Compounds > (2-(trimethylammonium)ethyl)methanethiosulfonate
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(2-(trimethylammonium)ethyl)methanethiosulfonate and verapamil

(2-(trimethylammonium)ethyl)methanethiosulfonate has been researched along with verapamil in 2 studies

Compound Research Comparison

Studies
((2-(trimethylammonium)ethyl)methanethiosulfonate)		Trials
((2-(trimethylammonium)ethyl)methanethiosulfonate)		Recent Studies (post-2010)
((2-(trimethylammonium)ethyl)methanethiosulfonate)		Studies
(verapamil)		Trials
(verapamil)		Recent Studies (post-2010) (verapamil)
14301717,6211,5272,067

Protein Interaction Comparison

ProteinTaxonomy(2-(trimethylammonium)ethyl)methanethiosulfonate (IC50)verapamil (IC50)
Solute carrier family 22 member 1 Homo sapiens (human)6.8
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.297
ATP-dependent translocase ABCB1Mus musculus (house mouse)2
ATP-dependent translocase ABCB1Homo sapiens (human)2.2346
Cytochrome P450 3A4Homo sapiens (human)3.8008
Alpha-2A adrenergic receptorHomo sapiens (human)0.579
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)3.02
ATP-dependent translocase ABCB1Mus musculus (house mouse)10
Catechol O-methyltransferaseHomo sapiens (human)0.2
Potassium voltage-gated channel subfamily A member 3Homo sapiens (human)8
Histamine H2 receptorHomo sapiens (human)2.59
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.442
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.297
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)3.02
Sodium-dependent serotonin transporterHomo sapiens (human)0.24
Multidrug resistance-associated protein 1 Homo sapiens (human)5.598
D(3) dopamine receptorHomo sapiens (human)0.186
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.165
5-hydroxytryptamine receptor 7Cavia porcellus (domestic guinea pig)6.8
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.2
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3945
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.2
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.175
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.1934

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bartlett, MC; Clarke, DM; Loo, TW1
Grissmer, S; Schmid, SI1

Other Studies

2 other study(ies) available for (2-(trimethylammonium)ethyl)methanethiosulfonate and verapamil

ArticleYear
The drug-binding pocket of the human multidrug resistance P-glycoprotein is accessible to the aqueous medium.
    Biochemistry, 2004, Sep-28, Volume: 43, Issue:38

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; ATP Binding Cassette Transporter, Subfamily B, Member 1; Binding Sites; Biological Transport; Buffers; Cell Line; Colchicine; Cyclosporine; Cysteine; Drug Resistance, Multiple; Gene Expression Regulation; Humans; Hydrolysis; Isoleucine; Mesylates; Mutation; Rhodamines; Verapamil; Water

2004
Effect of verapamil on the action of methanethiosulfonate reagents on human voltage-gated K(v)1.3 channels: implications for the C-type inactivated state.
    British journal of pharmacology, 2011, Volume: 163, Issue:3

    Topics: Animals; Chlorocebus aethiops; COS Cells; Ethyl Methanesulfonate; Humans; Ion Channel Gating; Kv1.3 Potassium Channel; Mesylates; Mutation; Patch-Clamp Techniques; Verapamil

2011