1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and 8-bromo cyclic adenosine monophosphate

1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone has been researched along with 8-bromo cyclic adenosine monophosphate in 24 studies

Compound Research Comparison

Studies (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Trials (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Recent Studies (post-2010) (1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone)	Studies (8-bromo cyclic adenosine monophosphate)	Trials (8-bromo cyclic adenosine monophosphate)	Recent Studies (post-2010) (8-bromo cyclic adenosine monophosphate)
7,666	0	1,658	3,707	5	198

Protein Interaction Comparison

Protein	Taxonomy	8-bromo cyclic adenosine monophosphate (IC50)
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	Homo sapiens (human)	7.7
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	Homo sapiens (human)	7.7
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	Homo sapiens (human)	7.7
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	Homo sapiens (human)	7.7

Research

Studies (24)

Timeframe	Studies, this research(%)	All Research%
pre-1990	3 (12.50)	18.7374
1990's	14 (58.33)	18.2507
2000's	5 (20.83)	29.6817
2010's	2 (8.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Berks, M; Kay, RR; Masento, MS; Morris, HR; Taylor, GW; Traynor, D	1
Kubohara, Y; Maeda, M; Okamoto, K	1
Okamoto, K; Williams, J; Yamada, Y	1
Kay, RR; Thompson, CR	1
Amagai, A; Maeda, Y; Suzuki, T	1
Firtel, RA; Mann, SK; Taylor, SS; Yonemoto, WM	1
Barclay, SL; Riley, BB	1
Barclay, SL; Jensen, BR; Riley, BB	1
Dottin, RP; Haribabu, B	1
Kimmel, AR; Loomis, WF; Richardson, DL	1
Gollnick, F; Knoll, G; Meyer, R; Schlatterer, C; Schmidt, E	1
Okamoto, K; Yamada, Y	1
Escalante, R; Loomis, WF; Shaulsky, G; Wang, N	1
Singleton, CK; Zinda, MJ	1
Escalante, R; Sastre, L	1
Balint-Kurti, P; Ginsburg, GT; Kimmel, AR; Liu, J	1
Aubry, L; Ceccarelli, A; Early, A; Firtel, RA; Jermyn, KA; Kawata, T; Mohanty, S; Schaap, P; Williams, JG	1
Cotter, DA; Kopko, SH; Meima, M; Sands, TW; Schaap, P; van Es, S; Virdy, KJ	1
Keller, H; Oehme, F; Ott, A; Schuster, SC	1
Devreotes, P; Janetopoulos, C; Jin, T	1
Meima, ME; Schaap, P; Weening, KE	1
Escalante, R; Moreno, N; Sastre, L	1
Gillet, A; Giusti, C; Golstein, P; Luciani, MF; Ravens, S	1
Baumgardner, K; Firtel, RA; Lacal, J; Lin, C	1

Other Studies

24 other study(ies) available for 1-((3,5-dichloro)-2,6-dihydroxy-4-methoxyphenyl)-1-hexanone and 8-bromo cyclic adenosine monophosphate

