(e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide has been researched along with amiloride in 3 studies
| Studies ((e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide) | Trials ((e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide) | Recent Studies (post-2010) ((e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide) | Studies (amiloride) | Trials (amiloride) | Recent Studies (post-2010) (amiloride) |
|---|---|---|---|---|---|
| 85 | 0 | 65 | 7,584 | 339 | 788 |
| Protein | Taxonomy | (e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide (IC50) | amiloride (IC50) |
|---|---|---|---|
| Urokinase-type plasminogen activator | Homo sapiens (human) | 4.7 | |
| Urokinase-type plasminogen activator | Mus musculus (house mouse) | 2.3 | |
| Amine oxidase [flavin-containing] A | Homo sapiens (human) | 3.909 | |
| Sodium/hydrogen exchanger 1 | Rattus norvegicus (Norway rat) | 1 | |
| Amiloride-sensitive sodium channel subunit alpha | Homo sapiens (human) | 0.776 | |
| Sodium/hydrogen exchanger 2 | Oryctolagus cuniculus (rabbit) | 1 | |
| Acid-sensing ion channel 3 | Homo sapiens (human) | 4.4 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, Y; Yu, S; Yu, X | 1 |
| Hummel, M; Knappenberger, T; Reilly, M; Whiteside, GT | 1 |
| Fu, X; Huang, L; Lu, Z; Wang, X; Wang, Y; Xiao, Z; Zhu, F | 1 |
3 other study(ies) available for (e)-3-(4-t-butylphenyl)-n-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide and amiloride
| Article | Year |
|---|---|
Effects of acid on vagal nociceptive afferent subtypes in guinea pig esophagus.
Topics: Acids; Acrylamides; Action Potentials; Amiloride; Animals; Bridged Bicyclo Compounds, Heterocyclic; Capsaicin; Esophagus; Guinea Pigs; Heartburn; In Vitro Techniques; Male; Nerve Fibers, Unmyelinated; Nociception; Nodose Ganglion; TRPV Cation Channels; Vagus Nerve | 2014 |
Pharmacological evaluation of NSAID-induced gastropathy as a "Translatable" model of referred visceral hypersensitivity.
Topics: Acetanilides; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acrylamides; Amiloride; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Bridged Bicyclo Compounds, Heterocyclic; Disease Models, Animal; Drug Evaluation, Preclinical; Humans; Hyperalgesia; Male; Mice; Morphine; Pain Measurement; Purines; Random Allocation; Receptors, Atrial Natriuretic Factor; Receptors, Opioid; Stomach Ulcer; Transient Receptor Potential Channels; Visceral Pain | 2017 |
Increased Asics Expression via the Camkii-CREB Pathway in a Novel Mouse Model of Trigeminal Pain.
Topics: Acetic Acid; Acid Sensing Ion Channel Blockers; Acid Sensing Ion Channels; Acrylamides; Amiloride; Animals; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; Calcitonin Gene-Related Peptide; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Pain; Phosphorylation; Proto-Oncogene Proteins c-fos; Trigeminal Nucleus, Spinal; TRPV Cation Channels | 2018 |