Page last updated: 2024-09-03

(20s)-20-hydroxycholesterol and gdc 0449

(20s)-20-hydroxycholesterol has been researched along with gdc 0449 in 2 studies

Compound Research Comparison

Studies
((20s)-20-hydroxycholesterol)
Trials
((20s)-20-hydroxycholesterol)
Recent Studies (post-2010)
((20s)-20-hydroxycholesterol)
Studies
(gdc 0449)
Trials
(gdc 0449)
Recent Studies (post-2010) (gdc 0449)
5101466668611

Protein Interaction Comparison

ProteinTaxonomy(20s)-20-hydroxycholesterol (IC50)gdc 0449 (IC50)
Sodium-dependent dopamine transporterRattus norvegicus (Norway rat)0.02
Sodium-dependent serotonin transporterRattus norvegicus (Norway rat)0.02
Smoothened homologMus musculus (house mouse)0.07
Sonic hedgehog proteinHomo sapiens (human)0.8825
Sonic hedgehog proteinMus musculus (house mouse)0.0077
Smoothened homologHomo sapiens (human)0.0222
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.4

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Giannis, A; Heretsch, P; Tzagkaroulaki, L1
Gu, T; Hu, T; Jiang, Z; Li, R; Liu, X; Lu, W; Qiu, Y; Tao, H; Wu, Y; Xu, F; Xu, Y; Xue, D; Zhao, F; Zhao, S; Zhong, G; Zhou, F1

Reviews

1 review(s) available for (20s)-20-hydroxycholesterol and gdc 0449

ArticleYear
Modulators of the hedgehog signaling pathway.
    Bioorganic & medicinal chemistry, 2010, Sep-15, Volume: 18, Issue:18

    Topics: Antineoplastic Agents; Hedgehog Proteins; Humans; Neoplasms; Signal Transduction; Veratrum Alkaloids

2010

Other Studies

1 other study(ies) available for (20s)-20-hydroxycholesterol and gdc 0449

ArticleYear
Elucidation of Distinct Modular Assemblies of Smoothened Receptor by Bitopic Ligand Measurement.
    Journal of medicinal chemistry, 2021, 09-23, Volume: 64, Issue:18

    Topics: Anilides; Animals; Binding Sites; HEK293 Cells; Humans; Hydroxycholesterols; Ligands; Mice; NIH 3T3 Cells; Polyethylene Glycols; Protein Domains; Pyridines; Smoothened Receptor

2021