(20s)-20-hydroxycholesterol has been researched along with abt-199 in 1 studies
| Studies ((20s)-20-hydroxycholesterol) | Trials ((20s)-20-hydroxycholesterol) | Recent Studies (post-2010) ((20s)-20-hydroxycholesterol) | Studies (abt-199) | Trials (abt-199) | Recent Studies (post-2010) (abt-199) |
|---|---|---|---|---|---|
| 51 | 0 | 14 | 1,483 | 150 | 1,469 |
| Protein | Taxonomy | (20s)-20-hydroxycholesterol (IC50) | abt-199 (IC50) |
|---|---|---|---|
| Apoptosis regulator Bcl-2 | Homo sapiens (human) | 0.0392 | |
| Bcl-2-like protein 1 | Homo sapiens (human) | 0.0667 | |
| Induced myeloid leukemia cell differentiation protein Mcl-1 | Homo sapiens (human) | 0.0044 | |
| Aspartyl/asparaginyl beta-hydroxylase | Homo sapiens (human) | 1.445 | |
| Bcl-2-related protein A1 | Homo sapiens (human) | 0.0044 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, TM; Huang, WJ; Tan, WF; Tang, WG; Wang, J; Yang, J; Zhang, Y | 1 |
1 other study(ies) available for (20s)-20-hydroxycholesterol and abt-199
| Article | Year |
|---|---|
ABT-199 inhibits Hedgehog pathway by acting as a competitive inhibitor of oxysterol, rather as a BH3 mimetic.
Topics: Animals; Antineoplastic Agents; Binding Sites; Bridged Bicyclo Compounds, Heterocyclic; Cell Line, Tumor; Drug Resistance, Neoplasm; Hedgehog Proteins; Humans; Hydroxycholesterols; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplasms; NIH 3T3 Cells; Protein Binding; Signal Transduction; Smoothened Receptor; Sulfonamides | 2021 |