(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide has been researched along with atropine in 1 studies
Studies ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Trials ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Recent Studies (post-2010) ((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide) | Studies (atropine) | Trials (atropine) | Recent Studies (post-2010) (atropine) |
---|---|---|---|---|---|
24 | 0 | 0 | 26,711 | 1,259 | 1,697 |
Protein | Taxonomy | (endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide (IC50) | atropine (IC50) |
---|---|---|---|
cystic fibrosis transmembrane conductance regulator | Homo sapiens (human) | 21.41 | |
5-hydroxytryptamine receptor 4 | Cavia porcellus (domestic guinea pig) | 1.012 | |
Muscarinic acetylcholine receptor M2 | Homo sapiens (human) | 0.0067 | |
Muscarinic acetylcholine receptor M4 | Homo sapiens (human) | 0.0007 | |
Muscarinic acetylcholine receptor M1 | Rattus norvegicus (Norway rat) | 0.001 | |
Muscarinic acetylcholine receptor M3 | Rattus norvegicus (Norway rat) | 0.001 | |
Muscarinic acetylcholine receptor M4 | Rattus norvegicus (Norway rat) | 0.001 | |
Muscarinic acetylcholine receptor M5 | Rattus norvegicus (Norway rat) | 0.001 | |
Muscarinic acetylcholine receptor M5 | Homo sapiens (human) | 0.0009 | |
Muscarinic acetylcholine receptor M2 | Rattus norvegicus (Norway rat) | 0.001 | |
Muscarinic acetylcholine receptor M1 | Homo sapiens (human) | 0.0015 | |
Muscarinic acetylcholine receptor M3 | Homo sapiens (human) | 0.0021 | |
Alpha-1D adrenergic receptor | Homo sapiens (human) | 1.354 | |
5-hydroxytryptamine receptor 2C | Homo sapiens (human) | 1.012 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (100.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Childers, SR; Mach, RH; West, T; Whirrett, BR; Wu, L | 1 |
1 other study(ies) available for (endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide and atropine
Article | Year |
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The analgesic tropane analogue (+/-)-SM 21 has a high affinity for sigma2 receptors.
Topics: Analgesics; Animals; Atropine; Benzimidazoles; Benztropine; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Butyrates; Guinea Pigs; In Vitro Techniques; Ligands; Muscarinic Antagonists; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Receptors, sigma; Serotonin Antagonists; Sigma-1 Receptor; Structure-Activity Relationship; Tropanes | 1999 |