Compounds > (3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone
Page last updated: 2024-08-16

(3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone and hu 210

(3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone has been researched along with hu 210 in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (16.67)18.2507
2000's4 (33.33)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Blond, O; Briley, EM; Felder, CC; Joyce, KE; Lai, Y; Ma, AL; Mackie, K; Mansouri, J; Mitchell, RL1
Abood, ME; Compton, DR; Martin, BR; Showalter, VM1
Chavatte, P; Depreux, P; Farce, A; Goossens, JF; Hénichart, JP; Lambert, DM; Millet, R; Muccioli, GG; Poupaert, JH; Stern, E1
Charlier, C; De Martino, P; Di Pace, P; Lambert, DM; Muccioli, GG; Pizza, T; Poppitz, W; Poupaert, JH; Scriba, GK; Wouters, J1
Allarà, M; Benetti, V; Cascio, MG; Di Marzo, V; Ferrarini, PL; Ghelardini, C; Manera, C; Martinelli, A; Saccomanni, G; Tuccinardi, T; Vivoli, E1
Brizzi, A; Brizzi, V; Cascio, MG; Corelli, F; Di Marzo, V; Guida, F; Ligresti, A; Maione, S; Martinelli, A; Pasquini, S; Tuccinardi, T1
Balansa, W; Capon, RJ; Fontaine, F; Gilbert, DF; Islam, R; Lynch, JW; Piggott, AM; Webb, TI; Zhang, H1
Buzard, DJ; Han, S; Jones, RM; Thatte, J1
Brust, P; Günther, R; Lueg, C; Schepmann, D; Wünsch, B1
Aiello, F; Brizzi, A; Brizzi, V; Cascio, MG; Corelli, F; De Petrocellis, L; Di Marzo, V; Lamponi, S; Ligresti, A; Luongo, L; Maione, S; Marini, P; Pertwee, RG1
de Vries, H; Frehland, B; Heimann, D; Heitman, LH; Lueg, C; Schepmann, D; Wünsch, B1
Aiello, F; Boccella, S; Brizzi, A; Cascio, MG; Corelli, F; De Petrocellis, L; Di Marzo, V; Frosini, M; Gado, F; Ligresti, A; Luongo, L; Maione, S; Manera, C; Marini, P; Mugnaini, C; Pertwee, RG; Pessina, F1

Reviews

1 review(s) available for (3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone and hu 210

ArticleYear
Therapeutic utility of cannabinoid receptor type 2 (CB(2)) selective agonists.
    Journal of medicinal chemistry, 2013, Nov-14, Volume: 56, Issue:21

    Topics: Animals; Drug Design; Humans; Ligands; Models, Molecular; Molecular Conformation; Receptor, Cannabinoid, CB2; Structure-Activity Relationship; Substrate Specificity

2013

Other Studies

11 other study(ies) available for (3r)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone and hu 210

ArticleYear
Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.
    Molecular pharmacology, 1995, Volume: 48, Issue:3

    Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Amidohydrolases; Animals; Arachidonic Acids; Base Sequence; Binding, Competitive; Calcium; Calcium Channel Blockers; Cannabinoids; CHO Cells; Cricetinae; Endocannabinoids; Enzyme Activation; Humans; Intracellular Fluid; Ion Channels; Kinetics; Mice; Molecular Sequence Data; Phospholipases; Polyunsaturated Alkamides; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Signal Transduction; Transfection

1995
Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands.
    The Journal of pharmacology and experimental therapeutics, 1996, Volume: 278, Issue:3

    Topics: Animals; Binding, Competitive; Brain; Cannabinoids; Cell Membrane; Cells, Cultured; CHO Cells; Cricetinae; Cyclohexanols; Guanine Nucleotides; Humans; Ligands; Rats; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Recombinant Proteins; Sodium; Structure-Activity Relationship; Transfection

1996
Novel 4-oxo-1,4-dihydroquinoline-3-carboxamide derivatives as new CB2 cannabinoid receptors agonists: synthesis, pharmacological properties and molecular modeling.
    Journal of medicinal chemistry, 2006, Jan-12, Volume: 49, Issue:1

