(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine and vofopitant

(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine has been researched along with vofopitant in 2 studies

Compound Research Comparison

Studies ((2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine)	Trials ((2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine)	Recent Studies (post-2010) ((2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine)	Studies (vofopitant)	Trials (vofopitant)	Recent Studies (post-2010) (vofopitant)
9	0	1	71	8	12

Protein Interaction Comparison

Protein	Taxonomy	(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine (IC50)	vofopitant (IC50)
Substance-P receptor	Homo sapiens (human)		0.0001

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (50.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Armour, DR; Beattie, DT; Gale, JD; Gardner, CJ; Hawcock, AB; Kilpatrick, GJ; Twissell, DJ; Ward, P	1
Bergström, M; Cable, KM; Fasth, KJ; Kilpatrick, G; Långström, B; Sutherland, DR; Ward, P; Wipperman, MD	1

Other Studies

2 other study(ies) available for (2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine and vofopitant

Article	Year
GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity. Regulatory peptides, 1996, Aug-27, Volume: 65, Issue:1 Topics: Administration, Oral; Animals; Antiemetics; Cisplatin; Dogs; Dose-Response Relationship, Drug; Ferrets; Humans; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Shrews; Stereoisomerism; Tetrazoles	1996
Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171--PET studies in rhesus monkey. Neuropharmacology, 2000, Feb-14, Volume: 39, Issue:4 Topics: Animals; Brain; Carbon Radioisotopes; Ligands; Macaca mulatta; Neurokinin-1 Receptor Antagonists; Piperidines; Protein Binding; Receptors, Neurokinin-1; Tetrazoles; Tomography, Emission-Computed	2000

Article

Year

GR205171: a novel antagonist with high affinity for the tachykinin NK1 receptor, and potent broad-spectrum anti-emetic activity.

Regulatory peptides, 1996, Aug-27, Volume: 65, Issue:1

Topics: Administration, Oral; Animals; Antiemetics; Cisplatin; Dogs; Dose-Response Relationship, Drug; Ferrets; Humans; Male; Motor Activity; Neurokinin-1 Receptor Antagonists; Piperidines; Receptors, Neurokinin-1; Shrews; Stereoisomerism; Tetrazoles

1996

Brain uptake and receptor binding of two [11C]labelled selective high affinity NK1-antagonists, GR203040 and GR205171--PET studies in rhesus monkey.

Neuropharmacology, 2000, Feb-14, Volume: 39, Issue:4

Topics: Animals; Brain; Carbon Radioisotopes; Ligands; Macaca mulatta; Neurokinin-1 Receptor Antagonists; Piperidines; Protein Binding; Receptors, Neurokinin-1; Tetrazoles; Tomography, Emission-Computed

2000