(20s)-20-hydroxycholesterol has been researched along with 25-hydroxycholesterol in 13 studies
| Studies ((20s)-20-hydroxycholesterol) | Trials ((20s)-20-hydroxycholesterol) | Recent Studies (post-2010) ((20s)-20-hydroxycholesterol) | Studies (25-hydroxycholesterol) | Trials (25-hydroxycholesterol) | Recent Studies (post-2010) (25-hydroxycholesterol) |
|---|---|---|---|---|---|
| 51 | 0 | 14 | 853 | 3 | 243 |
| Protein | Taxonomy | (20s)-20-hydroxycholesterol (IC50) | 25-hydroxycholesterol (IC50) |
|---|---|---|---|
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.3 | |
| Sterol regulatory element-binding protein 2 | Homo sapiens (human) | 0.3 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (30.77) | 18.7374 |
| 1990's | 3 (23.08) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 4 (30.77) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bledsoe, RK; Collins, JL; Consler, TG; Galardi, CM; Lambert, MH; Li, D; McKee, DD; Moore, JT; Moore, LB; Parks, DJ; Russel, JS; Spencer, TA; Watson, MA; Willson, TM | 1 |
| Giannis, A; Heretsch, P; Tzagkaroulaki, L | 1 |
| Dodo, K; Hashimoto, Y; Karaki, F; Ohgane, K | 1 |
| Corman, A; DeBerardinis, AM; Hadden, MK | 1 |
| Dodo, K; Hashimoto, Y; Karaki, F; Noguchi-Yachide, T; Ohgane, K | 1 |
| Tuckey, RC | 1 |
| Seillan, C | 1 |
| Hoyer, PB; Niswender, GD | 1 |
| Daynes, RA; Sherris, D; Spangrude, GJ | 1 |
| Alsema, GJ; Degenhart, HJ; Hoogerbrugge, J | 1 |
| Buckingham, L; Duncan, JL | 1 |
| Duedahl, C; Nielsen, JH; Olsen, CE; Skibsted, LH | 1 |
| Redman, CM; Xia, H | 1 |
1 review(s) available for (20s)-20-hydroxycholesterol and 25-hydroxycholesterol
| Article | Year |
|---|---|
Modulators of the hedgehog signaling pathway.
Topics: Antineoplastic Agents; Hedgehog Proteins; Humans; Neoplasms; Signal Transduction; Veratrum Alkaloids | 2010 |
12 other study(ies) available for (20s)-20-hydroxycholesterol and 25-hydroxycholesterol
| Article | Year |
|---|---|
Pharmacophore analysis of the nuclear oxysterol receptor LXRalpha.
Topics: Amino Acid Sequence; Animals; Binding Sites; Blotting, Western; Cell Line; Cell Nucleus; Cell-Free System; Chlorocebus aethiops; Cholesterol; Cholic Acids; DNA-Binding Proteins; Energy Transfer; Fluorescence; Histone Acetyltransferases; Hydroxycholesterols; Ketocholesterols; Liver X Receptors; Models, Molecular; Molecular Sequence Data; Nuclear Receptor Coactivator 1; Orphan Nuclear Receptors; Receptors, Cytoplasmic and Nuclear; Receptors, Steroid; Stereoisomerism; Sterols; Structure-Activity Relationship; Transcription Factors; Tryptophan | 2001 |
Structure-activity relationship studies of Niemann-Pick type C1-like 1 (NPC1L1) ligands identified by screening assay monitoring pharmacological chaperone effect.
Topics: Anticholesteremic Agents; Azetidines; Binding Sites; Biological Transport; Carbamates; Ezetimibe; HEK293 Cells; Humans; Ligands; Membrane Proteins; Membrane Transport Proteins; Mutation; Steroids; Structure-Activity Relationship | 2013 |
Structure-activity relationships for side chain oxysterol agonists of the hedgehog signaling pathway.
Topics: | 2012 |
Structure-activity relationships of oxysterol-derived pharmacological chaperones for Niemann-Pick type C1 protein.
