Page last updated: 2024-09-02

(S)-Mephenytoin and omeprazole

(S)-Mephenytoin has been researched along with omeprazole in 2 studies

Compound Research Comparison

Studies ((S)-Mephenytoin)	Trials ((S)-Mephenytoin)	Recent Studies (post-2010) ((S)-Mephenytoin)	Studies (omeprazole)	Trials (omeprazole)	Recent Studies (post-2010) (omeprazole)
13	0	11	9,085	2,737	1,487

Protein Interaction Comparison

Protein	Taxonomy	omeprazole (IC50)
Mcl-1	Homo sapiens (human)	3.1448
cGMP-specific 3',5'-cyclic phosphodiesterase	Homo sapiens (human)	0.28
Potassium-transporting ATPase alpha chain 1	Homo sapiens (human)	1.45
Cytochrome P450 2C19	Homo sapiens (human)	2.315
Potassium-transporting ATPase subunit beta	Homo sapiens (human)	1.45
WD repeat-containing protein 5	Homo sapiens (human)	1.7
Glutathione S-transferase omega-1	Homo sapiens (human)	4.6
Histone-lysine N-methyltransferase 2A	Homo sapiens (human)	1.7
Muscarinic acetylcholine receptor	Cavia porcellus (domestic guinea pig)	3.8

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dai, R; Liu, Y; She, M; Wu, Z	1
An, N; Bian, T; Chen, C; Gao, Y; Liu, D; Wang, H; Zhu, J	1

Other Studies

2 other study(ies) available for (S)-Mephenytoin and omeprazole

Article	Year
The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors. Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:3 Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity	2011
Evaluation of the effects of 20 nonsynonymous single nucleotide polymorphisms of CYP2C19 on S-mephenytoin 4'-hydroxylation and omeprazole 5'-hydroxylation. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5 Topics: Anticonvulsants; Apoproteins; Aryl Hydrocarbon Hydroxylases; Computer Simulation; Cytochrome P-450 CYP2C19; Enzyme Inhibitors; Humans; Hydroxylation; Mephenytoin; Microsomes, Liver; Models, Molecular; Omeprazole; Polymorphism, Single Nucleotide; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Software; Structure-Activity Relationship; Substrate Specificity	2011

Article

Year

The inhibition study of human UDP-glucuronosyltransferases with cytochrome P450 selective substrates and inhibitors.

Journal of enzyme inhibition and medicinal chemistry, 2011, Volume: 26, Issue:3

Topics: Cytochrome P-450 Enzyme Inhibitors; Enzyme Activation; Enzyme Inhibitors; Glucuronosyltransferase; Humans; Molecular Structure; Recombinant Proteins; Stereoisomerism; Structure-Activity Relationship; Substrate Specificity

2011

Evaluation of the effects of 20 nonsynonymous single nucleotide polymorphisms of CYP2C19 on S-mephenytoin 4'-hydroxylation and omeprazole 5'-hydroxylation.

Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5

Topics: Anticonvulsants; Apoproteins; Aryl Hydrocarbon Hydroxylases; Computer Simulation; Cytochrome P-450 CYP2C19; Enzyme Inhibitors; Humans; Hydroxylation; Mephenytoin; Microsomes, Liver; Models, Molecular; Omeprazole; Polymorphism, Single Nucleotide; Protein Conformation; Recombinant Proteins; Saccharomyces cerevisiae; Software; Structure-Activity Relationship; Substrate Specificity

2011