1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine has been researched along with emivirine in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 4 (57.14) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baba, M; De Clercq, E; Inouye, N; Miyasaka, T; Sekiya, K; Shigeta, S; Takashima, H; Tanaka, H; Ubasawa, M; Walker, RT | 1 |
| Esnouf, RM; Hopkins, AL; Jones, EY; Miyasaka, T; Ren, J; Ross, C; Stammers, DK; Stuart, DI; Tanaka, H; Walker, RT; Willcox, BE | 1 |
| Jorgensen, WL; Rizzo, RC; Tirado-Rives, J | 1 |
| Jorgensen, WL; Kroeger Smith, MB; Rizzo, RC; Smith, RH; Tirado-Rives, J; Udier-Blagović, M; Wang, DP; Watkins, EK | 1 |
| Artico, M; Cadeddu, A; La Colla, P; Mai, A; Marturana, F; Massa, S; Mura, M; Musiu, C; Ragno, R; Sbardella, G | 1 |
| Kang, X; Kollman, PA; Kuntz, ID; Wang, J | 1 |
| Danel, K; Nielsen, C; Pedersen, EB | 1 |
7 other study(ies) available for 1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine and emivirine
| Article | Year |
|---|---|
Synthesis and antiviral activity of 6-benzyl analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.
Topics: Animals; Antiviral Agents; Benzyl Compounds; HIV Infections; HIV-1; Humans; Lymphocytes; Mice; Microbial Sensitivity Tests; Structure-Activity Relationship; Thymine | 1995 |
Complexes of HIV-1 reverse transcriptase with inhibitors of the HEPT series reveal conformational changes relevant to the design of potent non-nucleoside inhibitors.
Topics: Antiviral Agents; HIV Reverse Transcriptase; HIV-1; Humans; Hydrogen Bonding; Protein Conformation; Reverse Transcriptase Inhibitors; RNA-Directed DNA Polymerase; Structure-Activity Relationship | 1996 |
Estimation of binding affinities for HEPT and nevirapine analogues with HIV-1 reverse transcriptase via Monte Carlo simulations.
Topics: Anti-HIV Agents; HIV Reverse Transcriptase; Models, Molecular; Monte Carlo Method; Nevirapine; Protein Binding; Pyrimidinones; Regression Analysis; Reverse Transcriptase Inhibitors; Thermodynamics; Uracil | 2001 |
Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations.
Topics: Alkynes; Anilides; Benzoxazines; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nevirapine; Oxazines; Protein Binding; Quinoxalines; Regression Analysis; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil | 2002 |
Computer-aided design, synthesis, and anti-HIV-1 activity in vitro of 2-alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones as novel potent non-nucleoside reverse transcriptase inhibitors, also active against the Y181C varia
Topics: Cell Line; Computer Simulation; Drug Design; Drug Resistance, Viral; HIV Reverse Transcriptase; HIV-1; HIV-2; Humans; Models, Molecular; Mutation; Pyrimidinones; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors | 2004 |
Hierarchical database screenings for HIV-1 reverse transcriptase using a pharmacophore model, rigid docking, solvation docking, and MM-PB/SA.
Topics: Allosteric Site; Anti-HIV Agents; Crystallography, X-Ray; Databases, Factual; Drug Design; HIV Reverse Transcriptase; Models, Molecular; Molecular Conformation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Statistics as Topic; Thermodynamics | 2005 |
Synthesis and anti-HIV-1 activity of novel 2,3-dihydro-7H-thiazolo[3,2-a]pyrimidin-7-ones.
Topics: Alkylation; Anti-HIV Agents; Cell Line; HIV Reverse Transcriptase; HIV-1; Humans; Magnetic Resonance Spectroscopy; Mesylates; Pyrimidines; Pyrimidinones; Reverse Transcriptase Inhibitors; T-Lymphocytes; Thiazoles; Thymine; Uracil; Virus Replication | 1998 |