(3h)2-carbomethoxy-3-(4-fluorophenyl)tropane has been researched along with vanoxerine in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (48.00) | 18.2507 |
| 2000's | 11 (44.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuhar, MJ; Pögün, S; Scheffel, U | 1 |
| Coffey, LL; Reith, ME; Xu, C | 1 |
| Dutta, AK; Madras, BK; Meltzer, PC; Reith, ME | 1 |
| Butler, T; Dobbie, JW; Duffield, R; Hjelle, JT; Ho, AK; Miller-Hjelle, MA; Reith, M; Steidley, KR | 1 |
| Chen, NH; Coffey, LL; Reith, ME; Xu, C | 1 |
| Coffey, LL; Dutta, AK; Reith, ME | 1 |
| Izenwasser, S; Kunko, PM; Loeloff, RJ | 1 |
| Geter-Douglass, B; Tirelli, E; Witkin, JM | 1 |
| Dutta, AK; Reith, ME; Xu, C | 1 |
| Berger, R; Brust, P; Hoepping, A; Johannsen, B; Leibnitz, P; Machill, S; Scheller, D; Spies, H | 1 |
| Dannals, RF; Matecka, D; Rice, KC; Rothman, RB; Villemagne, VL; Wong, DF; Yokoi, F | 1 |
| Harada, N; Kakiuchi, T; Nakanishi, S; Nishiyama, S; Ohba, H; Sato, K; Tsukada, H | 1 |
| Davidson, C; Douglas, SB; Ellinwood, EH; Lee, TH | 1 |
| Harada, N; Kakiuchi, T; Nishiyama, S; Ohba, H; Tsukada, H | 1 |
| Dutta, AK; Madras, BK; Reith, ME | 1 |
| Cao, J; Husbands, SM; Katz, JL; Kopajtic, T; Newman, AH | 1 |
| Schenk, S | 1 |
| Fukumoto, D; Harada, N; Kakiuchi, T; Nishiyama, S; Satoh, K; Tsukada, H | 1 |
| Chen, N; Reith, ME; Zhen, J | 1 |
| Chen, N; Dutta, AK; Maiti, S; Reith, ME; Zhen, J | 1 |
| Fagerholm, V; Grönroos, T; Haaparanta, M; Koivula, T; Lipponen, T; Marjamäki, P; Perhola, O; Solin, O; Vepsäläinen, J | 1 |
| Aksenov, MY; Aksenova, MV; Booze, RM; Mactutus, CF; Silvers, JM | 1 |
| Chen, N; Dutta, AK; Kharkar, P; Mishra, M; Reith, ME; Schmitt, KC; Zhen, J | 1 |
| Donovan, DM; Katz, JL; Kopajtic, TA; Liu, Y; Newman, AH; Surratt, CK | 1 |
| Huang, X; Midde, NM; Quizon, PM; Sun, WL; Yuan, Y; Zhan, CG; Zhu, J | 1 |
25 other study(ies) available for (3h)2-carbomethoxy-3-(4-fluorophenyl)tropane and vanoxerine
| Article | Year |
|---|---|
Cocaine displaces [3H]WIN 35,428 binding to dopamine uptake sites in vivo more rapidly than mazindol or GBR 12909.
Topics: Animals; Binding Sites; Binding, Competitive; Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Injections, Intravenous; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Mice; Nerve Tissue Proteins; Piperazines; Radioimmunoassay; Receptors, Drug | 1991 |
Translocation of dopamine and binding of 2 beta-carbomethoxy-3 beta-(4-fluorophenyl) tropane (WIN 35,428) measured under identical conditions in rat striatal synaptosomal preparations. Inhibition by various blockers.
Topics: Animals; Binding, Competitive; Carrier Proteins; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats; Rats, Sprague-Dawley; Synaptosomes; Tritium | 1995 |
O-526, a piperidine analog of GBR 12909, retains high affinity for the dopamine transporter in monkey caudate-putamen.
Topics: Animals; Carrier Proteins; Caudate Nucleus; Citalopram; Cocaine; Dopamine Plasma Membrane Transport Proteins; In Vitro Techniques; Macaca fascicularis; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Neurotransmitter Uptake Inhibitors; Piperazines; Piperidines; Protein Binding; Putamen; Serotonin; Serotonin Plasma Membrane Transport Proteins | 1994 |
Multiple drug classes and hyperosmolarity alter binding of muscarinic drugs to mesothelial cells in vitro.
Topics: Animals; Atropine; Cells, Cultured; Cocaine; Cycloheximide; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Epithelium; Mannitol; Muscarinic Antagonists; N-Methylscopolamine; Osmolar Concentration; Parasympatholytics; Peritoneum; Piperazines; Quinuclidinyl Benzilate; Rabbits; Receptors, Muscarinic; Scopolamine Derivatives; Sodium Chloride | 1995 |
[3H]WIN 35,428 [2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] binding to rat brain membranes. Comparing dopamine cell body areas with nerve terminal regions.
