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1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine and uracil

1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine has been researched along with uracil in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bader, JP; Boyer, PL; Buckheit, RW; Chu, SH; Fliakas-Boltz, V; Hughes, SH; Mayers, DL; Pan, BC; Weislow, O; Yeagy-Bargo, S1
Danel, K; Larsen, E; Nielsen, C; Pedersen, EB; Vestergaard, BF1
Danel, K; Nielsen, C; Pedersen, EB1
Balzarini, J; Chen, FE; De Clercq, E; Meng, G; Pannecouque, C1

Other Studies

4 other study(ies) available for 1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine and uracil

ArticleYear
Resistance to 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine derivatives is generated by mutations at multiple sites in the HIV-1 reverse transcriptase.
    Virology, 1995, Jun-20, Volume: 210, Issue:1

    Topics: Antiviral Agents; Cell Line; Dose-Response Relationship, Drug; Drug Resistance, Microbial; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Mutagenesis, Site-Directed; Nevirapine; Pyridines; Recombinant Proteins; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship; Thymine; Uracil; Zidovudine

1995
Synthesis and potent anti-HIV-1 activity of novel 6-benzyluracil analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
    Journal of medicinal chemistry, 1996, Jun-07, Volume: 39, Issue:12

    Topics: Alkylation; Antiviral Agents; Cell Division; Drug Design; HIV-1; Humans; Magnetic Resonance Spectroscopy; Molecular Structure; Structure-Activity Relationship; T-Lymphocytes; Thymine; Uracil; Virus Replication

1996
Synthesis and anti-HIV-1 activity of novel 2,3-dihydro-7H-thiazolo[3,2-a]pyrimidin-7-ones.
    Journal of medicinal chemistry, 1998, Jan-15, Volume: 41, Issue:2

    Topics: Alkylation; Anti-HIV Agents; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Magnetic Resonance Spectroscopy; Mesylates; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; T-Lymphocytes; Thiazoles; Thymine; Uracil; Virus Replication

1998
Nonnucleoside HIV-1 reverse transcriptase inhibitors: Part I. Synthesis and structure-activity relationship of 1-alkoxymethyl-5-alkyl-6-naphthylmethyl uracils as HEPT analogues.
    Chemical & pharmaceutical bulletin, 2003, Volume: 51, Issue:7

    Topics: Cell Line; HIV Reverse Transcriptase; Humans; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thymine; Uracil

2003