(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine and cp 96345

(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine has been researched along with cp 96345 in 2 studies

Compound Research Comparison

Studies ((2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine)	Trials ((2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine)	Recent Studies (post-2010) ((2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine)	Studies (cp 96345)	Trials (cp 96345)	Recent Studies (post-2010) (cp 96345)
9	0	1	403	1	16

Protein Interaction Comparison

Protein	Taxonomy	(2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine (IC50)	cp 96345 (IC50)
Substance-P receptor	Homo sapiens (human)		0.0028
Substance-P receptor	Cavia porcellus (domestic guinea pig)		0.0004

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Alvaro, G; Braggio, S; Carletti, R; Corsi, M; Di Fabio, R; Gerrard, PA; Griffante, C; Marchioro, C; Melotto, S; Piccoli, L; Poffe, A; Pozzan, A; Ratti, E; Spada, S; Tranquillini, E; Trower, M	1
Gallantine, EL; Meert, TF	1

Other Studies

2 other study(ies) available for (2-methoxy-5-tetrazol-1-ylbenzyl)(2-phenylpiperidin-3-yl)amine and cp 96345

Article	Year
Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate. Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21 Topics: Animals; Antidepressive Agents; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; CHO Cells; Cricetinae; Cricetulus; Dogs; Female; Gerbillinae; Half-Life; Humans; Male; Models, Molecular; Molecular Conformation; Neurokinin-1 Receptor Antagonists; Piperazines; Piperidines; Protein Binding; Rats; Receptors, Neurokinin-1	2013
Attenuation of the gerbil writhing response by mu-, kappa- and delta-opioids, and NK-1, -2 and -3 receptor antagonists. Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:1 Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdomen; Acetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Biphenyl Compounds; Butanols; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Fentanyl; Gerbillinae; Malates; Morphine; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Pain Measurement; Piperidines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrazoles	2004

Article

Year

Identification, biological characterization and pharmacophoric analysis of a new potent and selective NK1 receptor antagonist clinical candidate.

Bioorganic & medicinal chemistry, 2013, Nov-01, Volume: 21, Issue:21

Topics: Animals; Antidepressive Agents; Behavior, Animal; Bridged Bicyclo Compounds, Heterocyclic; CHO Cells; Cricetinae; Cricetulus; Dogs; Female; Gerbillinae; Half-Life; Humans; Male; Models, Molecular; Molecular Conformation; Neurokinin-1 Receptor Antagonists; Piperazines; Piperidines; Protein Binding; Rats; Receptors, Neurokinin-1

2013

Attenuation of the gerbil writhing response by mu-, kappa- and delta-opioids, and NK-1, -2 and -3 receptor antagonists.

Pharmacology, biochemistry, and behavior, 2004, Volume: 79, Issue:1

Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Abdomen; Acetic Acid; Analgesics, Opioid; Animals; Behavior, Animal; Biphenyl Compounds; Butanols; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Fentanyl; Gerbillinae; Malates; Morphine; Muscle Contraction; Neurokinin-1 Receptor Antagonists; Pain Measurement; Piperidines; Receptors, Neurokinin-2; Receptors, Neurokinin-3; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Tetrazoles

2004