Topics: Animals; Brain; Cell Membrane; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Kinetics; Male; Mesencephalon; Nerve Endings; Nucleus Accumbens; Piperazines; Radioligand Assay; Rats; Rats, Sprague-Dawley; Tritium | 1996 |
Highly selective, novel analogs of 4-[2-(diphenylmethoxy)ethyl]- 1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity and selectivity.
Topics: Animals; Carrier Proteins; Citalopram; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rats | 1997 |
Chronic administration of the selective dopamine uptake inhibitor GBR 12,909, but not cocaine, produces marked decreases in dopamine transporter density.
Topics: Animals; Brain; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Male; Piperazines; Rats; Rats, Sprague-Dawley | 1997 |
gamma-Aminobutyric acidA agonists differentially augment gnawing induced by indirect-acting dopamine agonists in C57BL/6J mice.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Dopamine Agonists; GABA-A Receptor Agonists; Isoxazoles; Male; Mice; Mice, Inbred C57BL; Muscimol; Piperazines | 1998 |
Tolerance in the replacement of the benzhydrylic O atom in 4-[2-(diphenylmethoxy)ethyl]-1-benzylpiperidine derivatives by an N atom: development of new-generation potent and selective N-analogue molecules for the dopamine transporter.
Topics: Animals; Carrier Proteins; Cell Line; Citalopram; Cloning, Molecular; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Design; Humans; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Structure; Nerve Tissue Proteins; Piperazines; Piperidines; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Serotonin; Serotonin Plasma Membrane Transport Proteins; Structure-Activity Relationship; Transfection | 1998 |
Novel rhenium complexes derived from alpha-tropanol as potential ligands for the dopamine transporter.
Topics: Carrier Proteins; Chromatography, High Pressure Liquid; Cocaine; Crystallography, X-Ray; Dopamine Plasma Membrane Transport Proteins; Humans; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Piperazines; Rhenium; Structure-Activity Relationship; Tropanes | 1998 |
Doses of GBR12909 that suppress cocaine self-administration in non-human primates substantially occupy dopamine transporters as measured by [11C] WIN35,428 PET scans.
Topics: Animals; Carbon Radioisotopes; Carrier Proteins; Cocaine; Depression, Chemical; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Infusions, Intravenous; Male; Membrane Glycoproteins; Membrane Transport Proteins; Nerve Tissue Proteins; Papio; Piperazines; Self Administration; Tomography, Emission-Computed | 1999 |
Isoflurane anesthesia enhances the inhibitory effects of cocaine and GBR12909 on dopamine transporter: PET studies in combination with microdialysis in the monkey brain.
Topics: Anesthesia, Inhalation; Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Isoflurane; Kinetics; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Nerve Tissue Proteins; Piperazines; Receptors, Dopamine D2; Time Factors; Tomography, Emission-Computed; Wakefulness | 1999 |
Effect of cocaine, nomifensine, GBR 12909 and WIN 35428 on carbon fiber microelectrode sensitivity for voltammetric recording of dopamine.
Topics: Animals; Artifacts; Calibration; Carbon; Coated Materials, Biocompatible; Cocaine; Dopamine; Dopamine Uptake Inhibitors; Electrochemistry; Electrodes, Implanted; Equipment Failure; Fluorocarbon Polymers; Male; Microelectrodes; Nomifensine; Nucleus Accumbens; Piperazines; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity | 2000 |
Cholinergic neuronal modulation alters dopamine D2 receptor availability in vivo by regulating receptor affinity induced by facilitated synaptic dopamine turnover: positron emission tomography studies with microdialysis in the conscious monkey brain.
Topics: Animals; Brain; Carbon Radioisotopes; Carrier Proteins; Cholinergic Fibers; Cocaine; Dihydroxyphenylalanine; Dopamine; Dopamine Antagonists; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Macaca mulatta; Male; Membrane Glycoproteins; Membrane Transport Proteins; Microdialysis; Muscarinic Antagonists; Nerve Tissue Proteins; Neurons; Piperazines; Raclopride; Receptors, Dopamine D2; Scopolamine; Synapses; Tomography, Emission-Computed; Wakefulness | 2000 |
Synthesis and preliminary characterization of a high-affinity novel radioligand for the dopamine transporter.
Topics: Animals; Benzhydryl Compounds; Binding, Competitive; Carrier Proteins; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Ligands; Macaca mulatta; Male; Mazindol; Membrane Glycoproteins; Membrane Transport Proteins; Neostriatum; Nerve Tissue Proteins; Piperazines; Piperidines; Radioligand Assay; Tritium | 2001 |
[3-cis-3,5-Dimethyl-(1-piperazinyl)alkyl]-bis-(4'-fluorophenyl)amine analogues as novel probes for the dopamine transporter.
