Compounds > 1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine
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1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine and 5-ethyl-1-benzyloxymethyl-6-(phenylthio)uracil

1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine has been researched along with 5-ethyl-1-benzyloxymethyl-6-(phenylthio)uracil in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (50.00)18.2507
2000's2 (33.33)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baba, M; De Clercq, E; Miyasaka, T; Nitta, I; Sekiya, K; Shigeta, S; Takashima, H; Tanaka, H; Ubasawa, M; Walker, RT1
Baba, M; Miyasaka, T; Nakashima, H; Nitta, I; Saito, S; Sekiya, K; Takashima, H; Tanaka, H; Ubasawa, M; Walker, RT1
Aubertin, AM; Benhida, R; Grierson, DS; Monneret, C; Pontikis, R1
Jorgensen, WL; Rizzo, RC; Tirado-Rives, J1
Jorgensen, WL; Kroeger Smith, MB; Rizzo, RC; Smith, RH; Tirado-Rives, J; Udier-Blagović, M; Wang, DP; Watkins, EK1
Miljković, FN; Toropov, AA; Toropova, AP; Veselinović, AM; Veselinović, JB1

Other Studies

6 other study(ies) available for 1-((2-hydroxyethoxy)methyl)-6-(phenylthio)thymine and 5-ethyl-1-benzyloxymethyl-6-(phenylthio)uracil

ArticleYear
Synthesis and antiviral activity of deoxy analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT) as potent and selective anti-HIV-1 agents.
    Journal of medicinal chemistry, 1992, Dec-11, Volume: 35, Issue:25

    Topics: Antiviral Agents; Cells, Cultured; HIV-1; Structure-Activity Relationship; Thymine; Virus Replication

1992
Specific anti-HIV-1 "acyclonucleosides" which cannot be phosphorylated: synthesis of some deoxy analogues of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:4

    Topics: Animals; Antiviral Agents; Cell Line; HIV-1; Humans; Molecular Structure; Structure-Activity Relationship; Thymine; Virus Replication

1991
Synthesis and anti-HIV activity of novel N-1 side chain-modified analogs of 1-[(2-hydroxyethoxy)methyl]-6-(phenylthio)thymine (HEPT).
    Journal of medicinal chemistry, 1997, Jun-06, Volume: 40, Issue:12

    Topics: Anti-HIV Agents; Enzyme Inhibitors; HIV Reverse Transcriptase; HIV-1; Molecular Structure; Structure-Activity Relationship; Uracil; Virus Replication

1997
Estimation of binding affinities for HEPT and nevirapine analogues with HIV-1 reverse transcriptase via Monte Carlo simulations.
    Journal of medicinal chemistry, 2001, Jan-18, Volume: 44, Issue:2

    Topics: Anti-HIV Agents; HIV Reverse Transcriptase; Models, Molecular; Monte Carlo Method; Nevirapine; Protein Binding; Pyrimidinones; Regression Analysis; Reverse Transcriptase Inhibitors; Thermodynamics; Uracil

2001
Prediction of activity for nonnucleoside inhibitors with HIV-1 reverse transcriptase based on Monte Carlo simulations.
    Journal of medicinal chemistry, 2002, Jul-04, Volume: 45, Issue:14

    Topics: Alkynes; Anilides; Benzoxazines; Computer Simulation; Cyclopropanes; HIV Reverse Transcriptase; Hydrogen Bonding; Models, Molecular; Monte Carlo Method; Nevirapine; Oxazines; Protein Binding; Quinoxalines; Regression Analysis; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Uracil

2002
QSAR models for HEPT derivates as NNRTI inhibitors based on Monte Carlo method.
    European journal of medicinal chemistry, 2014, Apr-22, Volume: 77

    Topics: Anti-HIV Agents; Computer-Aided Design; Dose-Response Relationship, Drug; Drug Design; HIV Reverse Transcriptase; Inhibitory Concentration 50; Molecular Structure; Monte Carlo Method; Quantitative Structure-Activity Relationship; Reverse Transcriptase Inhibitors; Thymine

2014