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(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide and atropine

(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide has been researched along with atropine in 1 studies

Compound Research Comparison

Studies
((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide)
Trials
((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide)
Recent Studies (post-2010)
((endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide)
Studies
(atropine)
Trials
(atropine)
Recent Studies (post-2010) (atropine)
240026,7111,2591,697

Protein Interaction Comparison

ProteinTaxonomy(endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide (IC50)atropine (IC50)
cystic fibrosis transmembrane conductance regulatorHomo sapiens (human)21.41
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)1.012
Muscarinic acetylcholine receptor M2Homo sapiens (human)0.0067
Muscarinic acetylcholine receptor M4Homo sapiens (human)0.0007
Muscarinic acetylcholine receptor M1Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M3Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M4Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M5Homo sapiens (human)0.0009
Muscarinic acetylcholine receptor M2Rattus norvegicus (Norway rat)0.001
Muscarinic acetylcholine receptor M1Homo sapiens (human)0.0015
Muscarinic acetylcholine receptor M3Homo sapiens (human)0.0021
Alpha-1D adrenergic receptorHomo sapiens (human)1.354
5-hydroxytryptamine receptor 2CHomo sapiens (human)1.012

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Childers, SR; Mach, RH; West, T; Whirrett, BR; Wu, L1

Other Studies

1 other study(ies) available for (endo-n-8-methyl-8-azabicyclo(3.2.1)oct-3-yl)-2,3-dihydro-3-ethyl-2-oxo-1h-benzimidazol-1-carboxamide and atropine

ArticleYear
The analgesic tropane analogue (+/-)-SM 21 has a high affinity for sigma2 receptors.
    Life sciences, 1999, Volume: 64, Issue:10

    Topics: Analgesics; Animals; Atropine; Benzimidazoles; Benztropine; Binding, Competitive; Brain; Bridged Bicyclo Compounds, Heterocyclic; Butyrates; Guinea Pigs; In Vitro Techniques; Ligands; Muscarinic Antagonists; Rats; Receptors, Serotonin; Receptors, Serotonin, 5-HT3; Receptors, Serotonin, 5-HT4; Receptors, sigma; Serotonin Antagonists; Sigma-1 Receptor; Structure-Activity Relationship; Tropanes

1999