(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide has been researched along with gr 113808 in 5 studies
| Studies ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Trials ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Recent Studies (post-2010) ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Studies (gr 113808) | Trials (gr 113808) | Recent Studies (post-2010) (gr 113808) |
|---|---|---|---|---|---|
| 24 | 0 | 0 | 165 | 1 | 35 |
| Protein | Taxonomy | (endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide (IC50) | gr 113808 (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 4 | Homo sapiens (human) | 0.0002 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bonhaus, DW; Eglen, RM; Jakeman, LB; To, ZP; Wong, EH | 1 |
| Contesse, V; Delarue, C; Hamel, C; Lefebvre, H; Vaudry, H | 1 |
| Arnaboldi, S; Consolo, S; Giorgi, S; Ladinsky, H; Russi, G | 1 |
| Bartolini, A; Casamenti, F; Galeotti, N; Ghelardini, C; Gualtieri, F; Malmberg-Aiello, P; Pepeu, G | 1 |
| Bartolini, A; Galeotti, N; Ghelardini, C | 1 |
5 other study(ies) available for (endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide and gr 113808
| Article | Year |
|---|---|
Quantitative autoradiography of 5-HT4 receptors in brains of three species using two structurally distinct radioligands, [3H]GR113808 and [3H]BIMU-1.
Topics: Animals; Autoradiography; Benzimidazoles; Brain; Brain Chemistry; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Guinea Pigs; Haloperidol; Indoles; Ligands; Macaca; Macaca nemestrina; Male; Rats; Rats, Sprague-Dawley; Receptors, Serotonin; Serotonin Antagonists; Species Specificity; Sulfonamides | 1994 |
Effect of a series of 5-HT4 receptor agonists and antagonists on steroid secretion by the adrenal gland in vitro.
Topics: Adrenal Glands; Aldosterone; Animals; Benzamides; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Corticosterone; Dose-Response Relationship, Drug; Indoles; Male; Radioligand Assay; Ranidae; Receptors, Serotonin; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Stereoisomerism; Structure-Activity Relationship; Sulfonamides; Tropisetron | 1994 |
5-HT4 receptor stimulation facilitates acetylcholine release in rat frontal cortex.
Topics: Acetylcholine; Animals; Benzimidazoles; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Female; Frontal Lobe; Indoles; Injections, Intraventricular; Microdialysis; Neostriatum; Rats; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 1994 |
Central cholinergic antinociception induced by 5HT4 agonists: BIMU 1 and BIMU 8.
Topics: 4-Aminobenzoic Acid; Analgesics; Animals; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Indoles; Male; Mice; Organophosphorus Compounds; Pain Threshold; para-Aminobenzoates; Rats; Rats, Wistar; Receptors, Cholinergic; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Serotonin Antagonists; Serotonin Receptor Agonists; Sulfonamides | 1996 |
Role of 5-HT4 receptors in the mouse passive avoidance test.
Topics: Amnesia; Animals; Avoidance Learning; Benzimidazoles; Bridged Bicyclo Compounds, Heterocyclic; Indoles; Male; Memory; Mice; Ondansetron; Receptors, Serotonin; Receptors, Serotonin, 5-HT4; Sulfonamides | 1998 |