(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide has been researched along with bemesetron in 2 studies
| Studies ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Trials ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Recent Studies (post-2010) ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Studies (bemesetron) | Trials (bemesetron) | Recent Studies (post-2010) (bemesetron) |
|---|---|---|---|---|---|
| 24 | 0 | 0 | 254 | 3 | 25 |
| Protein | Taxonomy | (endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide (IC50) | bemesetron (IC50) |
|---|---|---|---|
| 5-hydroxytryptamine receptor 3E | Homo sapiens (human) | 0.0093 | |
| 5-hydroxytryptamine receptor 3B | Homo sapiens (human) | 0.0093 | |
| 5-hydroxytryptamine receptor 3A | Rattus norvegicus (Norway rat) | 0.097 | |
| 5-hydroxytryptamine receptor 3A | Homo sapiens (human) | 0.0928 | |
| 5-hydroxytryptamine receptor 3D | Homo sapiens (human) | 0.0093 | |
| 5-hydroxytryptamine receptor 3C | Homo sapiens (human) | 0.0093 | |
| 5-hydroxytryptamine receptor 3B | Rattus norvegicus (Norway rat) | 0.097 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Donetti, A; Giraldo, E; Maiocchi, L; Micheletti, R; Nicola, M; Quintero, MG; Turconi, M | 1 |
| Childers, SR; Mach, RH; West, T; Whirrett, BR; Wu, L | 1 |
2 other study(ies) available for (endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide and bemesetron
| Article | Year |
|---|---|
Synthesis of a new class of 2,3-dihydro-2-oxo-1H-benzimidazole-1-carboxylic acid derivatives as highly potent 5-HT3 receptor antagonists.
Topics: Animals; Benzimidazoles; Binding, Competitive; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Cerebral Cortex; Chemical Phenomena; Chemistry; Computer Simulation; Hydrogen Bonding; Indoles; Models, Molecular; Molecular Structure; Radioligand Assay; Rats; Receptors, Serotonin; Reflex; Serotonin Antagonists; Structure-Activity Relationship; Tropisetron | 1990 |
The analgesic tropane analogue (+/-)-SM 21 has a high affinity for sigma2 receptors.
Topics: Analgesics; Animals; Atropine; Benzimidazoles; Benztropine; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Butyrates; Guinea Pigs; In Vitro Techniques; Ligands; Muscarinic Antagonists; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Receptors, sigma; Serotonin Antagonists; Sigma-1 Receptor; Structure-Activity Relationship; Tropanes | 1999 |