Compounds > (S)-Mephenytoin
Page last updated: 2024-09-02

(S)-Mephenytoin and amiodarone

(S)-Mephenytoin has been researched along with amiodarone in 1 studies

Compound Research Comparison

Studies
((S)-Mephenytoin)		Trials
((S)-Mephenytoin)		Recent Studies (post-2010)
((S)-Mephenytoin)		Studies
(amiodarone)		Trials
(amiodarone)		Recent Studies (post-2010) (amiodarone)
130118,1567431,889

Protein Interaction Comparison

ProteinTaxonomy(S)-Mephenytoin (IC50)amiodarone (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.27
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.085
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.404
Bile salt export pumpHomo sapiens (human)10
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)9.148
Tyrosine-protein kinase FynHomo sapiens (human)0.817
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)2.271
Muscarinic acetylcholine receptor M2Homo sapiens (human)5.08
Muscarinic acetylcholine receptor M4Homo sapiens (human)3.63
Muscarinic acetylcholine receptor M5Homo sapiens (human)1.499
Alpha-2A adrenergic receptorHomo sapiens (human)0.312
Thyroid hormone receptor alphaHomo sapiens (human)0.65
Thyroid hormone receptor betaHomo sapiens (human)0.6
Muscarinic acetylcholine receptor M1Homo sapiens (human)2.613
Lethal factorBacillus anthracis3.5
Muscarinic acetylcholine receptor M3Homo sapiens (human)3.201
D(1A) dopamine receptorHomo sapiens (human)9.142
Sodium-dependent noradrenaline transporter Homo sapiens (human)2.271
5-hydroxytryptamine receptor 2AHomo sapiens (human)3.59
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.404
Sodium-dependent serotonin transporterHomo sapiens (human)2.305
Melanocortin receptor 5Homo sapiens (human)9.497
D(3) dopamine receptorHomo sapiens (human)1.208
Sodium channel protein type 1 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 4 subunit alphaHomo sapiens (human)4.8
Squalene synthaseHomo sapiens (human)8
Delta-type opioid receptorHomo sapiens (human)8.014
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.923
Sodium channel protein type 7 subunit alphaHomo sapiens (human)4.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.085
Sodium-dependent dopamine transporter Homo sapiens (human)2.505
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)6.206
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.085
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.085
Sodium channel protein type 5 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 9 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 2 subunit alphaHomo sapiens (human)4.8
Sigma non-opioid intracellular receptor 1Homo sapiens (human)0.097
Sodium channel protein type 3 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 11 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 8 subunit alphaHomo sapiens (human)4.8
Sodium channel protein type 10 subunit alphaHomo sapiens (human)4.8

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Belas, F; Chaudhary, AK; Cvetkovic, M; Dempsey, PJ; Fromm, MF; Kim, RB; Leake, B; Roden, DM; Roden, MM; Wandel, C; Wilkinson, GR; Wood, AJ1

Other Studies

1 other study(ies) available for (S)-Mephenytoin and amiodarone

ArticleYear
Interrelationship between substrates and inhibitors of human CYP3A and P-glycoprotein.
    Pharmaceutical research, 1999, Volume: 16, Issue:3

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cells, Cultured; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Resistance, Multiple; Enzyme Inhibitors; Humans; Male; Mice; Oxidoreductases, N-Demethylating; Pharmacokinetics; Substrate Specificity

1999