(22r)-22-hydroxycholesterol has been researched along with 3-chloro-4-(3-(7-propyl-3-trifluoromethyl-6-benzisoxazolyl)propylthio)phenylacetic acid in 2 studies
| Studies ((22r)-22-hydroxycholesterol) | Trials ((22r)-22-hydroxycholesterol) | Recent Studies (post-2010) ((22r)-22-hydroxycholesterol) | Studies (3-chloro-4-(3-(7-propyl-3-trifluoromethyl-6-benzisoxazolyl)propylthio)phenylacetic acid) | Trials (3-chloro-4-(3-(7-propyl-3-trifluoromethyl-6-benzisoxazolyl)propylthio)phenylacetic acid) | Recent Studies (post-2010) (3-chloro-4-(3-(7-propyl-3-trifluoromethyl-6-benzisoxazolyl)propylthio)phenylacetic acid) |
|---|---|---|---|---|---|
| 15 | 0 | 8 | 10 | 0 | 4 |
| Protein | Taxonomy | (22r)-22-hydroxycholesterol (IC50) | 3-chloro-4-(3-(7-propyl-3-trifluoromethyl-6-benzisoxazolyl)propylthio)phenylacetic acid (IC50) |
|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | Rattus norvegicus (Norway rat) | 0.0354 | |
| Peroxisome proliferator-activated receptor gamma | Homo sapiens (human) | 0.173 | |
| Oxysterols receptor LXR-beta | Homo sapiens (human) | 0.0265 | |
| Peroxisome proliferator-activated receptor delta | Homo sapiens (human) | 0.0055 | |
| Peroxisome proliferator-activated receptor alpha | Homo sapiens (human) | 0.2875 | |
| Oxysterols receptor LXR-alpha | Homo sapiens (human) | 0.0337 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baffic, J; Bouffard, A; Burton, C; Chao, YS; Chen, S; Chen, TS; Dropinski, J; Hayes, N; Hernandez, M; Jones, AB; Lam, MH; Li, X; Liu, W; Macnaul, K; McCormick, S; Menke, JG; Ondeyka, JG; Sharma, N; Singh, SB; Sparrow, CP; Wang, J | 1 |
| Ali, A; Beck, HT; Borris, RP; Chavez, F; de Jong, W; Guan, Z; Hayes, N; Herath, KB; Jayasuriya, H; MacNaul, K; Menke, JG; Moss, J; Ondeyka, JG; Schulman, M; Sharma, N; Singh, SB; Slattery, M; Stevenson, DW; Tiwari, S; Zamora, N | 1 |
2 other study(ies) available for (22r)-22-hydroxycholesterol and 3-chloro-4-(3-(7-propyl-3-trifluoromethyl-6-benzisoxazolyl)propylthio)phenylacetic acid
| Article | Year |
|---|---|
Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters.
Topics: Abietanes; Animals; Area Under Curve; Biotransformation; Cell Line; Cholesterol, HDL; Cricetinae; Dimerization; Humans; Male; Mice; Phenanthrenes; Rats; Rats, Sprague-Dawley; Receptors, Cytoplasmic and Nuclear; Structure-Activity Relationship | 2005 |
Diterpenoid, steroid, and triterpenoid agonists of liver X receptors from diversified terrestrial plants and marine sources.
Topics: Animals; Annonaceae; Anthozoa; Bahamas; Betulinic Acid; Cactaceae; Campanulaceae; Cells, Cultured; Costa Rica; Diterpenes; DNA-Binding Proteins; Guyana; Humans; Inhibitory Concentration 50; Liver X Receptors; Molecular Structure; Olacaceae; Orphan Nuclear Receptors; Pentacyclic Triterpenes; Peru; Pinaceae; Plants, Medicinal; Polycyclic Aromatic Hydrocarbons; Receptors, Cytoplasmic and Nuclear; Steroids; Triterpenes; United States | 2005 |