Topics: Animals; Carbazoles; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Membrane Glycoproteins; Membrane Transport Proteins; Molecular Probes; Nerve Tissue Proteins; Piperazines; Rats | 2001 |
Effects of GBR 12909, WIN 35,428 and indatraline on cocaine self-administration and cocaine seeking in rats.
Topics: Animals; Behavior, Addictive; Cocaine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Indans; Male; Methylamines; Neurotransmitter Uptake Inhibitors; Piperazines; Rats; Rats, Sprague-Dawley; Self Administration | 2002 |
Age-related changes in the striatal dopaminergic system in the living brain: a multiparametric PET study in conscious monkeys.
Topics: Aging; Animals; Benzazepines; Cocaine; Corpus Striatum; Dopamine; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Extracellular Space; Levodopa; Macaca mulatta; Magnetic Resonance Imaging; Male; Microdialysis; Piperazines; Raclopride; Tomography, Emission-Computed | 2002 |
Mutation of Trp84 and Asp313 of the dopamine transporter reveals similar mode of binding interaction for GBR12909 and benztropine as opposed to cocaine.
Topics: Amino Acid Substitution; Benztropine; Binding, Competitive; Cell Line; Cocaine; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Humans; Kidney; Ligands; Membrane Glycoproteins; Membrane Transport Proteins; Muscarinic Antagonists; Mutagenesis, Site-Directed; Nerve Tissue Proteins; Piperazines; Protein Binding; Sodium; Structure-Activity Relationship; Zinc | 2004 |
Interaction between a hydroxypiperidine analogue of 4-(2-benzhydryloxy-ethyl)-1-(4-fluorobenzyl)piperidine and Aspartate 68 in the human dopamine transporter.
Topics: Animals; Aspartic Acid; Benzhydryl Compounds; Binding Sites; Binding, Competitive; Biological Transport; Cell Line; Cell Membrane; Cerebral Cortex; Cocaine; Corpus Striatum; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dose-Response Relationship, Drug; Humans; Male; Membrane Glycoproteins; Membrane Transport Proteins; Models, Molecular; Mutation; Nerve Tissue Proteins; Norepinephrine; Piperazines; Piperidines; Protein Binding; Rats; Rats, Sprague-Dawley; Serotonin; Stereoisomerism; Synaptosomes; Tritium | 2004 |
Ex vivo evaluation of N-(3-[18F]fluoropropyl)-2 beta-carbomethoxy-3 beta-(4-fluorophenyl)nortropane in rats.
Topics: Animals; Binding, Competitive; Bone and Bones; Cerebellum; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Fluorine Radioisotopes; Limbic System; Male; Nortropanes; Piperazines; Radioligand Assay; Radionuclide Imaging; Radiopharmaceuticals; Rats; Rats, Sprague-Dawley; Tissue Distribution | 2008 |
Different effects of selective dopamine uptake inhibitors, GBR 12909 and WIN 35428, on HIV-1 Tat toxicity in rat fetal midbrain neurons.
Topics: Animals; Cell Survival; Cells, Cultured; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Embryo, Mammalian; HIV Envelope Protein gp120; Mesencephalon; Neurons; Piperazines; Protein Binding; Rats; Serotonin Plasma Membrane Transport Proteins; tat Gene Products, Human Immunodeficiency Virus | 2008 |
Interaction of cocaine-, benztropine-, and GBR12909-like compounds with wild-type and mutant human dopamine transporters: molecular features that differentially determine antagonist-binding properties.
Topics: Animals; Asparagine; Aspartic Acid; Benztropine; Binding, Competitive; Cell Line, Transformed; Cocaine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Drug Interactions; Humans; Leucine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Structure, Tertiary; Sodium; Structure-Activity Relationship; Transfection; Tritium; Tryptophan | 2008 |
Dopamine transporter-dependent and -independent striatal binding of the benztropine analog JHW 007, a cocaine antagonist with low abuse liability.
Topics: Adrenergic Uptake Inhibitors; Animals; Benztropine; Binding, Competitive; Cell Line, Tumor; Cell Membrane; Cocaine; Corpus Striatum; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Female; Histamine H1 Antagonists; Humans; Kinetics; Male; Mice; Mice, 129 Strain; Mice, Inbred Strains; Mice, Knockout; Neuroblastoma; Piperazines; Pirenzepine; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Muscarinic M1; Selective Serotonin Reuptake Inhibitors; Sodium; Triprolidine | 2010 |
Mutations at tyrosine 88, lysine 92 and tyrosine 470 of human dopamine transporter result in an attenuation of HIV-1 Tat-induced inhibition of dopamine transport.
Topics: Animals; Binding Sites; CHO Cells; Cocaine; Cricetinae; Cricetulus; Dopamine; Dopamine Plasma Membrane Transport Proteins; Humans; Lysine; Models, Molecular; Mutation; Piperazines; Protein Binding; Protein Conformation; tat Gene Products, Human Immunodeficiency Virus; Tyrosine | 2015 |