(20s)-20-hydroxycholesterol has been researched along with cyclopamine in 5 studies
| Studies ((20s)-20-hydroxycholesterol) | Trials ((20s)-20-hydroxycholesterol) | Recent Studies (post-2010) ((20s)-20-hydroxycholesterol) | Studies (cyclopamine) | Trials (cyclopamine) | Recent Studies (post-2010) (cyclopamine) |
|---|---|---|---|---|---|
| 51 | 0 | 14 | 658 | 0 | 343 |
| Protein | Taxonomy | (20s)-20-hydroxycholesterol (IC50) | cyclopamine (IC50) |
|---|---|---|---|
| Integrin beta-1 | Homo sapiens (human) | 1.312 | |
| Integrin alpha-4 | Homo sapiens (human) | 1.312 | |
| Smoothened homolog | Mus musculus (house mouse) | 1.271 | |
| Sonic hedgehog protein | Homo sapiens (human) | 0.6 | |
| Sonic hedgehog protein | Mus musculus (house mouse) | 0.7373 | |
| Smoothened homolog | Homo sapiens (human) | 0.2147 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giannis, A; Heretsch, P; Tzagkaroulaki, L | 1 |
| Gu, T; Hu, T; Jiang, Z; Li, R; Liu, X; Lu, W; Qiu, Y; Tao, H; Wu, Y; Xu, F; Xu, Y; Xue, D; Zhao, F; Zhao, S; Zhong, G; Zhou, F | 1 |
| Amantea, CM; Hahn, TJ; Kim, WK; Meliton, V; Parhami, F | 1 |
| Carlson, M; Hahn, TJ; Kim, WK; Meliton, V; Nelson, SF; Parhami, F; Tetradis, S; Weinmaster, G | 1 |
| Berretta, A; Clarkson, AN; Gowing, EK; Jasoni, CL | 1 |
1 review(s) available for (20s)-20-hydroxycholesterol and cyclopamine
| Article | Year |
|---|---|
Modulators of the hedgehog signaling pathway.
Topics: Antineoplastic Agents; Hedgehog Proteins; Humans; Neoplasms; Signal Transduction; Veratrum Alkaloids | 2010 |
4 other study(ies) available for (20s)-20-hydroxycholesterol and cyclopamine
| Article | Year |
|---|---|
Elucidation of Distinct Modular Assemblies of Smoothened Receptor by Bitopic Ligand Measurement.
Topics: Anilides; Animals; Binding Sites; HEK293 Cells; Humans; Hydroxycholesterols; Ligands; Mice; NIH 3T3 Cells; Polyethylene Glycols; Protein Domains; Pyridines; Smoothened Receptor | 2021 |
20(S)-hydroxycholesterol inhibits PPARgamma expression and adipogenic differentiation of bone marrow stromal cells through a hedgehog-dependent mechanism.
Topics: Adipogenesis; Animals; Bone Marrow Cells; CCAAT-Enhancer-Binding Protein-alpha; Cell Line; Hedgehog Proteins; Hydroxycholesterols; Mice; PPAR gamma; Retinoid X Receptors; Stromal Cells; Veratrum Alkaloids | 2007 |
Osteogenic oxysterol, 20(S)-hydroxycholesterol, induces notch target gene expression in bone marrow stromal cells.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Bone Marrow Cells; Cell Culture Techniques; Cell Cycle Proteins; Fibroblasts; Gene Expression; Hedgehog Proteins; Homeodomain Proteins; Hydroxycholesterols; Liver X Receptors; Mice; Orphan Nuclear Receptors; Osteogenesis; Receptors, Notch; RNA, Messenger; Stromal Cells; Transcription Factor HES-1; Veratrum Alkaloids | 2010 |
Sonic hedgehog stimulates neurite outgrowth in a mechanical stretch model of reactive-astrogliosis.
Topics: Animals; Animals, Newborn; Astrocytes; Cerebral Cortex; Coculture Techniques; Gene Expression Regulation; Gliosis; Hedgehog Proteins; Hydroxycholesterols; Mice; Mice, Inbred C57BL; Models, Biological; Neuronal Outgrowth; Neurons; Pressure; Primary Cell Culture; Pyrimidines; Signal Transduction; Smoothened Receptor; src-Family Kinases; Stress, Mechanical; Veratrum Alkaloids; Zinc Finger Protein GLI1 | 2016 |