Article	Year
Signals controlling cell differentiation and pattern formation in Dictyostelium. Developmental genetics, 1988, Volume: 9, Issue:4-5 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Differentiation; Cyclic AMP; Dictyostelium; Hexanones; Ketones; Pentanones; Spores, Fungal	1988
Analysis of the maturation process of prestalk cells in Dictyostelium discoideum. Experimental cell research, 1993, Volume: 207, Issue:1 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine; Animals; Calcium; Cell Differentiation; Cells, Cultured; Dictyostelium; Dimethadione; Hexanones; Pentanones; Protein Kinases	1993
Characterization of a Dictyostelium factor that acts synergistically with DIF to induce terminal stalk cell differentiation. Developmental biology, 1997, Apr-15, Volume: 184, Issue:2 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; beta-Galactosidase; Cell Differentiation; Cells, Cultured; Chromatography, High Pressure Liquid; Culture Media, Conditioned; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; Enzyme Activation; Extracellular Matrix Proteins; Fungal Proteins; Gene Expression Regulation, Fungal; Genes, Reporter; Hexanones; Molecular Weight; Mutation; Protozoan Proteins; Signal Transduction; Transformation, Genetic	1997
Cell-fate choice in Dictyostelium: intrinsic biases modulate sensitivity to DIF signaling. Developmental biology, 2000, Nov-01, Volume: 227, Issue:1 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biomarkers; Cell Cycle; Cell Differentiation; Cell Lineage; Dictyostelium; Enzyme Induction; Gene Expression Regulation, Developmental; Glucose; Green Fluorescent Proteins; Hexanones; Luminescent Proteins; Lyases; Oxidoreductases; Pentanones; Signal Transduction; Spores	2000
Cyclic AMP and Ca2+ as regulators of zygote formation in the cellular slime mold Dictyostelium mucoroides. Differentiation; research in biological diversity, 1992, Volume: 49, Issue:3 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cations, Monovalent; Cyclic AMP; Dictyostelium; Kinetics; Membrane Fusion	1992
DdPK3, which plays essential roles during Dictyostelium development, encodes the catalytic subunit of cAMP-dependent protein kinase. Proceedings of the National Academy of Sciences of the United States of America, 1992, Nov-15, Volume: 89, Issue:22 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Binding Sites; Cloning, Molecular; Cyclic AMP; Dictyostelium; Escherichia coli; Gene Expression; Genetic Vectors; Kinetics; Macromolecular Substances; Mice; Molecular Sequence Data; Protein Kinases; Sequence Homology, Amino Acid; Spores, Fungal	1992
Conditions that alter intracellular cAMP levels affect expression of the cAMP phosphodiesterase gene in Dictyostelium. Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:12 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Ammonium Chloride; Caffeine; Cell Membrane; Cyclic AMP; Cytoplasm; Dictyostelium; Gene Expression; Gene Expression Regulation, Fungal; Genes, Fungal; Kinetics; Models, Biological; Progesterone	1990
Conditions that elevate intracellular cyclic AMP levels promote spore formation in Dictyostelium. Differentiation; research in biological diversity, 1989, Volume: 41, Issue:1 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Caffeine; Cell Survival; Cyclic AMP; Dictyostelium; Mutation; Spores, Fungal	1989
Pharmacological characterization of cyclic AMP receptors mediating gene regulation in Dictyostelium discoideum. Molecular and cellular biology, 1986, Volume: 6, Issue:7 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cyclic AMP; Dictyostelium; Discoidins; Dose-Response Relationship, Drug; Fungal Proteins; Gene Expression Regulation; Lectins; Mutation; Protozoan Proteins; Receptors, Cyclic AMP; Time Factors	1986
Progression of an inductive signal activates sporulation in Dictyostelium discoideum. Development (Cambridge, England), 1994, Volume: 120, Issue:10 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Base Sequence; beta-Galactosidase; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; Gene Deletion; Gene Expression; Genes, Fungal; Molecular Sequence Data; Promoter Regions, Genetic; Signal Transduction; Spores, Fungal	1994
Challenge with high concentrations of cyclic AMP induces transient changes in the cytosolic free calcium concentration in Dictyostelium discoideum. Journal of cell science, 1994, Volume: 107 ( Pt 8) Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Calcium; Cell Differentiation; Cyclic AMP; Cytosol; Dictyostelium; Microscopy, Electron; Microscopy, Video; Signal Transduction	1994
Analysis of cellular interactions involved in differential control of prestalk genes in Dictyostelium discoideum. Developmental biology, 1994, Volume: 161, Issue:1 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Count; Cell Differentiation; Cells, Cultured; Cyclic AMP; Dictyostelium; Gene Expression Regulation; RNA, Messenger	1994
A two-component histidine kinase gene that functions in Dictyostelium development. The EMBO journal, 1996, Aug-01, Volume: 15, Issue:15 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Base Sequence; Dictyostelium; Gene Expression Regulation, Fungal; Genes, Recessive; Histidine Kinase; In Situ Hybridization; Molecular Sequence Data; Mutation; Phenotype; Phosphorylation; Plasmids; Protein Kinases	1996
