(e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide has been researched along with n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide in 4 studies
| Studies ((e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide) | Trials ((e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide) | Recent Studies (post-2010) ((e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide) | Studies (n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide) | Trials (n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide) | Recent Studies (post-2010) (n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide) |
|---|---|---|---|---|---|
| 85 | 0 | 65 | 83 | 1 | 48 |
| Protein | Taxonomy | (e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide (IC50) | n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide (IC50) |
|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | Rattus norvegicus (Norway rat) | 0.0051 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.0004 | |
| Potassium voltage-gated channel subfamily H member 2 | Homo sapiens (human) | 1 | |
| Transient receptor potential cation channel subfamily M member 8 | Homo sapiens (human) | 0.6375 | |
| Transient receptor potential cation channel subfamily V member 1 | Homo sapiens (human) | 0.0119 | |
| Transient receptor potential cation channel subfamily M member 8 | Rattus norvegicus (Norway rat) | 0.475 | |
| Transient receptor potential cation channel subfamily M member 8 | Mus musculus (house mouse) | 0.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Westaway, SM | 1 |
| Brennan, FX; Bryant, RW; Devantier, HR; Long, DJ; Palmer, RK; Salemme, FR | 1 |
| Bölcskei, K; Dézsi, L; Horváth, C; Kis-Varga, A; Petho, G; Szentirmay, E; Szolcsányi, J; Tékus, V; Visegrády, A | 1 |
| Ide, S; Kojima, S; Nakanishi, Y; Nishino, K; Tanamachi, K; Tanuma, S; Tsukimoto, M | 1 |
1 review(s) available for (e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide and n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide
| Article | Year |
|---|---|
The potential of transient receptor potential vanilloid type 1 channel modulators for the treatment of pain.
Topics: Analgesics; Animals; Capsaicin; Humans; Pain; TRPV Cation Channels | 2007 |
3 other study(ies) available for (e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide and n-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2h)-carboxamide
| Article | Year |
|---|---|
Pharmacologic antagonism of the oral aversive taste-directed response to capsaicin in a mouse brief access taste aversion assay.
Topics: Acrylamides; Administration, Oral; Alkaloids; Anilides; Animals; Avoidance Learning; Benzodioxoles; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cinnamates; Diterpenes; Dose-Response Relationship, Drug; Female; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Piperidines; Polyunsaturated Alkamides; Pyrazines; Pyridines; Taste; TRPM Cation Channels; TRPV Cation Channels | 2010 |
Effect of transient receptor potential vanilloid 1 (TRPV1) receptor antagonist compounds SB705498, BCTC and AMG9810 in rat models of thermal hyperalgesia measured with an increasing-temperature water bath.
Topics: Acrylamides; Animals; Bridged Bicyclo Compounds, Heterocyclic; Cold Temperature; Disease Models, Animal; Diterpenes; Dose-Response Relationship, Drug; Female; Hot Temperature; Hyperalgesia; Pain; Pyrazines; Pyridines; Pyrrolidines; Rats; Rats, Sprague-Dawley; TRPV Cation Channels; Urea | 2010 |
Radiosensitizing Effect of TRPV1 Channel Inhibitors in Cancer Cells.
Topics: Acrylamides; Anilides; Animals; Apoptosis; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Cell Line, Tumor; Cell Survival; Cinnamates; DNA Damage; Gamma Rays; Humans; Mice; Necrosis; Neoplasms; Pyrazines; Pyridines; Radiation-Sensitizing Agents; TRPV Cation Channels | 2016 |