Topics: Carrier Proteins; Dose-Response Relationship, Drug; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Molecular Structure; Mutation; Niemann-Pick C1 Protein; Niemann-Pick Disease, Type C; Sterols; Structure-Activity Relationship | 2014 |
Cholesterol side-chain cleavage by mitochondria from the human placenta. Studies using hydroxycholesterols as substrates.
Topics: Animals; Cattle; Cholesterol Side-Chain Cleavage Enzyme; Female; Humans; Hydroxycholesterols; Hydroxylation; Mitochondria; Placenta; Pregnenolone; Rats | 1992 |
Oxysterol mediated changes in fatty acid distribution and lipid synthesis in cultured bovine aortic smooth muscle cells.
Topics: Acetates; Acetic Acid; Animals; Aorta; Arachidonic Acid; Arachidonic Acids; Cattle; Cells, Cultured; Cholestanols; Fatty Acids; Hydroxycholesterols; Lipids; Muscle, Smooth, Vascular; Oleic Acid; Oleic Acids; Phospholipids; Triglycerides | 1990 |
The regulation of steroidogenesis is different in the two types of ovine luteal cells.
Topics: Animals; Azides; Blood; Cholera Toxin; Cholesterol; Colforsin; Corpus Luteum; Cyclic AMP; Diterpenes; Female; Hydroxycholesterols; Luteinizing Hormone; Male; Progesterone; Sheep | 1985 |
Inhibitory effects of various oxygenated sterols on the differentiation and function of tumor-specific cytotoxic T lymphocytes.
Topics: Animals; Cell Differentiation; Cholesterol; Cytotoxicity, Immunologic; Dimyristoylphosphatidylcholine; Female; Fibrosarcoma; Hydroxycholesterols; Liposomes; Lymph Nodes; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Phosphatidylcholines; Sterols; T-Lymphocytes | 1982 |
Side chain cleavage of hydroxylated sterols by bovine adrenal cortex mitochondria: observation of 25-hydroxylase activity during incubation at pH 7.80.
Topics: Adrenal Cortex; Animals; Cattle; Cholestanetriol 26-Monooxygenase; Hydrogen-Ion Concentration; Hydroxycholesterols; Hydroxylation; Mitochondria; Pregnenolone; Steroid Hydroxylases | 1980 |
Resistance to streptolysin O in mammalian cells treated with oxygenated derivatives of cholesterol. Cholesterol content of resistant cells and recovery of streptolysin O sensitivity.
Topics: Bacterial Proteins; Blood Physiological Phenomena; Cholesterol; Drug Resistance; HeLa Cells; Humans; Hydroxycholesterols; L Cells; Mevalonic Acid; Streptolysins | 1980 |
Isolation and quantification of cholesterol oxides in dairy products by selected ion monitoring mass spectrometry.
Topics: Cholestanols; Cholesterol; Cholesterol Esters; Chromatography, High Pressure Liquid; Dairy Products; Gas Chromatography-Mass Spectrometry; Hydroxycholesterols; Ketocholesterols; Mass Spectrometry; Oxidation-Reduction; Oxides; Triglycerides | 1995 |
Oxysterols suppress constitutive fibrinogen expression.
Topics: Acute-Phase Reaction; alpha 1-Antitrypsin; Animals; Carcinoma, Hepatocellular; CCAAT-Enhancer-Binding Proteins; Cholesterol; DNA-Binding Proteins; Feedback, Physiological; Fibrinogen; Gene Expression Regulation; Hepatocytes; Humans; Hydroxycholesterols; Interleukin-6; Liver Neoplasms; Liver Neoplasms, Experimental; Liver X Receptors; Orphan Nuclear Receptors; Rats; Receptors, Cytoplasmic and Nuclear; Recombinant Fusion Proteins; RNA, Messenger; Sterol Regulatory Element Binding Protein 1; Sterol Regulatory Element Binding Protein 2; Sulfonamides; Transcription Factors; Transfection; Tumor Cells, Cultured | 2003 |