    Topics: Crystallography, X-Ray; Humans; Models, Molecular; Molecular Structure; Quinolones; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Structure-Activity Relationship

2006
Synthesis and activity of 1,3,5-triphenylimidazolidine-2,4-diones and 1,3,5-triphenyl-2-thioxoimidazolidin-4-ones: characterization of new CB1 cannabinoid receptor inverse agonists/antagonists.
    Journal of medicinal chemistry, 2006, Feb-09, Volume: 49, Issue:3

    Topics: Amidohydrolases; Animals; Binding Sites; Binding, Competitive; Brain; CHO Cells; Cricetinae; Cricetulus; Crystallography, X-Ray; Humans; Imidazolidines; Imidazolines; In Vitro Techniques; Male; Models, Molecular; Radioligand Assay; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Stereoisomerism; Structure-Activity Relationship

2006
New 1,8-naphthyridine and quinoline derivatives as CB2 selective agonists.
    Bioorganic & medicinal chemistry letters, 2007, Dec-01, Volume: 17, Issue:23

    Topics: Animals; Cell Line; Humans; Mice; Naphthyridines; Pain Measurement; Quinolines; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2

2007
New resorcinol-anandamide "hybrids" as potent cannabinoid receptor ligands endowed with antinociceptive activity in vivo.
    Journal of medicinal chemistry, 2009, Apr-23, Volume: 52, Issue:8

    Topics: Analgesics; Animals; Arachidonic Acids; Cannabinoid Receptor Agonists; Cannabinoid Receptor Antagonists; Chlorocebus aethiops; COS Cells; Drug Partial Agonism; Endocannabinoids; Humans; Ligands; Mice; Models, Molecular; Pain Measurement; Phenols; Polyunsaturated Alkamides; Radioligand Assay; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Resorcinols; Stereotyped Behavior; Structure-Activity Relationship

2009
Ircinialactams: subunit-selective glycine receptor modulators from Australian sponges of the family Irciniidae.
    Bioorganic & medicinal chemistry, 2010, Apr-15, Volume: 18, Issue:8

    Topics: Animals; Australia; Cell Line; Humans; Indole Alkaloids; Lactams; Porifera; Protein Isoforms; Receptors, Glycine; Structure-Activity Relationship

2010
Development of fluorinated CB(2) receptor agonists for PET studies.
    Bioorganic & medicinal chemistry, 2013, Dec-01, Volume: 21, Issue:23

    Topics: Animals; Carbazoles; CHO Cells; Cricetulus; Halogenation; Humans; Ligands; Molecular Docking Simulation; Positron-Emission Tomography; Receptor, Cannabinoid, CB2; Structure-Activity Relationship

2013
Structure-affinity relationships and pharmacological characterization of new alkyl-resorcinol cannabinoid receptor ligands: Identification of a dual cannabinoid receptor/TRPA1 channel agonist.
    Bioorganic & medicinal chemistry, 2014, Sep-01, Volume: 22, Issue:17

    Topics: Analgesics; Animals; Calcium Channels; Cell Survival; Cells, Cultured; CHO Cells; Cricetulus; Dose-Response Relationship, Drug; Humans; Ligands; Male; Mice; Molecular Structure; Nerve Tissue Proteins; NIH 3T3 Cells; Nociception; Pain; Pain Measurement; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Resorcinols; Structure-Activity Relationship; Transient Receptor Potential Channels; TRPA1 Cation Channel

2014
Bioisosteric replacement of central 1,2,4-oxadiazole ring of high affinity CB
    MedChemComm, 2017, Aug-01, Volume: 8, Issue:8

    Topics:

2017
Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity.
    Bioorganic & medicinal chemistry, 2020, 06-01, Volume: 28, Issue:11

    Topics: Amides; Analgesics; Animals; Cell Line; Dose-Response Relationship, Drug; Humans; Male; Mice; Molecular Structure; Rats; Receptors, Cannabinoid; Resorcinols; Structure-Activity Relationship; TRPV Cation Channels

2020