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(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide and sdz 205-557

(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide has been researched along with sdz 205-557 in 2 studies

Compound Research Comparison

Studies
((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide)
Trials
((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide)
Recent Studies (post-2010)
((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide)
Studies
(sdz 205-557)
Trials
(sdz 205-557)
Recent Studies (post-2010) (sdz 205-557)
24005609

Protein Interaction Comparison

ProteinTaxonomy(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide (IC50)sdz 205-557 (IC50)
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.2512
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.2512

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sanger, GJ; Wardle, KA1
Bartolini, A; Casamenti, F; Galeotti, N; Ghelardini, C; Gualtieri, F; Malmberg-Aiello, P; Pepeu, G1

Other Studies

2 other study(ies) available for (endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide and sdz 205-557

ArticleYear
The guinea-pig distal colon--a sensitive preparation for the investigation of 5-HT4 receptor-mediated contractions.
    British journal of pharmacology, 1993, Volume: 110, Issue:4

    Topics: 4-Aminobenzoic Acid; Animals; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Colon; Dose-Response Relationship, Drug; Granisetron; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; para-Aminobenzoates; Receptors, Serotonin; Serotonin

1993
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8.
    Life sciences, 1996, Volume: 58, Issue:25

    Topics: 4-Aminobenzoic Acid; Analgesics; Animals; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Indoles; Male; Mice; Organophosphorus Compounds; Pain Threshold; para-Aminobenzoates; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides

1996