The hybrid histidine kinase dhkB regulates spore germination in Dictyostelium discoideum. Developmental biology, 1998, Apr-15, Volume: 196, Issue:2 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Cloning, Molecular; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; Enzyme Activation; Gene Expression Regulation, Developmental; Gene Expression Regulation, Enzymologic; Genes, Protozoan; Histidine Kinase; Molecular Sequence Data; Osmotic Pressure; Protein Kinases; Protozoan Proteins; RNA, Messenger; RNA, Protozoan; Sequence Alignment; Sequence Analysis, DNA; Spores	1998
A Serum Response Factor homolog is required for spore differentiation in Dictyostelium. Development (Cambridge, England), 1998, Volume: 125, Issue:19 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Amino Acid Sequence; Animals; Cell Differentiation; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; DNA-Binding Proteins; Enzyme Activation; Gene Expression Regulation, Developmental; Genes, Protozoan; Humans; Molecular Sequence Data; Mutation; Nuclear Proteins; Protozoan Proteins; RNA, Messenger; RNA, Protozoan; Sequence Homology, Amino Acid; Serum Response Factor; Spores	1998
Non-autonomous regulation of a graded, PKA-mediated transcriptional activation signal for cell patterning. Development (Cambridge, England), 1998, Volume: 125, Issue:20 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Biomarkers; Body Patterning; Catalytic Domain; Cell Differentiation; Chimera; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; DNA-Binding Proteins; Gene Expression Regulation, Developmental; Genes, Protozoan; Leucine Zippers; Models, Biological; Promoter Regions, Genetic; Sequence Deletion; Signal Transduction; Spores; Transcription Factors; Transcriptional Activation	1998
Evidence that the Dictyostelium Dd-STATa protein is a repressor that regulates commitment to stalk cell differentiation and is also required for efficient chemotaxis. Development (Cambridge, England), 1999, Volume: 126, Issue:15 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cell Differentiation; Chemotaxis; Dictyostelium; DNA, Complementary; DNA, Protozoan; Genes, Protozoan; Genes, Reporter; Genetic Markers; Lac Operon; Microscopy, Video; Mutagenesis, Insertional; Mutation; Protozoan Proteins; Repressor Proteins	1999
High cAMP in spores of Dictyostelium discoideum: association with spore dormancy and inhibition of germination. Microbiology (Reading, England), 1999, Volume: 145 ( Pt 8) Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenylyl Cyclases; Animals; Cyclic AMP; Dictyostelium; Gene Expression Regulation; Heat-Shock Response; RNA, Messenger; RNA, Protozoan; Spores; Transcription, Genetic	1999
Osmotic stress response in Dictyostelium is mediated by cAMP. The EMBO journal, 2000, Nov-01, Volume: 19, Issue:21 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cyclic AMP-Dependent Protein Kinases; Dictyostelium; DNA-Binding Proteins; Gene Expression; Osmotic Pressure; Phenotype; Protein Kinases; Protein Structure, Tertiary; Protozoan Proteins; Signal Transduction	2000
Receptor-mediated activation of heterotrimeric G-proteins in living cells. Science (New York, N.Y.), 2001, Mar-23, Volume: 291, Issue:5512 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Animals; Bacterial Proteins; Cyclic AMP; Deoxyadenine Nucleotides; Dictyostelium; Energy Transfer; Fluorescence; Guanosine 5'-O-(3-Thiotriphosphate); Heterotrimeric GTP-Binding Proteins; Kinetics; Ligands; Luminescent Proteins; Microscopy, Fluorescence; Phosphorylation; Receptors, Cyclic AMP; Recombinant Fusion Proteins; Signal Transduction; Spectrometry, Fluorescence; Transformation, Genetic	2001
Characterization of a cAMP-stimulated cAMP phosphodiesterase in Dictyostelium discoideum. The Journal of biological chemistry, 2003, Apr-18, Volume: 278, Issue:16 Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 8-Bromo Cyclic Adenosine Monophosphate; Animals; Cyclic AMP; Cytosol; Databases as Topic; Dictyostelium; DNA, Complementary; Dose-Response Relationship, Drug; Exons; Gene Expression Regulation, Developmental; Hydrogen-Ion Concentration; Introns; Kinetics; Magnesium; Manganese; Metals; Molecular Sequence Data; Mutation; Precipitin Tests; Protein Structure, Tertiary; Recombinant Fusion Proteins; RNA; Time Factors; Zinc	2003
Dictyostelium discoideum developmentally regulated genes whose expression is dependent on MADS box transcription factor SrfA. Eukaryotic cell, 2003, Volume: 2, Issue:6 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Alternative Splicing; Amino Acid Motifs; Amino Acid Sequence; Animals; Base Sequence; Conserved Sequence; Cyclic AMP-Dependent Protein Kinases; Cysteine; Dictyostelium; Enzyme Activation; Exons; Gene Expression Regulation, Developmental; Genes, Protozoan; In Situ Hybridization; MADS Domain Proteins; Models, Biological; Molecular Sequence Data; Protein Structure, Tertiary; Protozoan Proteins; RNA, Messenger; Spores, Protozoan; Transcription Factors	2003
Autophagic cell death in Dictyostelium requires the receptor histidine kinase DhkM. Molecular biology of the cell, 2010, Jun-01, Volume: 21, Issue:11 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Actins; Autophagy; Cellulose; Dictyostelium; Histidine Kinase; Mutagenesis, Insertional; Protein Kinases; Protozoan Proteins; Signal Transduction	2010
Phosphodiesterase PdeD, dynacortin, and a Kelch repeat-containing protein are direct GSK3 substrates in Dictyostelium that contribute to chemotaxis towards cAMP. Environmental microbiology, 2018, Volume: 20, Issue:5 Topics: 8-Bromo Cyclic Adenosine Monophosphate; Cell Cycle Proteins; Chemotaxis; Cyclic AMP; Dictyostelium; Gene Expression Regulation; Glycogen Synthase Kinase 3; Kelch Repeat; Phosphoric Diester Hydrolases; Protozoan Proteins; Signal Transduction	2018