(8)-shogaol and gingerol

(8)-shogaol has been researched along with gingerol* in 2 studies

Other Studies

2 other study(ies) available for (8)-shogaol and gingerol

Article	Year
Formation of 6-, 8- and 10-Shogaol in Ginger through Application of Different Drying Methods: Altered Antioxidant and Antimicrobial Activity. Molecules (Basel, Switzerland), 2018, 07-05, Volume: 23, Issue:7 Topics: Anti-Infective Agents; Antioxidants; Catechols; Chromatography, High Pressure Liquid; Desiccation; Fatty Alcohols; Gram-Negative Bacteria; Gram-Positive Bacteria; Guaiacol; Microbial Sensitivity Tests; Oils, Volatile; Plant Extracts; Plant Oils; Zingiber officinale	2018
Identification of serotonin 5-HT1A receptor partial agonists in ginger. Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9 Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the human serotonin 5-HT(1A) receptor with significant to moderate binding affinities (K(i)=3-20 microM). [(35)S]-GTP gamma S assays indicated that 10-shogaol, 1-dehydro-6-gingerdione, and particularly the whole lipophilic ginger extract (K(i)=11.6 microg/ml) partially activate the 5-HT(1A) receptor (20-60% of maximal activation). In addition, the intestinal absorption of gingerols and shogaols was simulated and their interactions with P-glycoprotein were measured, suggesting a favourable pharmacokinetic profile for the 5-HT(1A) active compounds. Topics: Anti-Anxiety Agents; Caco-2 Cells; Catechols; Cell Line; Fatty Alcohols; Humans; Molecular Structure; Serotonin 5-HT1 Receptor Agonists; Zingiber officinale	2010

Article

Year

Formation of 6-, 8- and 10-Shogaol in Ginger through Application of Different Drying Methods: Altered Antioxidant and Antimicrobial Activity.

Molecules (Basel, Switzerland), 2018, 07-05, Volume: 23, Issue:7

Topics: Anti-Infective Agents; Antioxidants; Catechols; Chromatography, High Pressure Liquid; Desiccation; Fatty Alcohols; Gram-Negative Bacteria; Gram-Positive Bacteria; Guaiacol; Microbial Sensitivity Tests; Oils, Volatile; Plant Extracts; Plant Oils; Zingiber officinale

2018

Identification of serotonin 5-HT1A receptor partial agonists in ginger.

Bioorganic & medicinal chemistry, 2010, May-01, Volume: 18, Issue:9

Animal studies suggest that ginger (Zingiber officinale Roscoe) reduces anxiety. In this study, bioactivity-guided fractionation of a ginger extract identified nine compounds that interact with the human serotonin 5-HT(1A) receptor with significant to moderate binding affinities (K(i)=3-20 microM). [(35)S]-GTP gamma S assays indicated that 10-shogaol, 1-dehydro-6-gingerdione, and particularly the whole lipophilic ginger extract (K(i)=11.6 microg/ml) partially activate the 5-HT(1A) receptor (20-60% of maximal activation). In addition, the intestinal absorption of gingerols and shogaols was simulated and their interactions with P-glycoprotein were measured, suggesting a favourable pharmacokinetic profile for the 5-HT(1A) active compounds.

Topics: Anti-Anxiety Agents; Caco-2 Cells; Catechols; Cell Line; Fatty Alcohols; Humans; Molecular Structure; Serotonin 5-HT1 Receptor Agonists; Zingiber officinale

2010