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Dictyostelium; Kinetics; Mutation; Myosins; Protein Binding; Protein Structure, Secondary; Protein Structure, Tertiary; Protozoan Proteins

2008
The mechanism of the reverse recovery step, phosphate release, and actin activation of Dictyostelium myosin II.
    The Journal of biological chemistry, 2008, Mar-28, Volume: 283, Issue:13

    Topics: Actins; Adenosine Diphosphate; Animals; Buffers; Crystallography, X-Ray; Dictyostelium; Kinetics; Magnetic Resonance Spectroscopy; Models, Molecular; Mutation; Myosin Type II; Phosphates; Protein Binding; Protein Structure, Tertiary

2008
Permeation properties of a P2X receptor in the green algae Ostreococcus tauri.
    The Journal of biological chemistry, 2008, May-30, Volume: 283, Issue:22

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations; Cell Line; Cell Membrane Permeability; Chlorophyta; Cloning, Molecular; Dictyostelium; Evolution, Molecular; Humans; Purinergic P2 Receptor Agonists; Purinergic P2 Receptor Antagonists; Receptors, Purinergic P2; Receptors, Purinergic P2X; Sequence Homology, Amino Acid

2008
Purinergic-mediated Ca2+ influx in Dictyostelium discoideum.
    Cell calcium, 2008, Volume: 44, Issue:6

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Aequorin; Animals; Apoproteins; Calcium; Calcium Signaling; Cyclic AMP; Dictyostelium; Extracellular Space; Gadolinium; Genes, Protozoan; Intracellular Space; Phospholipases A2; Receptors, Purinergic; Recombinant Proteins; Recombination, Genetic; Zinc

2008
Dictyostelium myosin-5b is a conditional processive motor.
    The Journal of biological chemistry, 2008, Oct-03, Volume: 283, Issue:40

    Topics: Actin Cytoskeleton; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Cations, Divalent; Dictyostelium; Isoenzymes; Magnesium; Myosins; Protozoan Proteins

2008
Myosin complexed with ADP and blebbistatin reversibly adopts a conformation resembling the start point of the working stroke.
    Proceedings of the National Academy of Sciences of the United States of America, 2010, Apr-13, Volume: 107, Issue:15

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Animals; Binding Sites; Dictyostelium; Fluorescent Dyes; Heterocyclic Compounds, 4 or More Rings; Kinetics; Microscopy, Electron; Microscopy, Fluorescence; Models, Biological; Molecular Conformation; Myosins; Protein Conformation; Rabbits

2010
Nucleotide pocket thermodynamics measured by EPR reveal how energy partitioning relates myosin speed to efficiency.
    Journal of molecular biology, 2011, Mar-18, Volume: 407, Issue:1

    Topics: Actins; Actomyosin; Adenosine Diphosphate; Animals; Chickens; Dictyostelium; Electron Spin Resonance Spectroscopy; Models, Biological; Muscle, Skeletal; Myosins; Nucleotides; Protein Binding; Protein Conformation; Rabbits; Spin Labels; Swine; Thermodynamics

2011
X-ray structure of a functional full-length dynein motor domain.
    Nature structural & molecular biology, 2011, Volume: 18, Issue:6

    Topics: Adenosine Diphosphate; Crystallography, X-Ray; Dictyostelium; Dyneins; Models, Molecular; Protein Structure, Quaternary; Protozoan Proteins

2011
Structural basis for the allosteric interference of myosin function by reactive thiol region mutations G680A and G680V.
    The Journal of biological chemistry, 2011, Oct-07, Volume: 286, Issue:40

    Topics: Adenosine Diphosphate; Allosteric Site; Binding Sites; Cold Temperature; Crystallography, X-Ray; Dictyostelium; Kinetics; Models, Molecular; Mutagenesis; Mutation; Myosins; Principal Component Analysis; Sulfhydryl Compounds; Temperature; Thermodynamics

2011
The 2.8 Å crystal structure of the dynein motor domain.
    Nature, 2012, Mar-07, Volume: 484, Issue:7394

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Binding Sites; Crystallography, X-Ray; Cytoplasmic Dyneins; Dictyostelium; Hydrolysis; Microtubules; Models, Biological; Models, Molecular; Movement; Protein Structure, Tertiary; Structure-Activity Relationship

2012
Allosteric communication in Dictyostelium myosin II.
    Journal of muscle research and cell motility, 2012, Volume: 33, Issue:5

    Topics: Actins; Actomyosin; Adenosine Diphosphate; Adenosine Triphosphate; Allosteric Regulation; Catalytic Domain; Cysteine; Dictyostelium; Myosin Type II; Protein Binding

2012
ATP-driven remodeling of the linker domain in the dynein motor.
    Structure (London, England : 1993), 2012, Oct-10, Volume: 20, Issue:10

    Topics: Adenosine Diphosphate; Adenosine Triphosphate; Axonemal Dyneins; Axoneme; Chlamydomonas reinhardtii; Cryoelectron Microscopy; Dictyostelium; Microscopy, Video; Microtubules; Models, Molecular; Plant Proteins; Protein Binding; Protein Structure, Quaternary; Protein Structure, Tertiary; Protozoan Proteins; Structural Homology, Protein

2012
Global fit analysis of myosin-5b motility reveals thermodynamics of Mg2+-sensitive acto-myosin-ADP states.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: Adenosine Diphosphate; Dictyostelium; Magnesium; Myosin Type V; Thermodynamics

2013
Bulkiness or aromatic nature of tyrosine-143 of actin is important for the weak binding between F-actin and myosin-ADP-phosphate.
    Biochemical and biophysical research communications, 2013, Nov-29, Volume: 441, Issue:4

    Topics: Actins; Adenosine Diphosphate; Dictyostelium; Enzyme Activators; Myosin Subfragments; Phalloidine; Phosphates; Polymerization; Potassium Chloride; Protein Binding; Sodium Chloride; Tyrosine

2013
Modulation of post-powerstroke dynamics in myosin II by 2'-deoxy-ADP.
    Archives of biochemistry and biophysics, 2021, 03-15, Volume: 699

    Topics: Adenosine Diphosphate; Binding Sites; Deoxyadenine Nucleotides; Dictyostelium; Molecular Dynamics Simulation; Myosin Type II; Pliability; Protein Binding; Protein Conformation; Protein Domains

2021
Actin-binding domain of Rng2 sparsely bound on F-actin strongly inhibits actin movement on myosin II.
    Life science alliance, 2023, Volume: 6, Issue:1

    Topics: Actin Cytoskeleton; Actins; Actomyosin; Adenosine Diphosphate; Cytoskeletal Proteins; Dictyostelium; Microfilament Proteins; Myosin Type II; Schizosaccharomyces; Skeletal Muscle Myosins

2023